PPData.csv

1,M,L,p.M1L,Missense,-2.51652937334305,LOF
1,M,V,p.M1V,Missense,-2.02564472903696,LOF
1,M,L,p.M1L,Missense,-1.9656286042014,LOF
1,M,K,p.M1K,Missense,-1.6367004566288,LOF
1,M,T,p.M1T,Missense,-1.65656907663554,LOF
1,M,R,p.M1R,Missense,-2.4815795549735,LOF
1,M,I,p.M1I,Missense,-2.50212823274764,LOF
1,M,I,p.M1I,Missense,-2.22610742672219,LOF
1,M,I,p.M1I,Missense,-1.89730149043368,LOF
2,D,N,p.D2N,Missense,-0.682954463032835,FUNC
2,D,H,p.D2H,Missense,-1.47383080582929,LOF
2,D,Y,p.D2Y,Missense,-0.256094696263827,FUNC
2,D,A,p.D2A,Missense,-0.180781768085747,FUNC
2,D,G,p.D2G,Missense,-1.01782797782734,INT
2,D,V,p.D2V,Missense,-1.1594980212777,INT
2,D,E,p.D2E,Missense,-0.00212655811895148,FUNC
2,D,D,p.D2=,Synonymous,-0.0983187489626474,FUNC
2,D,E,p.D2E,Missense,0.08869598453292141,FUNC
3,L,I,p.L3I,Missense,0.0219005007232084,FUNC
3,L,L,p.L3=,Synonymous,-0.0179998194743001,FUNC
3,L,V,p.L3V,Missense,-0.0500459285012336,FUNC
3,L,*,p.L3*,Nonsense,-2.67410841645749,LOF
3,L,S,p.L3S,Missense,-0.0664564027844771,FUNC
3,L,*,p.L3*,Nonsense,-3.65034797244986,LOF
3,L,F,p.L3F,Missense,-0.341922832016336,FUNC
3,L,L,p.L3=,Synonymous,0.21176742138953,FUNC
3,L,F,p.L3F,Missense,-0.605356370320219,FUNC
4,S,T,p.S4T,Missense,0.0376395031614976,FUNC
4,S,P,p.S4P,Missense,-0.330095865138841,FUNC
4,S,A,p.S4A,Missense,0.0736912909433332,FUNC
4,S,Y,p.S4Y,Missense,-0.255390243949249,FUNC
4,S,C,p.S4C,Missense,-0.245299044058534,FUNC
4,S,F,p.S4F,Missense,-0.495238709687705,FUNC
4,S,S,p.S4=,Synonymous,-0.388970197742591,FUNC
4,S,S,p.S4=,Synonymous,0.238336299346863,FUNC
4,S,S,p.S4=,Synonymous,-0.142624097579656,FUNC
5,A,T,p.A5T,Missense,-0.0878381970969909,FUNC
5,A,P,p.A5P,Missense,-0.892859052937805,INT
5,A,S,p.A5S,Missense,-0.261440553945555,FUNC
5,A,D,p.A5D,Missense,0.132687421458342,FUNC
5,A,G,p.A5G,Missense,-0.5916092753888,FUNC
5,A,V,p.A5V,Missense,0.314079800080404,FUNC
5,A,A,p.A5=,Synonymous,0.154157649377929,FUNC
5,A,A,p.A5=,Synonymous,-0.422681586594637,FUNC
5,A,A,p.A5=,Synonymous,-0.166669459142941,FUNC
6,L,I,p.L6I,Missense,-0.114585698691009,FUNC
6,L,V,p.L6V,Missense,0.163586304203768,FUNC
6,L,F,p.L6F,Missense,-0.180958272634677,FUNC
6,L,H,p.L6H,Missense,-0.0381968456076487,FUNC
6,L,P,p.L6P,Missense,0.326952510113036,FUNC
6,L,R,p.L6R,Missense,-0.195369135488555,FUNC
6,L,L,p.L6=,Synonymous,-0.0393050103460963,FUNC
6,L,L,p.L6=,Synonymous,-0.00548045140131322,FUNC
6,L,L,p.L6=,Synonymous,-0.0318629778553975,FUNC
7,R,S,p.R7S,Missense,-0.921591673894526,INT
7,R,G,p.R7G,Missense,-0.311500807458905,FUNC
7,R,C,p.R7C,Missense,-0.148867100203426,FUNC
7,R,H,p.R7H,Missense,-0.539420688452674,FUNC
7,R,P,p.R7P,Missense,-0.192425586356532,FUNC
7,R,L,p.R7L,Missense,-0.0164585518325097,FUNC
7,R,R,p.R7=,Synonymous,-0.256547625476716,FUNC
7,R,R,p.R7=,Synonymous,-0.196967451557336,FUNC
7,R,R,p.R7=,Synonymous,0.275561384077285,FUNC
8,V,I,p.V8I,Missense,-0.56091866284254,FUNC
8,V,L,p.V8L,Missense,-0.448267493087877,FUNC
8,V,F,p.V8F,Missense,-0.569226807221544,FUNC
8,V,D,p.V8D,Missense,-1.12167589876894,INT
8,V,A,p.V8A,Missense,0.22340649707733,FUNC
8,V,G,p.V8G,Missense,-0.312289330139422,FUNC
8,V,V,p.V8=,Synonymous,0.0142807347774057,FUNC
8,V,V,p.V8=,Synonymous,0.327422988892546,FUNC
8,V,V,p.V8=,Synonymous,-0.543137762402507,FUNC
9,E,K,p.E9K,Missense,-0.649333464018167,FUNC
9,E,Q,p.E9Q,Missense,-0.292376184810078,FUNC
9,E,*,p.E9*,Nonsense,-1.94255575488369,LOF
9,E,A,p.E9A,Missense,0.236742528994922,FUNC
9,E,G,p.E9G,Missense,-0.145407855200815,FUNC
9,E,V,p.E9V,Missense,-0.252637874039314,FUNC
9,E,D,p.E9D,Missense,-0.129703625139465,FUNC
9,E,E,p.E9=,Synonymous,-0.200679811161979,FUNC
9,E,D,p.E9D,Missense,-0.401406461500291,FUNC
10,E,K,p.E10K,Missense,-0.769615878983769,INT
10,E,Q,p.E10Q,Missense,-0.403286540026543,FUNC
10,E,*,p.E10*,Nonsense,-2.35272738562521,LOF
10,E,A,p.E10A,Missense,-0.0319006778297286,FUNC
10,E,G,p.E10G,Missense,-0.183632895124666,FUNC
10,E,V,p.E10V,Missense,-0.851903168569957,INT
10,E,D,p.E10D,Missense,-0.116327290438585,FUNC
10,E,E,p.E10=,Synonymous,-0.308519545564318,FUNC
10,E,D,p.E10D,Missense,0.0104485547113585,FUNC
11,V,I,p.V11I,Missense,-0.313424946240524,FUNC
11,V,L,p.V11L,Missense,-1.14195506703003,INT
11,V,L,p.V11L,Missense,-1.1680166594663,INT
11,V,E,p.V11E,Missense,-2.20488274643452,LOF
11,V,A,p.V11A,Missense,-0.126650277002018,FUNC
11,V,G,p.V11G,Missense,-2.47449709015521,LOF
11,V,V,p.V11=,Synonymous,0.0628013912002851,FUNC
11,V,V,p.V11=,Synonymous,0.168246095010134,FUNC
11,V,V,p.V11=,Synonymous,0.00898740476474751,FUNC
12,Q,K,p.Q12K,Missense,0.0785666221560315,FUNC
12,Q,E,p.Q12E,Missense,-0.387357108661802,FUNC
12,Q,*,p.Q12*,Nonsense,-1.89246157412393,LOF
12,Q,P,p.Q12P,Missense,-2.1847547529789,LOF
12,Q,R,p.Q12R,Missense,0.31364873883553,FUNC
12,Q,L,p.Q12L,Missense,0.119074367258883,FUNC
12,Q,H,p.Q12H,Missense,0.0311627938030909,FUNC
12,Q,Q,p.Q12=,Synonymous,-0.113496938607851,FUNC
12,Q,H,p.Q12H,Missense,-0.175873386814908,FUNC
13,N,H,p.N13H,Missense,0.155809001215628,FUNC
13,N,D,p.N13D,Missense,0.316276815670123,FUNC
13,N,Y,p.N13Y,Missense,-0.504029039954484,FUNC
13,N,T,p.N13T,Missense,0.171094586178767,FUNC
13,N,S,p.N13S,Missense,-0.0720163850844163,FUNC
13,N,I,p.N13I,Missense,-0.578107176714707,FUNC
13,N,K,p.N13K,Missense,-0.0418711301411099,FUNC
13,N,N,p.N13=,Synonymous,-0.108512374174145,FUNC
13,N,K,p.N13K,Missense,-0.299074923117612,FUNC
14,V,I,p.V14I,Missense,-0.00656432258964985,FUNC
14,V,L,p.V14L,Missense,-0.548239954638154,FUNC
14,V,F,p.V14F,Missense,-1.43176219554685,LOF
14,V,D,p.V14D,Missense,-1.23390488739974,INT
14,V,A,p.V14A,Missense,0.062406302949053,FUNC
14,V,G,p.V14G,Missense,-1.8612150523609,LOF
14,V,V,p.V14=,Synonymous,-0.321266376663658,FUNC
14,V,V,p.V14=,Synonymous,-0.231817926935682,FUNC
14,V,V,p.V14=,Synonymous,-0.191276668017017,FUNC
15,I,L,p.I15L,Missense,0.0826831586701175,FUNC
15,I,V,p.I15V,Missense,-0.58041586484571,FUNC
15,I,F,p.I15F,Missense,-1.32040948296724,INT
15,I,N,p.I15N,Missense,-2.63305342929592,LOF
15,I,T,p.I15T,Missense,-2.09697257117144,LOF
15,I,S,p.I15S,Missense,-1.83471135433156,LOF
15,I,I,p.I15=,Synonymous,0.348291059736837,FUNC
15,I,I,p.I15=,Synonymous,0.0211553121759141,FUNC
15,I,M,p.I15M,Missense,-0.638691852982005,FUNC
16,N,H,p.N16H,Missense,-0.140590292773857,FUNC
16,N,D,p.N16D,Missense,-0.172551302798021,FUNC
16,N,Y,p.N16Y,Missense,-0.353923267413801,FUNC
16,N,T,p.N16T,Missense,0.148421579767673,FUNC
16,N,S,p.N16S,Missense,-0.333605413119007,FUNC
16,N,I,p.N16I,Missense,0.510672527059461,FUNC
16,N,K,p.N16K,Missense,-0.291203178754204,FUNC
16,N,N,p.N16=,Synonymous,0.0634310486770521,FUNC
16,N,K,p.N16K,Missense,0.061939541585395,FUNC
17,A,T,p.A17T,Missense,-0.329703976204377,FUNC
17,A,P,p.A17P,Missense,-2.8798217378467,LOF
17,A,S,p.A17S,Missense,0.244995540364458,FUNC
17,A,D,p.A17D,Missense,0.0908070667072376,FUNC
17,A,G,p.A17G,Missense,-0.180847973262728,FUNC
17,A,V,p.A17V,Missense,-0.677930244801608,FUNC
17,A,A,p.A17=,Synonymous,-0.0541470184485822,FUNC
17,A,A,p.A17=,Synonymous,0.495880358483272,FUNC
17,A,A,p.A17=,Synonymous,-0.0510314099344127,FUNC
18,M,L,p.M18L,Missense,-0.0617858138271981,FUNC
18,M,V,p.M18V,Missense,-0.947284908003992,INT
18,M,L,p.M18L,Missense,-0.0567890448928917,FUNC
18,M,K,p.M18K,Missense,-2.39048069455324,LOF
18,M,T,p.M18T,Missense,-1.88743016250199,LOF
18,M,R,p.M18R,Missense,-2.44598808427358,LOF
18,M,I,p.M18I,Missense,-0.288552682219596,FUNC
18,M,I,p.M18I,Missense,-0.160921304812782,FUNC
18,M,I,p.M18I,Missense,-0.193845986770455,FUNC
19,Q,K,p.Q19K,Missense,-0.308824720869346,FUNC
19,Q,E,p.Q19E,Missense,-0.170930864062617,FUNC
19,Q,*,p.Q19*,Nonsense,-1.84113586609137,LOF
19,Q,P,p.Q19P,Missense,-2.16905784149199,LOF
19,Q,R,p.Q19R,Missense,0.0502988982912768,FUNC
19,Q,L,p.Q19L,Missense,-0.0170689180808018,FUNC
19,Q,Q,p.Q19=,Synonymous,-0.117545478556847,FUNC
19,Q,H,p.Q19H,Missense,-0.194105101374487,FUNC
19,Q,H,p.Q19H,Missense,-0.509053283219051,FUNC
20,K,Q,p.K20Q,Missense,-0.780493804051044,INT
20,K,E,p.K20E,Missense,-0.419304746954729,FUNC
20,K,*,p.K20*,Nonsense,-2.20929567342254,LOF
20,K,T,p.K20T,Missense,-0.222575795360717,FUNC
20,K,R,p.K20R,Missense,-0.076775943203518,FUNC
20,K,I,p.K20I,Missense,-0.207838344811351,FUNC
20,K,N,p.K20N,Missense,-0.360313135753224,FUNC
20,K,K,p.K20=,Synonymous,0.119817297801682,FUNC
20,K,N,p.K20N,Missense,-0.340886802751699,FUNC
21,I,L,p.I21L,Missense,0.244697521338296,FUNC
21,I,V,p.I21V,Missense,-0.147346078310098,FUNC
21,I,F,p.I21F,Missense,-0.432698516452122,FUNC
21,I,N,p.I21N,Missense,-0.215462980393704,FUNC
21,I,T,p.I21T,Missense,0.0726212923152069,FUNC
21,I,S,p.I21S,Missense,0.202374414236054,FUNC
21,I,I,p.I21=,Synonymous,-0.582372259854102,FUNC
21,I,M,p.I21M,Missense,-0.527949051398302,FUNC
21,I,I,p.I21=,Synonymous,-1.60156685165604,LOF
22,L,I,p.L22I,Missense,-0.625778259428958,FUNC
22,L,L,p.L22=,Synonymous,0.23403085539082,FUNC
22,L,V,p.L22V,Missense,-0.263422078603365,FUNC
22,L,*,p.L22*,Nonsense,-1.96141420301698,LOF
22,L,S,p.L22S,Missense,-2.10667578876765,LOF
22,L,*,p.L22*,Nonsense,-2.17809513750892,LOF
22,L,F,p.L22F,Missense,-0.33315091053469,FUNC
22,L,L,p.L22=,Synonymous,0.433218113421171,FUNC
22,L,F,p.L22F,Missense,-0.7019804360656,FUNC
23,E,K,p.E23K,Missense,-0.342968970516733,FUNC
23,E,Q,p.E23Q,Missense,0.252641450491044,FUNC
23,E,*,p.E23*,Nonsense,-2.10231492900379,LOF
23,E,A,p.E23A,Missense,-0.608742915773584,FUNC
23,E,G,p.E23G,Missense,-0.843385010197707,INT
23,E,V,p.E23V,Missense,0.135861256938137,FUNC
23,E,E,p.E23=,Synonymous,-0.138161229825439,FUNC
23,E,D,p.E23D,Missense,-1.0667011016788,INT
23,E,D,p.E23D,Missense,-0.873206893106045,INT
24,C,S,p.C24S,Missense,-1.49833581960485,LOF
24,C,R,p.C24R,Missense,-2.78523997945063,LOF
24,C,G,p.C24G,Missense,-2.31508727898479,LOF
24,C,Y,p.C24Y,Missense,-2.14268375955679,LOF
24,C,S,p.C24S,Missense,-1.88032705628737,LOF
24,C,F,p.C24F,Missense,-1.27827379877892,INT
24,C,*,p.C24*,Nonsense,-2.31090766616382,LOF
24,C,C,p.C24=,Synonymous,0.263497775536314,FUNC
24,C,W,p.C24W,Missense,-2.73591085460351,LOF
25,P,T,p.P25T,Missense,-0.194290415479458,FUNC
25,P,A,p.P25A,Missense,0.437601909411023,FUNC
25,P,S,p.P25S,Missense,0.0528508335643715,FUNC
25,P,R,p.P25R,Missense,-0.202953504790366,FUNC
25,P,L,p.P25L,Missense,-1.66083571915168,LOF
26,I,L,p.I26L,Missense,-0.834112338192994,INT
26,I,V,p.I26V,Missense,-0.0102689630162162,FUNC
26,I,N,p.I26N,Missense,-1.98754345492074,LOF
26,I,T,p.I26T,Missense,-1.90767384270355,LOF
26,I,S,p.I26S,Missense,-1.09662949657375,INT
26,I,I,p.I26=,Splice region,0.327747553829515,FUNC
26,I,M,p.I26M,Missense,0.0759306605696321,FUNC
26,I,I,p.I26=,Splice region,0.368261301580362,FUNC
27,C,S,p.C27S,Missense,-1.98032006467426,LOF
27,C,R,p.C27R,Missense,-1.9593567536422,LOF
27,C,G,p.C27G,Missense,-2.37420947167817,LOF
27,C,Y,p.C27Y,Missense,-1.88826243338375,LOF
27,C,S,p.C27S,Missense,-1.60474960199762,LOF
27,C,F,p.C27F,Missense,-2.58012439856074,LOF
27,C,*,p.C27*,Nonsense,-2.2733662951222,LOF
27,C,C,p.C27=,Splice region,0.00326038137182938,FUNC
27,C,W,p.C27W,Missense,-1.92289035894222,LOF
28,L,M,p.L28M,Missense,-0.559160152972987,FUNC
28,L,V,p.L28V,Missense,-0.728959633849956,FUNC
28,L,L,p.L28=,Splice region,-0.165536040911456,FUNC
28,L,Q,p.L28Q,Missense,-0.333171449122507,FUNC
28,L,P,p.L28P,Missense,-1.64360581860877,LOF
28,L,R,p.L28R,Missense,-0.0662809136557019,FUNC
28,L,L,p.L28=,Synonymous,-0.185296967330991,FUNC
28,L,L,p.L28=,Synonymous,-0.067164439050108,FUNC
28,L,L,p.L28=,Synonymous,-0.414420321633281,FUNC
29,E,K,p.E29K,Missense,-0.645511679301639,FUNC
29,E,Q,p.E29Q,Missense,0.132155294541447,FUNC
29,E,*,p.E29*,Nonsense,-2.23427850286585,LOF
29,E,A,p.E29A,Missense,-0.0536296468335891,FUNC
29,E,G,p.E29G,Missense,-0.286648661729374,FUNC
29,E,V,p.E29V,Missense,-0.26008652576368,FUNC
29,E,E,p.E29=,Synonymous,-0.141286740995721,FUNC
29,E,D,p.E29D,Missense,-0.235879028350896,FUNC
29,E,D,p.E29D,Missense,-0.391405355526356,FUNC
30,L,M,p.L30M,Missense,0.284766431176396,FUNC
30,L,L,p.L30=,Synonymous,0.277923519411741,FUNC
30,L,V,p.L30V,Missense,-0.0473694365930921,FUNC
30,L,*,p.L30*,Nonsense,-2.59470853603584,LOF
30,L,S,p.L30S,Missense,0.0601091190569478,FUNC
30,L,W,p.L30W,Missense,-0.295743493236045,FUNC
30,L,L,p.L30=,Synonymous,-0.353035635217169,FUNC
30,L,F,p.L30F,Missense,-0.095957528287595,FUNC
30,L,F,p.L30F,Missense,-0.856959634383142,INT
31,I,L,p.I31L,Missense,-0.0617831265084275,FUNC
31,I,V,p.I31V,Missense,0.171253179516736,FUNC
31,I,F,p.I31F,Missense,0.266900902703425,FUNC
31,I,N,p.I31N,Missense,-0.828223478693833,INT
31,I,T,p.I31T,Missense,-0.133781446217631,FUNC
31,I,S,p.I31S,Missense,-0.0312365889694355,FUNC
31,I,I,p.I31=,Synonymous,-0.693142536943349,FUNC
31,I,M,p.I31M,Missense,-0.631893111643994,FUNC
31,I,I,p.I31=,Synonymous,-0.24797230919738,FUNC
32,K,Q,p.K32Q,Missense,0.0984339301679147,FUNC
32,K,E,p.K32E,Missense,-0.0877744100664281,FUNC
32,K,*,p.K32*,Nonsense,-2.22612222900539,LOF
32,K,T,p.K32T,Missense,0.118786033752062,FUNC
32,K,R,p.K32R,Missense,0.249218829816441,FUNC
32,K,M,p.K32M,Missense,-0.30742353188671,FUNC
32,K,K,p.K32=,Synonymous,-0.0422090556254549,FUNC
32,K,N,p.K32N,Missense,-0.0915135458113136,FUNC
32,K,N,p.K32N,Missense,-0.368416088905072,FUNC
33,E,K,p.E33K,Missense,-0.412088920545003,FUNC
33,E,Q,p.E33Q,Missense,-0.265285715662975,FUNC
33,E,*,p.E33*,Nonsense,-1.46297134906611,LOF
33,E,A,p.E33A,Missense,-0.362577558915998,FUNC
33,E,G,p.E33G,Missense,-0.944338478668913,INT
33,E,V,p.E33V,Missense,-0.01977025765078,FUNC
33,E,D,p.E33D,Missense,-0.258046591052841,FUNC
33,E,E,p.E33=,Synonymous,0.282275854927706,FUNC
33,E,D,p.E33D,Missense,0.235621950838678,FUNC
34,P,T,p.P34T,Missense,-1.18400047550482,INT
34,P,A,p.P34A,Missense,-0.144485559937016,FUNC
34,P,S,p.P34S,Missense,-1.62390239959227,LOF
34,P,H,p.P34H,Missense,-2.83996435390973,LOF
34,P,R,p.P34R,Missense,-2.04326818228721,LOF
34,P,L,p.P34L,Missense,-1.8679314377921,LOF
34,P,P,p.P34=,Synonymous,-0.233401189769988,FUNC
34,P,P,p.P34=,Synonymous,-0.00301940784605856,FUNC
34,P,P,p.P34=,Synonymous,-0.239059047995225,FUNC
35,V,I,p.V35I,Missense,-0.337374626221253,FUNC
35,V,L,p.V35L,Missense,-0.784489926160633,INT
35,V,F,p.V35F,Missense,-1.23552836047238,INT
35,V,D,p.V35D,Missense,-2.39855882524109,LOF
35,V,A,p.V35A,Missense,-1.44176288661518,LOF
35,V,G,p.V35G,Missense,-2.11113231210402,LOF
35,V,V,p.V35=,Synonymous,0.0788901825602333,FUNC
35,V,V,p.V35=,Synonymous,-0.200206977132496,FUNC
35,V,V,p.V35=,Synonymous,-0.107071246984515,FUNC
36,S,T,p.S36T,Missense,-0.0948374584074106,FUNC
36,S,A,p.S36A,Missense,0.067965072687474,FUNC
37,T,P,p.T37P,Missense,-0.368808462244033,FUNC
37,T,A,p.T37A,Missense,0.114420377883202,FUNC
37,T,S,p.T37S,Missense,-0.0807389990250914,FUNC
37,T,K,p.T37K,Missense,-2.49352324025865,LOF
37,T,R,p.T37R,Missense,-2.48552739594034,LOF
37,T,I,p.T37I,Missense,-0.841830450186673,INT
37,T,T,p.T37=,Synonymous,0.112499118456149,FUNC
37,T,T,p.T37=,Synonymous,0.0216296662104994,FUNC
37,T,T,p.T37=,Synonymous,0.130856463914244,FUNC
38,K,Q,p.K38Q,Missense,0.0442274727921174,FUNC
38,K,E,p.K38E,Missense,-0.0591683644642362,FUNC
38,K,*,p.K38*,Nonsense,-2.21396731176657,LOF
38,K,T,p.K38T,Missense,0.0381219973066482,FUNC
38,K,R,p.K38R,Missense,-0.187628556558442,FUNC
38,K,M,p.K38M,Missense,-0.271030936348293,FUNC
38,K,K,p.K38=,Synonymous,-0.290726687608708,FUNC
38,K,N,p.K38N,Missense,-0.122152502974334,FUNC
38,K,N,p.K38N,Missense,-0.0376756066282157,FUNC
39,C,S,p.C39S,Missense,-1.95875615537077,LOF
39,C,R,p.C39R,Missense,-2.40360904850681,LOF
39,C,G,p.C39G,Missense,-2.22421950186341,LOF
39,C,Y,p.C39Y,Missense,-2.65823961350783,LOF
39,C,S,p.C39S,Missense,-2.23492311623277,LOF
39,C,F,p.C39F,Missense,-2.32092314101715,LOF
39,C,*,p.C39*,Nonsense,-2.20254102711855,LOF
39,C,C,p.C39=,Synonymous,0.0692715808856734,FUNC
39,C,W,p.C39W,Missense,-2.53443021351077,LOF
40,D,N,p.D40N,Missense,-0.0802033634658153,FUNC
40,D,H,p.D40H,Missense,-0.281112570315361,FUNC
40,D,Y,p.D40Y,Missense,-0.376938578091546,FUNC
40,D,A,p.D40A,Missense,-0.119215795539015,FUNC
40,D,G,p.D40G,Missense,0.197450867703389,FUNC
40,D,V,p.D40V,Missense,-0.501412521728141,FUNC
40,D,E,p.D40E,Missense,0.000949463263384367,FUNC
40,D,E,p.D40E,Missense,-0.137867777121563,FUNC
40,D,D,p.D40=,Synonymous,0.103513701163575,FUNC
41,H,N,p.H41N,Missense,-2.29075675621701,LOF
41,H,D,p.H41D,Missense,-2.14174273520893,LOF
41,H,Y,p.H41Y,Missense,-2.02233175261816,LOF
41,H,P,p.H41P,Missense,-2.55981702612402,LOF
41,H,R,p.H41R,Missense,-2.07795707321754,LOF
41,H,L,p.H41L,Missense,-1.77532347459198,LOF
41,H,Q,p.H41Q,Missense,-2.32537855229532,LOF
41,H,Q,p.H41Q,Missense,-2.22696615127865,LOF
41,H,H,p.H41=,Synonymous,-0.108913453782523,FUNC
42,I,L,p.I42L,Missense,0.0717261890913763,FUNC
42,I,V,p.I42V,Missense,0.109884311248167,FUNC
42,I,L,p.I42L,Missense,0.0719718393811408,FUNC
42,I,K,p.I42K,Missense,-0.636488370216393,FUNC
42,I,T,p.I42T,Missense,-0.0757505608216063,FUNC
42,I,R,p.I42R,Missense,-0.550860608650059,FUNC
42,I,I,p.I42=,Synonymous,-0.288888987885139,FUNC
42,I,M,p.I42M,Missense,0.146633898149107,FUNC
42,I,I,p.I42=,Synonymous,0.0594634927079684,FUNC
43,F,I,p.F43I,Missense,-1.16581431512051,INT
43,F,L,p.F43L,Missense,-1.08388238566967,INT
43,F,V,p.F43V,Missense,-1.03847047425694,INT
43,F,Y,p.F43Y,Missense,-0.221090144399722,FUNC
43,F,S,p.F43S,Missense,-1.24099502166333,INT
43,F,C,p.F43C,Missense,-0.768825626651291,INT
43,F,L,p.F43L,Missense,-1.67421223592003,LOF
43,F,F,p.F43=,Synonymous,0.0878675582031953,FUNC
43,F,L,p.F43L,Missense,-1.18188652033692,INT
44,C,S,p.C44S,Missense,-2.38393524527543,LOF
44,C,R,p.C44R,Missense,-2.1978281236014,LOF
44,C,G,p.C44G,Missense,-2.53216823657949,LOF
44,C,Y,p.C44Y,Missense,-2.39797407768976,LOF
44,C,S,p.C44S,Missense,-2.26776054445651,LOF
44,C,F,p.C44F,Missense,-2.54218851428559,LOF
44,C,*,p.C44*,Nonsense,-2.91155523427823,LOF
44,C,W,p.C44W,Missense,-2.30701978041447,LOF
44,C,C,p.C44=,Splice region,-2.0922397932055,LOF
45,K,Q,p.K45Q,Missense,-0.267722266843825,FUNC
45,K,E,p.K45E,Missense,-0.634450233958355,FUNC
45,K,*,p.K45*,Nonsense,-2.17196698826844,LOF
45,K,T,p.K45T,Missense,-0.698344351702248,FUNC
45,K,R,p.K45R,Missense,-0.12650525619479,FUNC
45,K,I,p.K45I,Missense,-2.43580582469355,LOF
45,K,N,p.K45N,Missense,-0.337829370855279,FUNC
45,K,K,p.K45=,Splice region,-0.162758147388726,FUNC
45,K,N,p.K45N,Missense,-0.591244043328417,FUNC
46,F,I,p.F46I,Missense,0.118018541159442,FUNC
46,F,L,p.F46L,Missense,-0.578320565388626,FUNC
46,F,V,p.F46V,Missense,-0.400503796929427,FUNC
46,F,Y,p.F46Y,Missense,-0.354796573911067,FUNC
46,F,S,p.F46S,Missense,0.242754195310461,FUNC
46,F,C,p.F46C,Missense,0.138588778865222,FUNC
46,F,L,p.F46L,Missense,-0.520164143977755,FUNC
46,F,F,p.F46=,Synonymous,-0.0215055382057851,FUNC
46,F,L,p.F46L,Missense,0.172623684038249,FUNC
47,C,S,p.C47S,Missense,-0.899627061095552,INT
47,C,R,p.C47R,Missense,-1.8352960909996,LOF
47,C,G,p.C47G,Missense,-2.43588765836569,LOF
47,C,Y,p.C47Y,Missense,-1.67798334117485,LOF
47,C,S,p.C47S,Missense,-1.92779394441767,LOF
47,C,F,p.C47F,Missense,-1.96017875677391,LOF
47,C,*,p.C47*,Nonsense,-2.14961368609209,LOF
47,C,W,p.C47W,Missense,-2.25668984581652,LOF
47,C,C,p.C47=,Synonymous,-0.0228718964318377,FUNC
48,M,L,p.M48L,Missense,-0.387238184471606,FUNC
48,M,V,p.M48V,Missense,-0.276021452097446,FUNC
48,M,L,p.M48L,Missense,-0.243815473964906,FUNC
48,M,K,p.M48K,Missense,-2.12489333961009,LOF
48,M,T,p.M48T,Missense,-0.0633378478729209,FUNC
48,M,R,p.M48R,Missense,-2.88395689569692,LOF
48,M,I,p.M48I,Missense,0.00474249932370893,FUNC
48,M,I,p.M48I,Missense,0.253188799483833,FUNC
48,M,I,p.M48I,Missense,-0.259442038911394,FUNC
49,L,M,p.L49M,Missense,-0.518552505065359,FUNC
49,L,V,p.L49V,Missense,-0.873863087144116,INT
49,L,L,p.L49=,Synonymous,-0.174894606427413,FUNC
49,L,Q,p.L49Q,Missense,-0.319246701652893,FUNC
49,L,P,p.L49P,Missense,-1.62451858428158,LOF
49,L,R,p.L49R,Missense,-0.696670078643576,FUNC
49,L,L,p.L49=,Synonymous,0.0475355105844232,FUNC
49,L,L,p.L49=,Synonymous,-0.0882332524960653,FUNC
49,L,L,p.L49=,Synonymous,-0.617226485292004,FUNC
50,K,Q,p.K50Q,Missense,-0.289487269218209,FUNC
50,K,E,p.K50E,Missense,-0.591419464744108,FUNC
50,K,*,p.K50*,Nonsense,-1.97943299782933,LOF
50,K,T,p.K50T,Missense,0.439789899830432,FUNC
50,K,R,p.K50R,Missense,0.134461516798949,FUNC
50,K,I,p.K50I,Missense,0.126243711985096,FUNC
50,K,N,p.K50N,Missense,0.00854466499037725,FUNC
50,K,K,p.K50=,Synonymous,0.0431611457065616,FUNC
50,K,N,p.K50N,Missense,-0.253562359007247,FUNC
51,L,I,p.L51I,Missense,-0.3213004961115,FUNC
51,L,V,p.L51V,Missense,-0.459830957353929,FUNC
51,L,F,p.L51F,Missense,-0.145244780755562,FUNC
51,L,H,p.L51H,Missense,0.0243776805780889,FUNC
51,L,P,p.L51P,Missense,-1.33284833119727,LOF
51,L,R,p.L51R,Missense,-0.334968954525271,FUNC
51,L,L,p.L51=,Synonymous,0.113099446402535,FUNC
51,L,L,p.L51=,Synonymous,-0.0323270857072348,FUNC
51,L,L,p.L51=,Synonymous,0.211401368413964,FUNC
52,L,I,p.L52I,Missense,-0.219703422173857,FUNC
52,L,V,p.L52V,Missense,-0.105063687593426,FUNC
52,L,F,p.L52F,Missense,-0.164703074148804,FUNC
52,L,H,p.L52H,Missense,-1.01784125726376,INT
52,L,P,p.L52P,Missense,-1.26354747579423,INT
52,L,R,p.L52R,Missense,-1.10919468982921,INT
52,L,L,p.L52=,Synonymous,-0.250111810276369,FUNC
52,L,L,p.L52=,Synonymous,-0.70660026479075,FUNC
52,L,L,p.L52=,Synonymous,-0.143739543394479,FUNC
53,N,H,p.N53H,Missense,0.00649721086311948,FUNC
53,N,D,p.N53D,Missense,-0.52784334974704,FUNC
53,N,Y,p.N53Y,Missense,-0.347396708144995,FUNC
53,N,T,p.N53T,Missense,-0.761628844182999,INT
53,N,S,p.N53S,Missense,0.0078660699987904,FUNC
53,N,I,p.N53I,Missense,-0.347808014969657,FUNC
53,N,K,p.N53K,Missense,-0.803382471314517,INT
53,N,K,p.N53K,Missense,-0.234211060471889,FUNC
53,N,N,p.N53=,Synonymous,-0.466477353956455,FUNC
54,Q,K,p.Q54K,Missense,-0.620201371008806,FUNC
54,Q,E,p.Q54E,Missense,-0.314001650399221,FUNC
54,Q,*,p.Q54*,Nonsense,-2.41053919077601,LOF
54,Q,P,p.Q54P,Missense,-0.475637295642705,FUNC
54,Q,R,p.Q54R,Missense,-0.122193843218794,FUNC
54,Q,L,p.Q54L,Missense,-0.159398532497638,FUNC
54,Q,Q,p.Q54=,Synonymous,-0.308065086485694,FUNC
54,Q,H,p.Q54H,Missense,-0.179248266571474,FUNC
54,Q,H,p.Q54H,Missense,0.0169151611306388,FUNC
55,K,Q,p.K55Q,Missense,0.139050270844548,FUNC
55,K,E,p.K55E,Missense,0.0384727360991774,FUNC
55,K,*,p.K55*,Nonsense,-2.17203562897635,LOF
55,K,T,p.K55T,Missense,0.113378349195662,FUNC
55,K,R,p.K55R,Missense,-0.0416730197266743,FUNC
55,K,M,p.K55M,Missense,-0.132292328183489,FUNC
55,K,K,p.K55=,Synonymous,0.00088168770375378,FUNC
55,K,N,p.K55N,Missense,-0.272475962871033,FUNC
55,K,N,p.K55N,Missense,0.0127625313699572,FUNC
56,K,Q,p.K56Q,Missense,0.2029239245959,FUNC
56,K,E,p.K56E,Missense,-0.0931926781859281,FUNC
56,K,*,p.K56*,Nonsense,-2.2368779276286,LOF
56,K,T,p.K56T,Missense,-0.0828118586184817,FUNC
56,K,R,p.K56R,Missense,-0.0765591154080292,FUNC
56,K,I,p.K56I,Missense,0.141884635048446,FUNC
56,K,N,p.K56N,Missense,-0.194643338444786,FUNC
56,K,K,p.K56=,Synonymous,-0.0728887975583392,FUNC
56,K,N,p.K56N,Missense,-0.0831707430270813,FUNC
57,G,R,p.G57R,Missense,-0.0672533050726693,FUNC
57,G,A,p.G57A,Missense,0.170740039522394,FUNC
57,G,V,p.G57V,Missense,0.0529491582602572,FUNC
58,P,T,p.P58T,Missense,-0.274594395313991,FUNC
58,P,A,p.P58A,Missense,-0.0643034671740271,FUNC
58,P,H,p.P58H,Missense,-1.46809657233464,LOF
58,P,R,p.P58R,Missense,0.191628628089573,FUNC
58,P,L,p.P58L,Missense,0.0336589795354355,FUNC
58,P,P,p.P58=,Synonymous,-0.18016969669255,FUNC
58,P,P,p.P58=,Synonymous,0.0493089202813866,FUNC
58,P,P,p.P58=,Synonymous,0.316611401199192,FUNC
59,S,T,p.S59T,Missense,-0.00769841192752851,FUNC
59,S,P,p.S59P,Missense,-0.111088432294323,FUNC
59,S,A,p.S59A,Missense,0.12259162117247,FUNC
59,S,*,p.S59*,Nonsense,-2.76005221647416,LOF
59,S,*,p.S59*,Nonsense,-2.54562286725908,LOF
59,S,L,p.S59L,Missense,-0.216694820470431,FUNC
59,S,S,p.S59=,Synonymous,0.121022114943972,FUNC
59,S,S,p.S59=,Synonymous,0.207847351602975,FUNC
59,S,S,p.S59=,Synonymous,0.0687942352064083,FUNC
60,Q,K,p.Q60K,Missense,-0.34385436614943,FUNC
60,Q,E,p.Q60E,Missense,0.0746808855832064,FUNC
60,Q,*,p.Q60*,Nonsense,-1.64527533037193,LOF
60,Q,P,p.Q60P,Missense,0.557264663349988,FUNC
60,Q,R,p.Q60R,Missense,0.175006538244498,FUNC
60,Q,L,p.Q60L,Missense,-0.0404271939529918,FUNC
60,Q,Q,p.Q60=,Synonymous,0.250657795066714,FUNC
60,Q,H,p.Q60H,Missense,-0.447215321601555,FUNC
60,Q,H,p.Q60H,Missense,-0.204028150696414,FUNC
61,C,S,p.C61S,Missense,-1.8410356521443,LOF
61,C,R,p.C61R,Missense,-1.32753822709513,INT
61,C,G,p.C61G,Missense,-1.73834813947418,LOF
61,C,Y,p.C61Y,Missense,-1.48851829809458,LOF
61,C,S,p.C61S,Missense,-2.06526710687929,LOF
61,C,F,p.C61F,Missense,-1.93751901318034,LOF
61,C,*,p.C61*,Nonsense,-1.52353474657152,LOF
61,C,C,p.C61=,Synonymous,0.00310022860264836,FUNC
61,C,W,p.C61W,Missense,-2.51201063792508,LOF
62,P,T,p.P62T,Missense,-1.06763515240375,INT
62,P,A,p.P62A,Missense,-0.625469855225993,FUNC
62,P,S,p.P62S,Missense,-0.739621387283442,FUNC
62,P,H,p.P62H,Missense,-0.753698183186401,INT
62,P,R,p.P62R,Missense,-0.73045276973931,FUNC
62,P,L,p.P62L,Missense,-0.530946091433252,FUNC
62,P,P,p.P62=,Synonymous,0.112128585365855,FUNC
62,P,P,p.P62=,Synonymous,0.168528528017527,FUNC
62,P,P,p.P62=,Synonymous,0.015503965969267,FUNC
63,L,I,p.L63I,Missense,0.393837055073655,FUNC
63,L,L,p.L63=,Synonymous,0.530164727718434,FUNC
63,L,V,p.L63V,Missense,0.0815141885627965,FUNC
63,L,*,p.L63*,Nonsense,-2.76247796245549,LOF
63,L,S,p.L63S,Missense,0.0491777349469777,FUNC
63,L,*,p.L63*,Nonsense,-2.11447679323774,LOF
63,L,F,p.L63F,Missense,-0.331791871917996,FUNC
63,L,L,p.L63=,Synonymous,-0.0634543091247518,FUNC
63,L,F,p.L63F,Missense,-0.448007201792022,FUNC
64,C,S,p.C64S,Missense,-2.39036930414511,LOF
64,C,R,p.C64R,Missense,-1.69111599683788,LOF
64,C,G,p.C64G,Missense,-1.95113526060798,LOF
64,C,Y,p.C64Y,Missense,-2.05029821109945,LOF
64,C,S,p.C64S,Missense,-3.02220614509521,LOF
64,C,F,p.C64F,Missense,-1.5894609474847,LOF
64,C,*,p.C64*,Nonsense,-1.58434944755682,LOF
64,C,C,p.C64=,Synonymous,-0.0659024018271285,FUNC
64,C,W,p.C64W,Missense,-1.60379971496205,LOF
65,K,Q,p.K65Q,Missense,0.203499910028996,FUNC
65,K,E,p.K65E,Missense,-0.0104009260486012,FUNC
65,K,*,p.K65*,Nonsense,-1.91699414708455,LOF
65,K,T,p.K65T,Missense,-0.0847304380898753,FUNC
65,K,R,p.K65R,Missense,0.186615867380227,FUNC
65,K,M,p.K65M,Missense,0.19570535930609,FUNC
65,K,K,p.K65=,Synonymous,-0.0110290991647158,FUNC
65,K,N,p.K65N,Missense,-0.356633664203698,FUNC
65,K,N,p.K65N,Missense,-0.266965751909426,FUNC
66,N,H,p.N66H,Missense,0.144133797435321,FUNC
66,N,D,p.N66D,Missense,-0.117274997254614,FUNC
66,N,Y,p.N66Y,Missense,-1.76977311391765,LOF
66,N,T,p.N66T,Missense,0.157001707363151,FUNC
66,N,S,p.N66S,Missense,0.0209716387913158,FUNC
66,N,I,p.N66I,Missense,0.354824787497088,FUNC
66,N,K,p.N66K,Missense,0.331522622481848,FUNC
66,N,N,p.N66=,Synonymous,0.19173596156769,FUNC
66,N,K,p.N66K,Missense,0.0558460249365613,FUNC
67,D,N,p.D67N,Missense,0.149696615854813,FUNC
67,D,H,p.D67H,Missense,-0.336806341430567,FUNC
67,D,Y,p.D67Y,Missense,-0.0809950046543564,FUNC
67,D,A,p.D67A,Missense,0.134788632276109,FUNC
67,D,G,p.D67G,Missense,0.0456568383840613,FUNC
67,D,V,p.D67V,Missense,0.141412315907018,FUNC
67,D,E,p.D67E,Missense,0.259751854132552,FUNC
67,D,D,p.D67=,Synonymous,0.283781640312844,FUNC
67,D,E,p.D67E,Missense,-0.096183037628413,FUNC
68,I,L,p.I68L,Missense,-0.0510104007096042,FUNC
68,I,V,p.I68V,Missense,0.0618273051239322,FUNC
68,I,L,p.I68L,Missense,0.0364445780401083,FUNC
68,I,K,p.I68K,Missense,-1.53542040040805,LOF
68,I,T,p.I68T,Missense,-0.318205181442809,FUNC
68,I,R,p.I68R,Missense,-1.75484824206991,LOF
68,I,I,p.I68=,Synonymous,0.283343238237717,FUNC
68,I,M,p.I68M,Missense,0.122549115399585,FUNC
68,I,I,p.I68=,Synonymous,-0.463256348022372,FUNC
69,T,P,p.T69P,Missense,-0.0274548290858105,FUNC
69,T,A,p.T69A,Missense,-0.0784790276646692,FUNC
69,T,S,p.T69S,Missense,0.117239498010038,FUNC
69,T,N,p.T69N,Missense,0.153279183571519,FUNC
69,T,S,p.T69S,Missense,-0.201005025579741,FUNC
69,T,I,p.T69I,Missense,-0.00286096186449752,FUNC
69,T,T,p.T69=,Synonymous,-0.265930540653985,FUNC
69,T,T,p.T69=,Synonymous,0.484013058028516,FUNC
69,T,T,p.T69=,Synonymous,-0.145479819295588,FUNC
70,K,Q,p.K70Q,Missense,-0.107747823653866,FUNC
70,K,E,p.K70E,Missense,0.124200640270682,FUNC
70,K,*,p.K70*,Nonsense,-2.01837708299856,LOF
70,K,T,p.K70T,Missense,-0.301242803029983,FUNC
70,K,R,p.K70R,Missense,0.207178467164642,FUNC
70,K,I,p.K70I,Missense,-0.101003658796787,FUNC
70,K,N,p.K70N,Missense,0.196738427263807,FUNC
70,K,K,p.K70=,Splice region,0.258460175400767,FUNC
70,K,N,p.K70N,Missense,-1.59083463467556,LOF
71,R,R,p.R71=,Splice region,-2.02421910246939,LOF
71,R,G,p.R71G,Missense,-1.49271759046098,LOF
71,R,W,p.R71W,Missense,-1.82052718089792,LOF
71,R,K,p.R71K,Missense,-2.14933911864244,LOF
71,R,T,p.R71T,Missense,-2.02887064970573,LOF
71,R,M,p.R71M,Missense,-1.71773602920031,LOF
71,R,R,p.R71=,Splice region,-0.0858681228084037,FUNC
71,R,S,p.R71S,Missense,-2.48455100444836,LOF
71,R,S,p.R71S,Missense,-2.40516553009356,LOF
72,S,R,p.S72R,Missense,-0.730647966043399,FUNC
72,S,G,p.S72G,Missense,0.136704721683983,FUNC
72,S,C,p.S72C,Missense,-0.639043379679634,FUNC
72,S,N,p.S72N,Missense,-1.3751642059833,LOF
72,S,T,p.S72T,Missense,0.143507753348203,FUNC
72,S,I,p.S72I,Missense,-1.01387392358275,INT
72,S,R,p.S72R,Missense,-0.637529802865943,FUNC
72,S,R,p.S72R,Missense,-0.542614319238953,FUNC
72,S,S,p.S72=,Synonymous,0.415867158368367,FUNC
73,L,V,p.L73V,Missense,-0.652753444997824,FUNC
73,L,L,p.L73=,Synonymous,-0.316193003238634,FUNC
73,L,Q,p.L73Q,Missense,-1.94479993958441,LOF
73,L,P,p.L73P,Missense,-0.652277126099646,FUNC
73,L,R,p.L73R,Missense,-2.28856407142553,LOF
73,L,L,p.L73=,Synonymous,-0.490375070832333,FUNC
73,L,L,p.L73=,Synonymous,0.474124268060278,FUNC
73,L,L,p.L73=,Synonymous,-0.322502678994144,FUNC
74,Q,K,p.Q74K,Missense,-0.776106133799761,INT
74,Q,E,p.Q74E,Missense,-0.672932131116281,FUNC
74,Q,*,p.Q74*,Nonsense,-2.35601982432529,LOF
74,Q,P,p.Q74P,Missense,-0.690148413898795,FUNC
74,Q,R,p.Q74R,Missense,-0.734980797060967,FUNC
74,Q,L,p.Q74L,Missense,-0.900383530131995,INT
74,Q,H,p.Q74H,Missense,0.219999716132539,FUNC
74,Q,H,p.Q74H,Missense,-0.175679581883847,FUNC
75,E,K,p.E75K,Missense,-0.192425398734912,FUNC
75,E,Q,p.E75Q,Missense,-0.972859688990751,INT
75,E,*,p.E75*,Nonsense,-2.17737659841176,LOF
75,E,A,p.E75A,Missense,0.542069101202301,FUNC
75,E,G,p.E75G,Missense,-0.17249934444057,FUNC
75,E,D,p.E75D,Missense,0.328566194465033,FUNC
75,E,E,p.E75=,Synonymous,-0.0599426746990719,FUNC
75,E,D,p.E75D,Missense,-0.363926141320978,FUNC
76,S,R,p.S76R,Missense,-0.295963198231347,FUNC
76,S,G,p.S76G,Missense,0.844991185551513,FUNC
76,S,C,p.S76C,Missense,0.569152614871201,FUNC
76,S,N,p.S76N,Missense,-0.0412978865249002,FUNC
76,S,T,p.S76T,Missense,-0.208435665910182,FUNC
76,S,I,p.S76I,Missense,-0.789885621808096,INT
76,S,R,p.S76R,Missense,-0.208763266972139,FUNC
76,S,S,p.S76=,Synonymous,-0.115325522207182,FUNC
77,T,P,p.T77P,Missense,-0.631381943627024,FUNC
77,T,A,p.T77A,Missense,0.298169169262425,FUNC
77,T,S,p.T77S,Missense,0.158595847781077,FUNC
77,T,K,p.T77K,Missense,-0.224951976849503,FUNC
77,T,R,p.T77R,Missense,-0.70855680460578,FUNC
77,T,M,p.T77M,Missense,-0.480636068670774,FUNC
77,T,T,p.T77=,Synonymous,0.403068283914335,FUNC
77,T,T,p.T77=,Synonymous,-1.9073097340339,LOF
78,R,R,p.R78=,Synonymous,-0.217289467809529,FUNC
78,R,G,p.R78G,Missense,-0.511506312043328,FUNC
78,R,*,p.R78*,Nonsense,-2.25852006898774,LOF
78,R,K,p.R78K,Missense,-0.592758779863114,FUNC
78,R,T,p.R78T,Missense,-0.311143921023994,FUNC
78,R,I,p.R78I,Missense,-0.631862977302534,FUNC
78,R,S,p.R78S,Missense,-0.626282476489982,FUNC
78,R,R,p.R78=,Synonymous,-0.462861846871384,FUNC
78,R,S,p.R78S,Missense,0.263859171410713,FUNC
79,F,L,p.F79L,Missense,-0.30018783974369,FUNC
79,F,V,p.F79V,Missense,-0.682545605568804,FUNC
79,F,Y,p.F79Y,Missense,-0.129085695153203,FUNC
79,F,S,p.F79S,Missense,-0.648302224583294,FUNC
79,F,C,p.F79C,Missense,-0.194974239294707,FUNC
79,F,L,p.F79L,Missense,0.0545034602353462,FUNC
79,F,F,p.F79=,Synonymous,-0.43586971318449,FUNC
79,F,L,p.F79L,Missense,-0.527933398173203,FUNC
80,S,R,p.S80R,Missense,-0.763797379784919,INT
80,S,G,p.S80G,Missense,0.141974945502884,FUNC
80,S,C,p.S80C,Missense,-0.217631402764945,FUNC
80,S,N,p.S80N,Missense,-0.412347791316904,FUNC
80,S,T,p.S80T,Missense,-0.0687803847504314,FUNC
80,S,I,p.S80I,Missense,-1.40865628664127,LOF
80,S,R,p.S80R,Missense,-0.953367287444341,INT
80,S,S,p.S80=,Synonymous,-0.0221961794474592,FUNC
80,S,R,p.S80R,Missense,-0.364896856122187,FUNC
81,Q,K,p.Q81K,Missense,-0.00691769960713148,FUNC
81,Q,E,p.Q81E,Missense,-0.964109618177198,INT
81,Q,*,p.Q81*,Nonsense,-1.29548719112128,INT
81,Q,P,p.Q81P,Missense,-0.637299098563328,FUNC
81,Q,R,p.Q81R,Missense,0.198078810911722,FUNC
81,Q,L,p.Q81L,Missense,-0.372554913707786,FUNC
81,Q,H,p.Q81H,Missense,-0.784971029092428,INT
81,Q,Q,p.Q81=,Synonymous,0.664720742043957,FUNC
81,Q,H,p.Q81H,Missense,-1.39426952397413,LOF
82,L,I,p.L82I,Missense,0.0263481686460058,FUNC
82,L,V,p.L82V,Missense,-0.788895725099636,INT
82,L,F,p.L82F,Missense,-1.79948636614858,LOF
82,L,H,p.L82H,Missense,-3.50091996986558,LOF
82,L,P,p.L82P,Missense,-3.45179064058583,LOF
82,L,R,p.L82R,Missense,-2.50965929019891,LOF
82,L,L,p.L82=,Synonymous,-0.633264694668249,FUNC
82,L,L,p.L82=,Synonymous,-0.339909779376945,FUNC
82,L,L,p.L82=,Synonymous,0.0116235522653319,FUNC
83,V,I,p.V83I,Missense,-0.0934321813016914,FUNC
83,V,L,p.V83L,Missense,-0.515313480092208,FUNC
83,V,F,p.V83F,Missense,-1.74436152856929,LOF
83,V,D,p.V83D,Missense,-2.37861197619797,LOF
83,V,G,p.V83G,Missense,-0.0206654911150037,FUNC
83,V,V,p.V83=,Synonymous,-0.0984290076375374,FUNC
83,V,V,p.V83=,Synonymous,0.101222782774124,FUNC
83,V,V,p.V83=,Synonymous,0.196945031387954,FUNC
84,E,K,p.E84K,Missense,-1.41519405273807,LOF
84,E,Q,p.E84Q,Missense,0.227577933485268,FUNC
84,E,*,p.E84*,Nonsense,-3.78174671984507,LOF
84,E,A,p.E84A,Missense,-0.43615651271743,FUNC
84,E,G,p.E84G,Missense,0.0977008263695057,FUNC
84,E,V,p.E84V,Missense,-1.57828897095556,LOF
84,E,D,p.E84D,Missense,-0.132410449618805,FUNC
84,E,E,p.E84=,Synonymous,0.0229583115540455,FUNC
84,E,D,p.E84D,Missense,-0.357980559719453,FUNC
85,E,K,p.E85K,Missense,-3.71822115320077,LOF
85,E,Q,p.E85Q,Missense,0.596518163597174,FUNC
85,E,*,p.E85*,Nonsense,-2.93066522055971,LOF
85,E,A,p.E85A,Missense,-0.437781653954811,FUNC
85,E,G,p.E85G,Missense,-1.45571882702139,LOF
85,E,V,p.E85V,Missense,-0.100970759765058,FUNC
85,E,E,p.E85=,Synonymous,0.165827386507889,FUNC
85,E,D,p.E85D,Missense,-0.772470137838265,INT
85,E,D,p.E85D,Missense,-0.326985961469278,FUNC
86,L,I,p.L86I,Missense,-0.199917549426923,FUNC
86,L,V,p.L86V,Missense,-0.605664748165032,FUNC
86,L,L,p.L86=,Synonymous,0.0185765635524308,FUNC
86,L,Q,p.L86Q,Missense,-0.563689704420925,FUNC
86,L,P,p.L86P,Missense,-1.99644566293025,LOF
86,L,R,p.L86R,Missense,-3.33011680009725,LOF
86,L,L,p.L86=,Synonymous,-0.74475641789617,FUNC
86,L,L,p.L86=,Synonymous,-0.357514832123384,FUNC
86,L,L,p.L86=,Synonymous,0.170430124815421,FUNC
87,L,M,p.L87M,Missense,-0.436587615023912,FUNC
87,L,L,p.L87=,Synonymous,-0.075085123021708,FUNC
87,L,V,p.L87V,Missense,-0.334476341743134,FUNC
87,L,*,p.L87*,Nonsense,-1.97791548004045,LOF
87,L,S,p.L87S,Missense,0.00365699724177147,FUNC
87,L,W,p.L87W,Missense,-0.21889029260242,FUNC
87,L,L,p.L87=,Synonymous,-2.27150633609115,LOF
87,L,F,p.L87F,Missense,-0.139688848800258,FUNC
87,L,F,p.L87F,Missense,-2.19093104198801,LOF
88,K,Q,p.K88Q,Missense,-0.404258963159923,FUNC
88,K,E,p.K88E,Missense,0.223227493922057,FUNC
88,K,*,p.K88*,Nonsense,-2.31537290913289,LOF
88,K,T,p.K88T,Missense,-0.110824204974069,FUNC
88,K,R,p.K88R,Missense,-0.194855836414978,FUNC
88,K,N,p.K88N,Missense,-0.605310021034968,FUNC
88,K,K,p.K88=,Synonymous,-0.555066744711787,FUNC
88,K,N,p.K88N,Missense,0.1898640083204,FUNC
89,I,L,p.I89L,Missense,-0.0983238418972658,FUNC
89,I,V,p.I89V,Missense,-0.849261952974786,INT
89,I,F,p.I89F,Missense,-0.315334500208483,FUNC
89,I,N,p.I89N,Missense,-2.58720603093368,LOF
89,I,T,p.I89T,Missense,0.530562189608434,FUNC
89,I,S,p.I89S,Missense,-0.768140526254823,INT
89,I,I,p.I89=,Synonymous,0.479888411258346,FUNC
89,I,M,p.I89M,Missense,-0.275180330692083,FUNC
89,I,I,p.I89=,Synonymous,-0.313942444722845,FUNC
90,I,L,p.I90L,Missense,-0.688819549652649,FUNC
90,I,V,p.I90V,Missense,-0.0722305973971354,FUNC
90,I,F,p.I90F,Missense,-0.225198811916451,FUNC
90,I,N,p.I90N,Missense,-1.13446904179049,INT
90,I,T,p.I90T,Missense,0.0569082533560138,FUNC
90,I,S,p.I90S,Missense,-0.270302363087462,FUNC
90,I,I,p.I90=,Synonymous,-0.661876030887427,FUNC
90,I,I,p.I90=,Synonymous,0.181486994240425,FUNC
90,I,M,p.I90M,Missense,-0.228945552243541,FUNC
91,C,S,p.C91S,Missense,-0.241779426738935,FUNC
91,C,R,p.C91R,Missense,-0.330071693871008,FUNC
91,C,G,p.C91G,Missense,-0.716466544933724,FUNC
91,C,Y,p.C91Y,Missense,0.0363977346007979,FUNC
91,C,S,p.C91S,Missense,-0.624507820509113,FUNC
91,C,F,p.C91F,Missense,-0.243291683738199,FUNC
91,C,*,p.C91*,Nonsense,-1.781887252075,LOF
91,C,C,p.C91=,Synonymous,-0.607694464931807,FUNC
91,C,W,p.C91W,Missense,-0.847753322261413,INT
92,A,T,p.A92T,Missense,-2.26248671914372,LOF
92,A,P,p.A92P,Missense,-3.04366046844681,LOF
92,A,S,p.A92S,Missense,-0.580671009093887,FUNC
92,A,D,p.A92D,Missense,-2.0817542004775,LOF
92,A,G,p.A92G,Missense,-1.29607333854295,INT
92,A,V,p.A92V,Missense,-1.84583327622425,LOF
92,A,A,p.A92=,Synonymous,0.134814492774108,FUNC
92,A,A,p.A92=,Synonymous,0.333620534865433,FUNC
92,A,A,p.A92=,Synonymous,-0.880529146014121,INT
93,F,I,p.F93I,Missense,-0.675617637380368,FUNC
93,F,L,p.F93L,Missense,-1.89808212586787,LOF
93,F,V,p.F93V,Missense,0.13737849788977,FUNC
93,F,Y,p.F93Y,Missense,0.390097775540481,FUNC
93,F,S,p.F93S,Missense,-1.42075827273154,LOF
93,F,C,p.F93C,Missense,-1.15247994178777,INT
93,F,L,p.F93L,Missense,-1.23626441547654,INT
93,F,F,p.F93=,Synonymous,-0.0663049494879567,FUNC
93,F,L,p.F93L,Missense,-2.28309911645289,LOF
94,Q,K,p.Q94K,Missense,-0.195956095141029,FUNC
94,Q,E,p.Q94E,Missense,-0.114305140427472,FUNC
94,Q,*,p.Q94*,Nonsense,-2.69156700599675,LOF
94,Q,P,p.Q94P,Missense,-1.2029044729423,INT
94,Q,R,p.Q94R,Missense,-0.00108641481694379,FUNC
94,Q,L,p.Q94L,Missense,-1.8635581417168,LOF
94,Q,Q,p.Q94=,Synonymous,-0.508034385208526,FUNC
94,Q,H,p.Q94H,Missense,-0.24817916335054,FUNC
94,Q,H,p.Q94H,Missense,-0.439171236353344,FUNC
95,L,I,p.L95I,Missense,-0.0792177393431917,FUNC
95,L,V,p.L95V,Missense,-1.12379030791044,INT
95,L,F,p.L95F,Missense,-0.480312471193396,FUNC
95,L,H,p.L95H,Missense,-0.353218078407646,FUNC
95,L,P,p.L95P,Missense,-3.27129662076606,LOF
95,L,R,p.L95R,Missense,-0.202981727262133,FUNC
95,L,L,p.L95=,Synonymous,-0.3233801698786,FUNC
95,L,L,p.L95=,Synonymous,-0.0214431217050921,FUNC
95,L,L,p.L95=,Synonymous,-0.125593141619068,FUNC
96,D,N,p.D96N,Missense,-3.70116237654448,LOF
96,D,H,p.D96H,Missense,-2.56225645650945,LOF
96,D,Y,p.D96Y,Missense,-3.54409780459629,LOF
96,D,A,p.D96A,Missense,-3.0700093589234,LOF
96,D,G,p.D96G,Missense,-3.00243211698934,LOF
96,D,V,p.D96V,Missense,-2.74340346551776,LOF
96,D,E,p.D96E,Missense,-3.84438142691263,LOF
96,D,E,p.D96E,Missense,-3.46654746230765,LOF
96,D,D,p.D96=,Synonymous,-0.310482960726149,FUNC
97,T,P,p.T97P,Missense,-2.51717085050026,LOF
97,T,A,p.T97A,Missense,-0.726820581088183,FUNC
97,T,S,p.T97S,Missense,-0.334099777232787,FUNC
97,T,K,p.T97K,Missense,-1.27912017674434,INT
97,T,R,p.T97R,Missense,-1.02382358502105,INT
97,T,I,p.T97I,Missense,-1.04013448709355,INT
97,T,T,p.T97=,Synonymous,-0.061786460717952,FUNC
97,T,T,p.T97=,Synonymous,-0.0236277797257578,FUNC
97,T,T,p.T97=,Synonymous,-0.297291972362217,FUNC
98,G,S,p.G98S,Missense,-0.281335101034925,FUNC
98,G,R,p.G98R,Missense,-0.378471486604788,FUNC
98,G,C,p.G98C,Missense,-0.793166242021027,INT
98,G,D,p.G98D,Missense,-0.390340916036396,FUNC
98,G,A,p.G98A,Missense,-0.389790134685555,FUNC
98,G,V,p.G98V,Missense,-1.32926909487839,LOF
98,G,G,p.G98=,Synonymous,-0.0207805062900346,FUNC
98,G,G,p.G98=,Synonymous,-0.17245188980342,FUNC
98,G,G,p.G98=,Synonymous,-0.27863458160642,FUNC
99,L,L,p.L99=,Synonymous,-0.222150724542185,FUNC
99,L,V,p.L99V,Missense,-0.276943465997748,FUNC
100,E,*,p.E100*,Nonsense,-1.95096032372052,LOF
100,E,E,p.E100=,Splice region,-0.355641074519881,FUNC
100,E,D,p.E100D,Missense,-0.360777986077225,FUNC
100,E,D,p.E100D,Missense,-0.377925754341704,FUNC
101,Y,N,p.Y101N,Missense,-0.674152758903757,FUNC
101,Y,D,p.Y101D,Missense,-0.38558587689788,FUNC
1631,S,R,p.S1631R,Missense,0.151486148278599,FUNC
1631,S,G,p.S1631G,Missense,0.305708317472987,FUNC
1631,S,C,p.S1631C,Missense,0.133622446891161,FUNC
1631,S,N,p.S1631N,Missense,-0.610018671719404,FUNC
1631,S,T,p.S1631T,Missense,-0.895747939066079,INT
1631,S,I,p.S1631I,Missense,-1.18083184329798,INT
1631,S,R,p.S1631R,Missense,0.154709037549276,FUNC
1631,S,S,p.S1631=,Synonymous,0.32544200451846,FUNC
1631,S,R,p.S1631R,Missense,-0.475580373315242,FUNC
1632,V,M,p.V1632M,Missense,-0.439777682861633,FUNC
1632,V,L,p.V1632L,Missense,0.0401613569917659,FUNC
1632,V,L,p.V1632L,Missense,-0.794290560797775,INT
1632,V,E,p.V1632E,Missense,0.185324553177342,FUNC
1632,V,A,p.V1632A,Missense,-0.016459956620108,FUNC
1632,V,G,p.V1632G,Missense,-0.554260259698467,FUNC
1632,V,V,p.V1632=,Synonymous,-0.12654834955993,FUNC
1632,V,V,p.V1632=,Synonymous,0.649475135035928,FUNC
1632,V,V,p.V1632=,Synonymous,-1.09541443269547,INT
1633,S,R,p.S1633R,Missense,0.63455728105743,FUNC
1633,S,G,p.S1633G,Missense,-0.252650939571362,FUNC
1633,S,C,p.S1633C,Missense,1.09413831402149,FUNC
1633,S,N,p.S1633N,Missense,-0.122721153018302,FUNC
1633,S,T,p.S1633T,Missense,-0.412856231310871,FUNC
1633,S,I,p.S1633I,Missense,0.0506325537568632,FUNC
1633,S,R,p.S1633R,Missense,-0.555716157713003,FUNC
1633,S,R,p.S1633R,Missense,-1.07040009839147,INT
1633,S,S,p.S1633=,Synonymous,-0.498563473407033,FUNC
1634,R,R,p.R1634=,Synonymous,-0.480590718540609,FUNC
1634,R,G,p.R1634G,Missense,0.519292946630737,FUNC
1634,R,K,p.R1634K,Missense,0.268767598551764,FUNC
1634,R,T,p.R1634T,Missense,0.702940695596464,FUNC
1634,R,S,p.R1634S,Missense,0.448533074401006,FUNC
1634,R,S,p.R1634S,Missense,1.30689208765218,FUNC
1635,E,K,p.E1635K,Missense,0.218818423209644,FUNC
1635,E,Q,p.E1635Q,Missense,-0.312102905354693,FUNC
1635,E,*,p.E1635*,Nonsense,-2.46361808766912,LOF
1635,E,A,p.E1635A,Missense,-0.165063121503346,FUNC
1635,E,G,p.E1635G,Missense,-0.09675439111036,FUNC
1635,E,V,p.E1635V,Missense,-0.113120940141855,FUNC
1635,E,E,p.E1635=,Synonymous,-0.0434182378030501,FUNC
1635,E,D,p.E1635D,Missense,-0.143617494623802,FUNC
1635,E,D,p.E1635D,Missense,-0.524113644543298,FUNC
1636,K,Q,p.K1636Q,Missense,0.4161211536445,FUNC
1636,K,E,p.K1636E,Missense,0.646739007731979,FUNC
1636,K,*,p.K1636*,Nonsense,-1.65689111020017,LOF
1636,K,T,p.K1636T,Missense,0.0119658191805132,FUNC
1636,K,R,p.K1636R,Missense,0.0161859957590262,FUNC
1636,K,M,p.K1636M,Missense,-0.0779957208312601,FUNC
1636,K,K,p.K1636=,Synonymous,0.106967523933618,FUNC
1636,K,N,p.K1636N,Missense,0.0729845101492968,FUNC
1636,K,N,p.K1636N,Missense,0.0498460639049248,FUNC
1637,P,T,p.P1637T,Missense,-0.659918849676847,FUNC
1637,P,A,p.P1637A,Missense,0.271299862621932,FUNC
1637,P,S,p.P1637S,Missense,0.377990216934896,FUNC
1637,P,Q,p.P1637Q,Missense,-0.286928234851148,FUNC
1637,P,R,p.P1637R,Missense,-0.0617558414637228,FUNC
1637,P,L,p.P1637L,Missense,-0.417492856234616,FUNC
1637,P,P,p.P1637=,Synonymous,-0.44758201452048,FUNC
1637,P,P,p.P1637=,Synonymous,0.046603956759305,FUNC
1637,P,P,p.P1637=,Synonymous,-0.0558101655537388,FUNC
1638,E,K,p.E1638K,Missense,-0.425459444399299,FUNC
1638,E,Q,p.E1638Q,Missense,0.209717916059349,FUNC
1638,E,*,p.E1638*,Nonsense,-2.44516415626039,LOF
1638,E,A,p.E1638A,Missense,0.112986175032725,FUNC
1638,E,G,p.E1638G,Missense,-0.191476376634485,FUNC
1638,E,V,p.E1638V,Missense,-0.276578724171495,FUNC
1638,E,D,p.E1638D,Missense,-0.211556712698723,FUNC
1638,E,E,p.E1638=,Synonymous,-0.081573029016585,FUNC
1638,E,D,p.E1638D,Missense,-0.226429280690683,FUNC
1639,L,M,p.L1639M,Missense,-0.129775073620502,FUNC
1639,L,L,p.L1639=,Synonymous,0.278852371883411,FUNC
1639,L,V,p.L1639V,Missense,0.985678871591415,FUNC
1639,L,*,p.L1639*,Nonsense,-2.47139775610019,LOF
1639,L,S,p.L1639S,Missense,0.396995548003964,FUNC
1639,L,W,p.L1639W,Missense,-0.156545823494356,FUNC
1639,L,L,p.L1639=,Synonymous,-0.244878512739614,FUNC
1639,L,F,p.L1639F,Missense,0.593827846591637,FUNC
1639,L,F,p.L1639F,Missense,-0.128654136121499,FUNC
1640,T,P,p.T1640P,Missense,0.331681382815931,FUNC
1640,T,A,p.T1640A,Missense,-0.239408827597538,FUNC
1640,T,S,p.T1640S,Missense,-0.125729668752198,FUNC
1640,T,K,p.T1640K,Missense,0.0368289489980411,FUNC
1640,T,R,p.T1640R,Missense,-0.113288211959227,FUNC
1640,T,I,p.T1640I,Missense,-0.0218986974718469,FUNC
1640,T,T,p.T1640=,Synonymous,-0.866982108554823,INT
1640,T,T,p.T1640=,Synonymous,0.420519149593748,FUNC
1640,T,T,p.T1640=,Synonymous,-0.0416338770173233,FUNC
1641,A,T,p.A1641T,Missense,0.375689477982788,FUNC
1641,A,P,p.A1641P,Missense,-0.287473571368212,FUNC
1641,A,S,p.A1641S,Missense,-0.927134133766101,INT
1641,A,D,p.A1641D,Missense,0.441891174889265,FUNC
1641,A,G,p.A1641G,Missense,-0.288384855999727,FUNC
1641,A,V,p.A1641V,Missense,0.362735801041234,FUNC
1641,A,A,p.A1641=,Synonymous,-0.579607487923384,FUNC
1641,A,A,p.A1641=,Synonymous,-0.152310166719624,FUNC
1641,A,A,p.A1641=,Synonymous,-0.446852361162926,FUNC
1642,S,T,p.S1642T,Missense,0.432342352526231,FUNC
1642,S,P,p.S1642P,Missense,0.460698129790579,FUNC
1642,S,A,p.S1642A,Missense,-0.0488174918282292,FUNC
1642,S,*,p.S1642*,Nonsense,-1.76398026577746,LOF
1642,S,*,p.S1642*,Nonsense,-2.55969184202558,LOF
1642,S,L,p.S1642L,Missense,0.05691160495523,FUNC
1642,S,S,p.S1642=,Synonymous,0.179966509411935,FUNC
1642,S,S,p.S1642=,Synonymous,0.177206358742981,FUNC
1642,S,S,p.S1642=,Synonymous,-0.314387175418668,FUNC
1643,T,P,p.T1643P,Missense,-0.0752181030694236,FUNC
1643,T,A,p.T1643A,Missense,0.124293669243233,FUNC
1643,T,S,p.T1643S,Missense,0.322239809335731,FUNC
1643,T,K,p.T1643K,Missense,-0.159561512429287,FUNC
1643,T,R,p.T1643R,Missense,-0.226536684687024,FUNC
1643,T,I,p.T1643I,Missense,-0.174565420561269,FUNC
1643,T,T,p.T1643=,Synonymous,-0.244007836929304,FUNC
1643,T,T,p.T1643=,Synonymous,0.197019897287456,FUNC
1643,T,T,p.T1643=,Synonymous,-0.0522614651851667,FUNC
1644,E,K,p.E1644K,Missense,-0.195403392966752,FUNC
1644,E,Q,p.E1644Q,Missense,0.288594316318101,FUNC
1644,E,*,p.E1644*,Nonsense,-2.11987891872328,LOF
1644,E,A,p.E1644A,Missense,-0.128459394668549,FUNC
1644,E,G,p.E1644G,Missense,0.0196284986556055,FUNC
1644,E,V,p.E1644V,Missense,-0.0707839355815872,FUNC
1644,E,D,p.E1644D,Missense,-0.382091403652162,FUNC
1644,E,E,p.E1644=,Synonymous,-0.157215427484012,FUNC
1644,E,D,p.E1644D,Missense,0.490304116228315,FUNC
1645,R,R,p.R1645=,Synonymous,-0.0881440661677245,FUNC
1645,R,G,p.R1645G,Missense,0.292396293348761,FUNC
1645,R,W,p.R1645W,Missense,-0.0272239319183476,FUNC
1645,R,K,p.R1645K,Missense,-0.0560751717928809,FUNC
1645,R,T,p.R1645T,Missense,0.134062079199215,FUNC
1645,R,M,p.R1645M,Missense,-0.777459733242668,INT
1645,R,R,p.R1645=,Synonymous,0.402628458911041,FUNC
1645,R,S,p.R1645S,Missense,0.418234041772017,FUNC
1645,R,S,p.R1645S,Missense,-0.592238305140817,FUNC
1646,V,I,p.V1646I,Missense,-0.283400557736232,FUNC
1646,V,L,p.V1646L,Missense,-0.233034711055546,FUNC
1646,V,F,p.V1646F,Missense,-0.455977913237396,FUNC
1646,V,D,p.V1646D,Missense,0.013159575015928,FUNC
1646,V,A,p.V1646A,Missense,0.0527746377112928,FUNC
1646,V,G,p.V1646G,Missense,0.512206875292839,FUNC
1646,V,V,p.V1646=,Synonymous,-2.05929161132806,LOF
1646,V,V,p.V1646=,Synonymous,-0.531218377290016,FUNC
1646,V,V,p.V1646=,Synonymous,-0.913255253694216,INT
1647,N,H,p.N1647H,Missense,0.0625159464282436,FUNC
1647,N,D,p.N1647D,Missense,-0.0950482207060331,FUNC
1647,N,Y,p.N1647Y,Missense,0.269235812766713,FUNC
1647,N,T,p.N1647T,Missense,0.107487390595714,FUNC
1647,N,S,p.N1647S,Missense,0.318003895189966,FUNC
1647,N,I,p.N1647I,Missense,0.0819796222388448,FUNC
1647,N,K,p.N1647K,Missense,-0.114103274322657,FUNC
1647,N,K,p.N1647K,Missense,-0.32522990518979,FUNC
1647,N,N,p.N1647=,Synonymous,-0.140631947684955,FUNC
1648,K,Q,p.K1648Q,Missense,-0.249928580399797,FUNC
1648,K,E,p.K1648E,Missense,0.362390956457154,FUNC
1648,K,*,p.K1648*,Nonsense,-2.0965657786158,LOF
1648,K,T,p.K1648T,Missense,-0.0498654815853825,FUNC
1648,K,R,p.K1648R,Missense,0.00423773889220677,FUNC
1648,K,I,p.K1648I,Missense,0.168571556303487,FUNC
1648,K,N,p.K1648N,Missense,0.111407047399935,FUNC
1648,K,K,p.K1648=,Synonymous,0.0608322291926667,FUNC
1648,K,N,p.K1648N,Missense,0.069540537773731,FUNC
1649,R,R,p.R1649=,Synonymous,0.0449788194465629,FUNC
1649,R,G,p.R1649G,Missense,0.52223165121883,FUNC
1649,R,*,p.R1649*,Nonsense,-1.3512110207618,LOF
1649,R,K,p.R1649K,Missense,0.075178455167008,FUNC
1649,R,T,p.R1649T,Missense,-0.214181107122188,FUNC
1649,R,I,p.R1649I,Missense,0.139303582606878,FUNC
1649,R,S,p.R1649S,Missense,0.208336568294786,FUNC
1649,R,R,p.R1649=,Synonymous,0.400688039837797,FUNC
1649,R,S,p.R1649S,Missense,-0.142793622141707,FUNC
1650,M,L,p.M1650L,Missense,0.00262448634916343,FUNC
1650,M,V,p.M1650V,Missense,0.758384538486132,FUNC
1650,M,L,p.M1650L,Missense,-0.117122550576725,FUNC
1650,M,K,p.M1650K,Missense,0.0816767312422934,FUNC
1650,M,T,p.M1650T,Missense,0.210380627424197,FUNC
1650,M,R,p.M1650R,Missense,0.29272442696826,FUNC
1650,M,I,p.M1650I,Missense,0.204137127032947,FUNC
1650,M,I,p.M1650I,Missense,0.466635213802171,FUNC
1650,M,I,p.M1650I,Missense,0.0934307615143418,FUNC
1651,S,T,p.S1651T,Missense,-0.284494786820242,FUNC
1651,S,P,p.S1651P,Missense,-1.47864870662897,LOF
1651,S,A,p.S1651A,Missense,0.343579957633816,FUNC
1651,S,Y,p.S1651Y,Missense,-0.322341632263223,FUNC
1651,S,C,p.S1651C,Missense,-0.293665510563804,FUNC
1651,S,F,p.S1651F,Missense,-0.631796913930221,FUNC
1651,S,S,p.S1651=,Synonymous,-0.427897212333101,FUNC
1651,S,S,p.S1651=,Synonymous,0.186000304815304,FUNC
1651,S,S,p.S1651=,Synonymous,-0.0879171563617295,FUNC
1652,M,L,p.M1652L,Missense,0.282053158140163,FUNC
1652,M,V,p.M1652V,Missense,0.100098058081626,FUNC
1652,M,L,p.M1652L,Missense,0.321293604260533,FUNC
1652,M,K,p.M1652K,Missense,-1.53235546339967,LOF
1652,M,T,p.M1652T,Missense,-0.353085227277311,FUNC
1652,M,R,p.M1652R,Missense,-1.89050127382734,LOF
1652,M,I,p.M1652I,Missense,0.143488826026886,FUNC
1652,M,I,p.M1652I,Missense,0.11400184816989,FUNC
1652,M,I,p.M1652I,Missense,-0.356594915703969,FUNC
1653,V,L,p.V1653L,Missense,-1.79728425621539,LOF
1653,V,L,p.V1653L,Missense,-1.84913911912845,LOF
1653,V,E,p.V1653E,Missense,-1.50369772175934,LOF
1653,V,A,p.V1653A,Missense,0.171399878329824,FUNC
1653,V,G,p.V1653G,Missense,-0.263024274195196,FUNC
1653,V,V,p.V1653=,Synonymous,-0.0799738358470211,FUNC
1653,V,V,p.V1653=,Synonymous,-0.0239047000885326,FUNC
1653,V,V,p.V1653=,Synonymous,-0.0833417126428698,FUNC
1654,V,M,p.V1654M,Missense,0.0661023502526093,FUNC
1654,V,L,p.V1654L,Missense,0.26836844647293,FUNC
1654,V,L,p.V1654L,Missense,-0.169476902594839,FUNC
1654,V,E,p.V1654E,Missense,-1.06796398552556,INT
1654,V,A,p.V1654A,Missense,0.169871102152978,FUNC
1654,V,G,p.V1654G,Missense,-0.188828197717281,FUNC
1654,V,V,p.V1654=,Synonymous,0.25178800931775,FUNC
1654,V,V,p.V1654=,Synonymous,0.572279396145086,FUNC
1654,V,V,p.V1654=,Synonymous,0.337723210784118,FUNC
1655,S,T,p.S1655T,Missense,-0.666203499709748,FUNC
1655,S,P,p.S1655P,Missense,-1.78250615557211,LOF
1655,S,A,p.S1655A,Missense,-1.13543043295709,INT
1655,S,Y,p.S1655Y,Missense,-2.49788889262217,LOF
1655,S,C,p.S1655C,Missense,-1.53966692235395,LOF
1655,S,F,p.S1655F,Missense,-1.55569687050806,LOF
1655,S,S,p.S1655=,Synonymous,0.770906755941785,FUNC
1655,S,S,p.S1655=,Synonymous,0.596434076519009,FUNC
1655,S,S,p.S1655=,Synonymous,0.319303271390112,FUNC
1656,G,S,p.G1656S,Missense,-0.499145944604371,FUNC
1656,G,R,p.G1656R,Missense,0.135780354183558,FUNC
1656,G,C,p.G1656C,Missense,-0.11177419557439,FUNC
1656,G,D,p.G1656D,Missense,-0.53894391028949,FUNC
1656,G,A,p.G1656A,Missense,0.242313139609143,FUNC
1656,G,V,p.G1656V,Missense,-0.669802369867185,FUNC
1656,G,G,p.G1656=,Synonymous,0.239990054360226,FUNC
1656,G,G,p.G1656=,Synonymous,-0.421132233176648,FUNC
1656,G,G,p.G1656=,Synonymous,0.336415094407682,FUNC
1657,L,M,p.L1657M,Missense,0.0999458907890361,FUNC
1657,L,V,p.L1657V,Missense,0.328690410360229,FUNC
1657,L,L,p.L1657=,Synonymous,0.0408515515637123,FUNC
1657,L,Q,p.L1657Q,Missense,-1.75825127492625,LOF
1657,L,P,p.L1657P,Missense,-1.5261028971258,LOF
1657,L,R,p.L1657R,Missense,-1.64680601907514,LOF
1657,L,L,p.L1657=,Synonymous,0.62740878552526,FUNC
1657,L,L,p.L1657=,Synonymous,0.00855760583454574,FUNC
1657,L,L,p.L1657=,Synonymous,0.248667768373828,FUNC
1658,T,A,p.T1658A,Missense,0.257015714913233,FUNC
1658,T,S,p.T1658S,Missense,0.483314352802721,FUNC
1659,P,T,p.P1659T,Missense,0.629009943195276,FUNC
1659,P,A,p.P1659A,Missense,0.284095809598948,FUNC
1659,P,S,p.P1659S,Missense,0.352563321944432,FUNC
1659,P,Q,p.P1659Q,Missense,0.512326668905202,FUNC
1659,P,R,p.P1659R,Missense,0.133281467463102,FUNC
1659,P,L,p.P1659L,Missense,0.231939078225961,FUNC
1659,P,P,p.P1659=,Synonymous,0.787590995455782,FUNC
1659,P,P,p.P1659=,Synonymous,0.499233424334583,FUNC
1659,P,P,p.P1659=,Synonymous,0.555569347339143,FUNC
1660,E,K,p.E1660K,Missense,-0.630497670304654,FUNC
1660,E,Q,p.E1660Q,Missense,0.16833653906061,FUNC
1660,E,*,p.E1660*,Nonsense,-2.04781856167972,LOF
1660,E,A,p.E1660A,Missense,0.13457731401999,FUNC
1660,E,G,p.E1660G,Missense,0.184538892389117,FUNC
1660,E,V,p.E1660V,Missense,0.0189555278932545,FUNC
1660,E,D,p.E1660D,Missense,-0.11067275527813,FUNC
1660,E,E,p.E1660=,Synonymous,0.391456802132211,FUNC
1660,E,D,p.E1660D,Missense,0.491942061473778,FUNC
1661,E,K,p.E1661K,Missense,-0.311873628943405,FUNC
1661,E,Q,p.E1661Q,Missense,-0.16863073024752,FUNC
1661,E,*,p.E1661*,Nonsense,-1.82974505645471,LOF
1661,E,A,p.E1661A,Missense,-0.58145544401476,FUNC
1661,E,G,p.E1661G,Missense,-0.797023235804783,INT
1661,E,V,p.E1661V,Missense,-0.584913205211459,FUNC
1661,E,D,p.E1661D,Missense,0.10499885309288,FUNC
1661,E,E,p.E1661=,Synonymous,0.215907076730171,FUNC
1661,E,D,p.E1661D,Missense,0.333820624196552,FUNC
1662,F,I,p.F1662I,Missense,0.260322650790343,FUNC
1662,F,L,p.F1662L,Missense,-0.0496224300991557,FUNC
1662,F,V,p.F1662V,Missense,-0.0577000229629312,FUNC
1662,F,Y,p.F1662Y,Missense,0.052872220357304,FUNC
1662,F,S,p.F1662S,Missense,-0.254857537628401,FUNC
1662,F,C,p.F1662C,Missense,0.748164167268976,FUNC
1662,F,L,p.F1662L,Missense,-0.650154023869898,FUNC
1662,F,F,p.F1662=,Splice region,-0.474513967520323,FUNC
1662,F,L,p.F1662L,Missense,0.130331688596487,FUNC
1663,M,L,p.M1663L,Missense,-1.06292469408814,INT
1663,M,V,p.M1663V,Missense,-0.0152466019704292,FUNC
1663,M,L,p.M1663L,Missense,-2.12306699932937,LOF
1663,M,K,p.M1663K,Missense,-2.05232380144043,LOF
1663,M,T,p.M1663T,Missense,-0.8088266943784,INT
1663,M,R,p.M1663R,Missense,-1.93511921709868,LOF
1663,M,I,p.M1663I,Missense,-0.748995161432475,INT
1663,M,I,p.M1663I,Missense,-0.052540096739374,FUNC
1663,M,I,p.M1663I,Missense,-0.404924608574949,FUNC
1664,L,I,p.L1664I,Missense,-0.327476216503233,FUNC
1664,L,V,p.L1664V,Missense,-0.447092426335367,FUNC
1664,L,F,p.L1664F,Missense,0.0472151356560475,FUNC
1664,L,H,p.L1664H,Missense,0.034633748891832,FUNC
1664,L,P,p.L1664P,Missense,-0.0101772242695253,FUNC
1664,L,R,p.L1664R,Missense,-0.521993648241751,FUNC
1664,L,L,p.L1664=,Synonymous,-0.146133623439301,FUNC
1664,L,L,p.L1664=,Synonymous,-1.03368954565127,INT
1665,V,M,p.V1665M,Missense,0.0247687159654046,FUNC
1665,V,L,p.V1665L,Missense,-0.0556632282865001,FUNC
1665,V,L,p.V1665L,Missense,-0.908947432730684,INT
1665,V,E,p.V1665E,Missense,-1.72003404972147,LOF
1665,V,A,p.V1665A,Missense,0.0120450653992291,FUNC
1665,V,G,p.V1665G,Missense,-0.535272180282592,FUNC
1665,V,V,p.V1665=,Synonymous,-0.756056507930088,INT
1665,V,V,p.V1665=,Synonymous,-0.0261778328267722,FUNC
1665,V,V,p.V1665=,Synonymous,-0.62659930574047,FUNC
1666,Y,N,p.Y1666N,Missense,0.0422381427035078,FUNC
1666,Y,H,p.Y1666H,Missense,0.733635001667553,FUNC
1666,Y,D,p.Y1666D,Missense,0.0285243314904038,FUNC
1666,Y,S,p.Y1666S,Missense,-0.151134008829013,FUNC
1666,Y,C,p.Y1666C,Missense,0.0834567638964395,FUNC
1666,Y,F,p.Y1666F,Missense,-0.0410385296899268,FUNC
1666,Y,*,p.Y1666*,Nonsense,-2.13890649104097,LOF
1666,Y,*,p.Y1666*,Nonsense,-2.07592550464515,LOF
1666,Y,Y,p.Y1666=,Synonymous,-0.913013371010718,INT
1667,K,Q,p.K1667Q,Missense,0.141199340310152,FUNC
1667,K,E,p.K1667E,Missense,0.270624841250294,FUNC
1667,K,*,p.K1667*,Nonsense,-1.74925525438724,LOF
1667,K,T,p.K1667T,Missense,-0.460669232265318,FUNC
1667,K,R,p.K1667R,Missense,-0.714818329248961,FUNC
1667,K,M,p.K1667M,Missense,0.132660390349475,FUNC
1667,K,K,p.K1667=,Synonymous,-0.334368910396347,FUNC
1667,K,N,p.K1667N,Missense,0.351816070530516,FUNC
1667,K,N,p.K1667N,Missense,-0.975486240720826,INT
1668,F,I,p.F1668I,Missense,-0.178816360415044,FUNC
1668,F,L,p.F1668L,Missense,0.25451072188575,FUNC
1668,F,V,p.F1668V,Missense,-0.663486748720714,FUNC
1668,F,Y,p.F1668Y,Missense,-0.0480501204869419,FUNC
1668,F,S,p.F1668S,Missense,-1.76068713282001,LOF
1668,F,C,p.F1668C,Missense,-0.325029891799594,FUNC
1668,F,L,p.F1668L,Missense,-1.48986275065846,LOF
1668,F,F,p.F1668=,Synonymous,0.0696946225163197,FUNC
1668,F,L,p.F1668L,Missense,-0.045968038805677,FUNC
1669,A,T,p.A1669T,Missense,0.0339712542980857,FUNC
1669,A,P,p.A1669P,Missense,-1.80328485545729,LOF
1669,A,S,p.A1669S,Missense,-0.401850536678059,FUNC
1669,A,D,p.A1669D,Missense,-1.01367646918871,INT
1669,A,G,p.A1669G,Missense,-0.336644052268107,FUNC
1669,A,A,p.A1669=,Synonymous,-0.236131454916941,FUNC
1669,A,A,p.A1669=,Synonymous,-0.33428932005291,FUNC
1669,A,A,p.A1669=,Synonymous,-1.03343510074123,INT
1670,R,R,p.R1670=,Synonymous,-0.163100651432117,FUNC
1670,R,G,p.R1670G,Missense,0.217765798580629,FUNC
1670,R,*,p.R1670*,Nonsense,-1.84515910573622,LOF
1670,R,K,p.R1670K,Missense,-1.5526979248423,LOF
1670,R,T,p.R1670T,Missense,-0.983168111206573,INT
1670,R,I,p.R1670I,Missense,-0.458163454357459,FUNC
1670,R,S,p.R1670S,Missense,-0.0803120886689186,FUNC
1670,R,R,p.R1670=,Synonymous,0.182761041607139,FUNC
1670,R,S,p.R1670S,Missense,-1.24504652154306,INT
1671,K,Q,p.K1671Q,Missense,0.242271090898514,FUNC
1671,K,E,p.K1671E,Missense,0.091841339263101,FUNC
1671,K,*,p.K1671*,Nonsense,-2.05313594274703,LOF
1671,K,T,p.K1671T,Missense,0.443511598385859,FUNC
1671,K,R,p.K1671R,Missense,0.298685820996946,FUNC
1671,K,I,p.K1671I,Missense,0.206516490834417,FUNC
1671,K,N,p.K1671N,Missense,0.244102201714296,FUNC
1671,K,K,p.K1671=,Synonymous,0.146243868067815,FUNC
1671,K,N,p.K1671N,Missense,0.0713959220967885,FUNC
1672,H,N,p.H1672N,Missense,0.0375932391571365,FUNC
1672,H,D,p.H1672D,Missense,-0.833162349825109,INT
1672,H,Y,p.H1672Y,Missense,-0.0834776237932384,FUNC
1672,H,P,p.H1672P,Missense,-1.60262225185189,LOF
1672,H,R,p.H1672R,Missense,0.504252734192833,FUNC
1672,H,L,p.H1672L,Missense,0.664878570566934,FUNC
1672,H,Q,p.H1672Q,Missense,-0.119693251978202,FUNC
1672,H,Q,p.H1672Q,Missense,0.0992263512184791,FUNC
1672,H,H,p.H1672=,Synonymous,-0.135022674388488,FUNC
1673,H,N,p.H1673N,Missense,-0.131497556925808,FUNC
1673,H,D,p.H1673D,Missense,-0.132855873387041,FUNC
1673,H,Y,p.H1673Y,Missense,0.205780715975802,FUNC
1673,H,P,p.H1673P,Missense,-0.0738043449361134,FUNC
1673,H,R,p.H1673R,Missense,0.0664151021583591,FUNC
1673,H,L,p.H1673L,Missense,0.660457445538879,FUNC
1673,H,Q,p.H1673Q,Missense,0.0105193311137168,FUNC
1673,H,Q,p.H1673Q,Missense,0.0388963155727365,FUNC
1673,H,H,p.H1673=,Synonymous,-0.199790682211903,FUNC
1674,I,L,p.I1674L,Missense,0.38405177714092,FUNC
1674,I,V,p.I1674V,Missense,0.262136307694458,FUNC
1674,I,T,p.I1674T,Missense,0.0283251714620372,FUNC
1675,T,P,p.T1675P,Missense,0.339670951153672,FUNC
1675,T,A,p.T1675A,Missense,0.227925244361821,FUNC
1675,T,S,p.T1675S,Missense,0.209150701803195,FUNC
1675,T,N,p.T1675N,Missense,0.0625141587768309,FUNC
1675,T,I,p.T1675I,Missense,0.036029592103107,FUNC
1676,L,I,p.L1676I,Missense,0.0583028527945309,FUNC
1676,L,L,p.L1676=,Synonymous,0.393340466533792,FUNC
1676,L,V,p.L1676V,Missense,0.207102010458948,FUNC
1676,L,*,p.L1676*,Nonsense,-2.20163952001858,LOF
1676,L,*,p.L1676*,Nonsense,-2.47766767778726,LOF
1676,L,F,p.L1676F,Missense,0.301227736741334,FUNC
1676,L,L,p.L1676=,Synonymous,0.257804390708302,FUNC
1676,L,F,p.L1676F,Missense,0.296732224724393,FUNC
1677,T,P,p.T1677P,Missense,-0.682736496686155,FUNC
1677,T,A,p.T1677A,Missense,-0.398041548203807,FUNC
1677,T,S,p.T1677S,Missense,0.303433411222314,FUNC
1677,T,N,p.T1677N,Missense,-0.203384270879142,FUNC
1677,T,S,p.T1677S,Missense,0.290125053311211,FUNC
1677,T,I,p.T1677I,Missense,-1.01369458943812,INT
1677,T,T,p.T1677=,Synonymous,0.49073531210526,FUNC
1677,T,T,p.T1677=,Synonymous,0.285450438428396,FUNC
1677,T,T,p.T1677=,Synonymous,0.158205002677354,FUNC
1678,N,H,p.N1678H,Missense,-0.163272826255675,FUNC
1678,N,D,p.N1678D,Missense,0.519645257077495,FUNC
1678,N,Y,p.N1678Y,Missense,-0.0799880288479798,FUNC
1678,N,T,p.N1678T,Missense,0.268235298294961,FUNC
1678,N,S,p.N1678S,Missense,0.202968896867008,FUNC
1678,N,I,p.N1678I,Missense,-0.693611146144146,FUNC
1678,N,K,p.N1678K,Missense,-0.171434971441411,FUNC
1678,N,N,p.N1678=,Synonymous,0.600870101034001,FUNC
1678,N,K,p.N1678K,Missense,0.193543714315205,FUNC
1679,L,I,p.L1679I,Missense,-0.0550390574224866,FUNC
1679,L,V,p.L1679V,Missense,0.370339922652456,FUNC
1679,L,L,p.L1679=,Synonymous,-0.152144221763348,FUNC
1679,L,Q,p.L1679Q,Missense,0.252101032040352,FUNC
1679,L,P,p.L1679P,Missense,0.117379358883917,FUNC
1679,L,R,p.L1679R,Missense,0.254610925722544,FUNC
1679,L,L,p.L1679=,Synonymous,0.0159453889728589,FUNC
1679,L,L,p.L1679=,Synonymous,0.488695714302194,FUNC
1679,L,L,p.L1679=,Synonymous,0.0757874720589704,FUNC
1680,I,L,p.I1680L,Missense,0.46138206695347,FUNC
1680,I,V,p.I1680V,Missense,0.158057630334892,FUNC
1680,I,F,p.I1680F,Missense,-0.100445937622947,FUNC
1680,I,N,p.I1680N,Missense,-0.243164420613263,FUNC
1680,I,T,p.I1680T,Missense,0.179818283382107,FUNC
1680,I,S,p.I1680S,Missense,-0.272118587848758,FUNC
1680,I,I,p.I1680=,Synonymous,0.272295231915403,FUNC
1680,I,I,p.I1680=,Synonymous,0.252286692093046,FUNC
1680,I,M,p.I1680M,Missense,0.0731228064368046,FUNC
1681,T,P,p.T1681P,Missense,-2.06614329700354,LOF
1681,T,A,p.T1681A,Missense,0.409708738780975,FUNC
1681,T,S,p.T1681S,Missense,0.273928924429128,FUNC
1681,T,N,p.T1681N,Missense,-0.463855564141791,FUNC
1681,T,S,p.T1681S,Missense,-0.671511512142404,FUNC
1681,T,I,p.T1681I,Missense,-0.786038537797987,INT
1681,T,T,p.T1681=,Synonymous,0.0959127865230063,FUNC
1681,T,T,p.T1681=,Synonymous,0.513758559599241,FUNC
1681,T,T,p.T1681=,Synonymous,0.288142122634005,FUNC
1682,E,K,p.E1682K,Missense,-1.79737657325658,LOF
1682,E,Q,p.E1682Q,Missense,-0.978868465162841,INT
1682,E,*,p.E1682*,Nonsense,-1.88492615185873,LOF
1682,E,A,p.E1682A,Missense,-0.449022249530502,FUNC
1682,E,G,p.E1682G,Missense,0.368825080885134,FUNC
1682,E,V,p.E1682V,Missense,-1.93963114321799,LOF
1682,E,D,p.E1682D,Missense,-0.454716175186164,FUNC
1682,E,E,p.E1682=,Synonymous,0.360497456300348,FUNC
1682,E,D,p.E1682D,Missense,-0.861915543183721,INT
1683,E,K,p.E1683K,Missense,-1.99075203431829,LOF
1683,E,Q,p.E1683Q,Missense,-2.02639001047962,LOF
1683,E,*,p.E1683*,Nonsense,-2.0605401439875,LOF
1683,E,A,p.E1683A,Missense,0.0372152595542146,FUNC
1683,E,G,p.E1683G,Missense,-1.09715052699131,INT
1683,E,V,p.E1683V,Missense,-1.33179339481114,LOF
1683,E,E,p.E1683=,Synonymous,-0.326100814225388,FUNC
1683,E,D,p.E1683D,Missense,-0.0264298477765078,FUNC
1683,E,D,p.E1683D,Missense,-0.162661633558131,FUNC
1684,T,P,p.T1684P,Missense,-1.46839239194786,LOF
1684,T,A,p.T1684A,Missense,-0.652545723760172,FUNC
1684,T,S,p.T1684S,Missense,0.132037925285364,FUNC
1684,T,N,p.T1684N,Missense,-1.25097378464764,INT
1684,T,S,p.T1684S,Missense,-1.30500871881027,INT
1684,T,I,p.T1684I,Missense,-1.97301469758871,LOF
1684,T,T,p.T1684=,Synonymous,0.0524136216960439,FUNC
1684,T,T,p.T1684=,Synonymous,0.404441827389662,FUNC
1684,T,T,p.T1684=,Synonymous,0.133023873838388,FUNC
1685,T,P,p.T1685P,Missense,-1.55788091808324,LOF
1685,T,A,p.T1685A,Missense,-1.84066821677464,LOF
1685,T,S,p.T1685S,Missense,0.290799794443049,FUNC
1685,T,N,p.T1685N,Missense,-1.82716868367959,LOF
1685,T,S,p.T1685S,Missense,-1.95088217697638,LOF
1685,T,I,p.T1685I,Missense,-1.99157621622867,LOF
1685,T,T,p.T1685=,Synonymous,0.029017660910223,FUNC
1685,T,T,p.T1685=,Synonymous,0.197275576974362,FUNC
1685,T,T,p.T1685=,Synonymous,0.0371852218402034,FUNC
1686,H,N,p.H1686N,Missense,-2.39408768163245,LOF
1686,H,D,p.H1686D,Missense,-1.65287524732297,LOF
1686,H,Y,p.H1686Y,Missense,-1.52725989883762,LOF
1686,H,P,p.H1686P,Missense,-1.96555669774893,LOF
1686,H,R,p.H1686R,Missense,-1.33663707255115,LOF
1686,H,L,p.H1686L,Missense,-1.55660726141289,LOF
1686,H,Q,p.H1686Q,Missense,-1.58542378596186,LOF
1686,H,H,p.H1686=,Synonymous,0.785939375903544,FUNC
1686,H,Q,p.H1686Q,Missense,-1.92896673964101,LOF
1687,V,I,p.V1687I,Missense,-0.264841012999907,FUNC
1687,V,L,p.V1687L,Missense,-0.0695057398421208,FUNC
1687,V,F,p.V1687F,Missense,-2.06998328574661,LOF
1687,V,D,p.V1687D,Missense,-1.81500055473855,LOF
1687,V,A,p.V1687A,Missense,-0.49127135676395,FUNC
1687,V,G,p.V1687G,Missense,-2.33428188148004,LOF
1687,V,V,p.V1687=,Synonymous,-0.544514158114669,FUNC
1687,V,V,p.V1687=,Synonymous,0.425717348306148,FUNC
1687,V,V,p.V1687=,Synonymous,-0.179469916447267,FUNC
1688,V,I,p.V1688I,Missense,0.0487756195300588,FUNC
1688,V,L,p.V1688L,Missense,-0.416440550810066,FUNC
1688,V,F,p.V1688F,Missense,-1.87389916872174,LOF
1688,V,D,p.V1688D,Missense,-1.572097204619,LOF
1688,V,A,p.V1688A,Missense,-0.322963559452218,FUNC
1688,V,G,p.V1688G,Missense,-2.29524923443772,LOF
1688,V,V,p.V1688=,Synonymous,-0.432747866651254,FUNC
1688,V,V,p.V1688=,Synonymous,0.200876185549824,FUNC
1688,V,V,p.V1688=,Synonymous,0.16567828543349,FUNC
1689,M,L,p.M1689L,Missense,-0.031839984390885,FUNC
1689,M,V,p.M1689V,Missense,0.561540403732137,FUNC
1689,M,L,p.M1689L,Missense,-0.484375978767089,FUNC
1689,M,K,p.M1689K,Missense,-1.81310947380306,LOF
1689,M,T,p.M1689T,Missense,0.0423165093843193,FUNC
1689,M,R,p.M1689R,Missense,-2.07742010103649,LOF
1689,M,I,p.M1689I,Missense,-0.187389885020822,FUNC
1689,M,I,p.M1689I,Missense,-0.095807980502264,FUNC
1689,M,I,p.M1689I,Missense,-0.531208814691158,FUNC
1690,K,Q,p.K1690Q,Missense,-0.11295632239409,FUNC
1690,K,E,p.K1690E,Missense,-0.629180784542703,FUNC
1690,K,*,p.K1690*,Nonsense,-2.0537387666319,LOF
1690,K,T,p.K1690T,Missense,-1.31957903213325,INT
1690,K,R,p.K1690R,Missense,0.130445950518252,FUNC
1690,K,I,p.K1690I,Missense,-1.15580221326794,INT
1690,K,N,p.K1690N,Missense,-0.0663439385520353,FUNC
1690,K,K,p.K1690=,Synonymous,0.123067756383239,FUNC
1690,K,N,p.K1690N,Missense,-0.186453522263936,FUNC
1691,T,P,p.T1691P,Missense,-1.73981718348605,LOF
1691,T,A,p.T1691A,Missense,-1.19623368401361,INT
1691,T,S,p.T1691S,Missense,0.0425238746825111,FUNC
1691,T,K,p.T1691K,Missense,-1.8549344846404,LOF
1691,T,R,p.T1691R,Missense,-2.04963143395105,LOF
1691,T,I,p.T1691I,Missense,-1.39646248988762,LOF
1691,T,T,p.T1691=,Splice region,-1.4266853208589,LOF
1691,T,T,p.T1691=,Splice region,-0.382578790416592,FUNC
1691,T,T,p.T1691=,Splice region,-1.48589434240788,LOF
1692,D,N,p.D1692N,Missense,-1.86484269773559,LOF
1692,D,H,p.D1692H,Missense,-1.57850831772585,LOF
1692,D,Y,p.D1692Y,Missense,-1.26893113631422,INT
1692,D,A,p.D1692A,Missense,-2.08088244719007,LOF
1692,D,G,p.D1692G,Missense,-1.11154238734675,INT
1692,D,V,p.D1692V,Missense,-1.68567250146284,LOF
1692,D,E,p.D1692E,Missense,-1.47827157191638,LOF
1692,D,D,p.D1692=,Splice region,0.0612013657834926,FUNC
1692,D,E,p.D1692E,Missense,-2.14733266205631,LOF
1693,A,T,p.A1693T,Missense,-0.44456790703932,FUNC
1693,A,P,p.A1693P,Missense,-0.192657401318603,FUNC
1693,A,S,p.A1693S,Missense,-1.47498609751051,LOF
1693,A,D,p.A1693D,Missense,-1.53999109836842,LOF
1693,A,G,p.A1693G,Missense,-1.02195909114583,INT
1693,A,V,p.A1693V,Missense,-1.67152473037458,LOF
1693,A,A,p.A1693=,Synonymous,-1.0146698689665,INT
1693,A,A,p.A1693=,Synonymous,0.103384146125433,FUNC
1693,A,A,p.A1693=,Synonymous,-0.0208571161895107,FUNC
1694,E,K,p.E1694K,Missense,-1.75545582628953,LOF
1694,E,Q,p.E1694Q,Missense,-0.604248156001507,FUNC
1694,E,*,p.E1694*,Nonsense,-2.09453761927996,LOF
1694,E,A,p.E1694A,Missense,0.14376162870311,FUNC
1694,E,G,p.E1694G,Missense,-0.0458899992366069,FUNC
1694,E,V,p.E1694V,Missense,-0.0264020467166021,FUNC
1694,E,E,p.E1694=,Synonymous,-0.0626352431792549,FUNC
1694,E,D,p.E1694D,Missense,0.10345692408347,FUNC
1694,E,D,p.E1694D,Missense,-0.187649735321438,FUNC
1695,F,I,p.F1695I,Missense,-1.02976164047738,INT
1695,F,L,p.F1695L,Missense,0.383736700711667,FUNC
1695,F,V,p.F1695V,Missense,-1.80194590499926,LOF
1695,F,Y,p.F1695Y,Missense,0.0190437075838132,FUNC
1695,F,S,p.F1695S,Missense,0.133192502693743,FUNC
1695,F,C,p.F1695C,Missense,-0.0224119193767083,FUNC
1695,F,L,p.F1695L,Missense,0.227802226615599,FUNC
1695,F,F,p.F1695=,Synonymous,0.00371595360311041,FUNC
1695,F,L,p.F1695L,Missense,-0.105779490505891,FUNC
1696,V,M,p.V1696M,Missense,-0.298896816341335,FUNC
1696,V,L,p.V1696L,Missense,-0.405383960609914,FUNC
1696,V,L,p.V1696L,Missense,-0.945259124798763,INT
1696,V,E,p.V1696E,Missense,-1.62238135182684,LOF
1696,V,A,p.V1696A,Missense,0.0368025416389476,FUNC
1696,V,G,p.V1696G,Missense,-1.32995644220045,LOF
1696,V,V,p.V1696=,Synonymous,-0.216494982809892,FUNC
1696,V,V,p.V1696=,Synonymous,0.020799816029216,FUNC
1696,V,V,p.V1696=,Synonymous,0.154762561373839,FUNC
1697,C,S,p.C1697S,Missense,-0.0692527583068329,FUNC
1697,C,R,p.C1697R,Missense,-2.14939219790443,LOF
1697,C,G,p.C1697G,Missense,-0.304249045914854,FUNC
1697,C,Y,p.C1697Y,Missense,-2.05778042605182,LOF
1697,C,S,p.C1697S,Missense,-0.0126952176159954,FUNC
1697,C,F,p.C1697F,Missense,-2.39625678181331,LOF
1697,C,*,p.C1697*,Nonsense,-2.0906585713085,LOF
1697,C,C,p.C1697=,Synonymous,-0.26155830530532,FUNC
1697,C,W,p.C1697W,Missense,-2.25007179772233,LOF
1698,E,K,p.E1698K,Missense,-0.0632612721528797,FUNC
1698,E,Q,p.E1698Q,Missense,-0.04377636640236,FUNC
1698,E,*,p.E1698*,Nonsense,-2.54587000858993,LOF
1698,E,A,p.E1698A,Missense,-0.0592878375597217,FUNC
1698,E,G,p.E1698G,Missense,-0.138484128581735,FUNC
1698,E,V,p.E1698V,Missense,-0.044283732168007,FUNC
1698,E,D,p.E1698D,Missense,0.0669790775432209,FUNC
1698,E,E,p.E1698=,Synonymous,-0.0454050611063513,FUNC
1698,E,D,p.E1698D,Missense,0.109190005791504,FUNC
1699,R,G,p.R1699G,Missense,-2.21016158778466,LOF
1699,R,P,p.R1699P,Missense,-1.54852253887007,LOF
1699,R,L,p.R1699L,Missense,-1.55594191209357,LOF
1700,T,P,p.T1700P,Missense,-2.27997885783161,LOF
1700,T,A,p.T1700A,Missense,-2.02289139685463,LOF
1700,T,K,p.T1700K,Missense,-2.07521732378461,LOF
1700,T,R,p.T1700R,Missense,-1.70494638656853,LOF
1700,T,I,p.T1700I,Missense,-2.4917463603023,LOF
1700,T,T,p.T1700=,Synonymous,0.0726188017602341,FUNC
1700,T,T,p.T1700=,Synonymous,0.338185218076868,FUNC
1700,T,T,p.T1700=,Synonymous,0.270923686751814,FUNC
1701,L,M,p.L1701M,Missense,0.183322291119681,FUNC
1701,L,V,p.L1701V,Missense,-0.118243585962721,FUNC
1701,L,L,p.L1701=,Synonymous,0.055994667343773,FUNC
1701,L,Q,p.L1701Q,Missense,-0.143577597349511,FUNC
1701,L,P,p.L1701P,Missense,-1.30043059133703,INT
1701,L,R,p.L1701R,Missense,-0.466710466384779,FUNC
1701,L,L,p.L1701=,Synonymous,-0.446391937715831,FUNC
1701,L,L,p.L1701=,Synonymous,-0.187546364394932,FUNC
1701,L,L,p.L1701=,Synonymous,-0.198903426212039,FUNC
1702,K,Q,p.K1702Q,Missense,-2.27878544497196,LOF
1702,K,E,p.K1702E,Missense,-2.02024969395035,LOF
1702,K,*,p.K1702*,Nonsense,-1.91932347026718,LOF
1702,K,T,p.K1702T,Missense,-1.58127112626744,LOF
1702,K,R,p.K1702R,Missense,-1.74109000592652,LOF
1702,K,I,p.K1702I,Missense,-2.017579190911,LOF
1702,K,N,p.K1702N,Missense,-1.97502726493262,LOF
1702,K,K,p.K1702=,Synonymous,0.4721945528791,FUNC
1702,K,N,p.K1702N,Missense,-1.94318975880589,LOF
1703,Y,N,p.Y1703N,Missense,-2.21296385091519,LOF
1703,Y,H,p.Y1703H,Missense,-1.70173509787402,LOF
1703,Y,D,p.Y1703D,Missense,-2.3485183496222,LOF
1703,Y,S,p.Y1703S,Missense,-2.06571989352332,LOF
1703,Y,C,p.Y1703C,Missense,-1.82025645390844,LOF
1703,Y,F,p.Y1703F,Missense,-0.18169642728139,FUNC
1703,Y,*,p.Y1703*,Nonsense,-2.30116145948069,LOF
1703,Y,Y,p.Y1703=,Synonymous,0.240886341937559,FUNC
1703,Y,*,p.Y1703*,Nonsense,-2.17137513987016,LOF
1704,F,I,p.F1704I,Missense,-1.4549475231569,LOF
1704,F,L,p.F1704L,Missense,-1.6652800811778,LOF
1704,F,V,p.F1704V,Missense,-2.14700798240513,LOF
1704,F,Y,p.F1704Y,Missense,-2.12341607412573,LOF
1704,F,S,p.F1704S,Missense,-2.11095371612758,LOF
1704,F,C,p.F1704C,Missense,-1.70622232990734,LOF
1704,F,L,p.F1704L,Missense,-1.78022072749526,LOF
1704,F,F,p.F1704=,Synonymous,0.194672920158382,FUNC
1704,F,L,p.F1704L,Missense,-1.85217401205403,LOF
1705,L,I,p.L1705I,Missense,-0.134881303377917,FUNC
1705,L,V,p.L1705V,Missense,-0.147693793089852,FUNC
1705,L,L,p.L1705=,Synonymous,-0.224553799429863,FUNC
1705,L,Q,p.L1705Q,Missense,-0.190565784256415,FUNC
1705,L,P,p.L1705P,Missense,-2.15431306069821,LOF
1705,L,R,p.L1705R,Missense,-1.17417485343466,INT
1705,L,L,p.L1705=,Synonymous,0.354333056849471,FUNC
1705,L,L,p.L1705=,Synonymous,0.114585457775908,FUNC
1705,L,L,p.L1705=,Synonymous,0.0816733854467378,FUNC
1706,G,R,p.G1706R,Missense,-2.37979763251402,LOF
1706,G,R,p.G1706R,Missense,-2.2386205548575,LOF
1706,G,*,p.G1706*,Nonsense,-1.91468665638428,LOF
1706,G,E,p.G1706E,Missense,-2.45298981846792,LOF
1706,G,A,p.G1706A,Missense,-0.0514299101353102,FUNC
1706,G,V,p.G1706V,Missense,-2.32297920678307,LOF
1706,G,G,p.G1706=,Synonymous,0.0122477727911042,FUNC
1706,G,G,p.G1706=,Synonymous,-0.216303527225695,FUNC
1706,G,G,p.G1706=,Synonymous,-0.0156629849893591,FUNC
1707,I,L,p.I1707L,Missense,0.0780221890285954,FUNC
1707,I,V,p.I1707V,Missense,0.0669096562221722,FUNC
1707,I,F,p.I1707F,Missense,-2.34821946101204,LOF
1707,I,N,p.I1707N,Missense,-0.68944467587699,FUNC
1707,I,T,p.I1707T,Missense,-0.143325094832241,FUNC
1707,I,S,p.I1707S,Missense,-2.29509445148828,LOF
1707,I,I,p.I1707=,Synonymous,0.125342755599968,FUNC
1707,I,I,p.I1707=,Synonymous,-0.0139300451562089,FUNC
1707,I,M,p.I1707M,Missense,-0.275064271198236,FUNC
1708,A,T,p.A1708T,Missense,-1.35945402070986,LOF
1708,A,P,p.A1708P,Missense,-2.26313074824134,LOF
1708,A,S,p.A1708S,Missense,-0.514801321531241,FUNC
1708,A,E,p.A1708E,Missense,-2.00825799679473,LOF
1708,A,G,p.A1708G,Missense,-2.2288835325415,LOF
1708,A,V,p.A1708V,Missense,-0.222956413017083,FUNC
1708,A,A,p.A1708=,Synonymous,0.0189387449236095,FUNC
1708,A,A,p.A1708=,Synonymous,-0.0248372063829283,FUNC
1708,A,A,p.A1708=,Synonymous,0.237607347057662,FUNC
1709,G,R,p.G1709R,Missense,-0.096214580373665,FUNC
1709,G,R,p.G1709R,Missense,-0.113058618989154,FUNC
1709,G,*,p.G1709*,Nonsense,-2.15429907048046,LOF
1709,G,E,p.G1709E,Missense,-0.558665497685808,FUNC
1709,G,A,p.G1709A,Missense,0.116068252212263,FUNC
1709,G,V,p.G1709V,Missense,-1.38260055577164,LOF
1709,G,G,p.G1709=,Synonymous,0.0646778485489811,FUNC
1709,G,G,p.G1709=,Synonymous,-1.65307191963688,LOF
1709,G,G,p.G1709=,Synonymous,-0.00261289704817614,FUNC
1710,G,R,p.G1710R,Missense,-0.0142971208608558,FUNC
1710,G,R,p.G1710R,Missense,0.383451487500113,FUNC
1710,G,*,p.G1710*,Nonsense,-2.09285018880736,LOF
1710,G,E,p.G1710E,Missense,-0.351688541962465,FUNC
1710,G,A,p.G1710A,Missense,-0.110930986057859,FUNC
1710,G,V,p.G1710V,Missense,-0.414221853203238,FUNC
1710,G,G,p.G1710=,Synonymous,0.0656514138729294,FUNC
1710,G,G,p.G1710=,Synonymous,-1.81666908741097,LOF
1710,G,G,p.G1710=,Synonymous,-0.360065518568396,FUNC
1711,K,Q,p.K1711Q,Missense,-0.00583109169688709,FUNC
1711,K,E,p.K1711E,Missense,-1.82511117125829,LOF
1711,K,*,p.K1711*,Nonsense,-2.19829513791326,LOF
1711,K,T,p.K1711T,Missense,-0.00869321278664709,FUNC
1711,K,R,p.K1711R,Missense,0.146135531160168,FUNC
1711,K,I,p.K1711I,Missense,-0.0841701800800844,FUNC
1711,K,N,p.K1711N,Missense,0.111147332019366,FUNC
1711,K,K,p.K1711=,Synonymous,0.0181773451482768,FUNC
1711,K,N,p.K1711N,Missense,-0.0411853526434731,FUNC
1712,W,R,p.W1712R,Missense,-0.294256432409263,FUNC
1712,W,R,p.W1712R,Missense,-0.237008767323878,FUNC
1712,W,G,p.W1712G,Missense,-2.13625021853579,LOF
1712,W,*,p.W1712*,Nonsense,-2.12568785885006,LOF
1712,W,S,p.W1712S,Missense,-0.354519980146919,FUNC
1712,W,L,p.W1712L,Missense,-0.333901530860233,FUNC
1712,W,*,p.W1712*,Nonsense,-2.11859545077109,LOF
1712,W,C,p.W1712C,Missense,0.0832869832538611,FUNC
1712,W,C,p.W1712C,Missense,-0.000406721118817999,FUNC
1713,V,I,p.V1713I,Missense,0.228950410691537,FUNC
1713,V,L,p.V1713L,Missense,0.210837511772931,FUNC
1713,V,L,p.V1713L,Missense,-1.92326659071942,LOF
1713,V,E,p.V1713E,Missense,-2.18378786479938,LOF
1713,V,A,p.V1713A,Missense,-1.75547648459117,LOF
1713,V,G,p.V1713G,Missense,-1.8879503100562,LOF
1713,V,V,p.V1713=,Synonymous,0.146158245695191,FUNC
1713,V,V,p.V1713=,Synonymous,-0.0457352206195591,FUNC
1713,V,V,p.V1713=,Synonymous,-0.340548122142082,FUNC
1714,V,I,p.V1714I,Missense,-0.438877129298103,FUNC
1714,V,L,p.V1714L,Missense,-0.0114337714354798,FUNC
1714,V,F,p.V1714F,Missense,-1.85475531472936,LOF
1714,V,D,p.V1714D,Missense,-2.07499506323185,LOF
1714,V,A,p.V1714A,Missense,-1.29933885250151,INT
1714,V,G,p.V1714G,Missense,-2.07940917756532,LOF
1714,V,V,p.V1714=,Synonymous,0.109106471653949,FUNC
1714,V,V,p.V1714=,Synonymous,0.166133664524083,FUNC
1714,V,V,p.V1714=,Synonymous,0.307518525041627,FUNC
1715,S,R,p.S1715R,Missense,-2.20976678188052,LOF
1715,S,G,p.S1715G,Missense,-0.894501574753586,INT
1715,S,C,p.S1715C,Missense,-1.69865942698826,LOF
1715,S,N,p.S1715N,Missense,-2.29465730718365,LOF
1715,S,T,p.S1715T,Missense,-0.543038027941527,FUNC
1715,S,I,p.S1715I,Missense,-2.02304073420135,LOF
1715,S,R,p.S1715R,Missense,-1.7697072764081,LOF
1715,S,R,p.S1715R,Missense,-1.8710630832529,LOF
1715,S,S,p.S1715=,Synonymous,-0.450533085684926,FUNC
1716,Y,N,p.Y1716N,Missense,0.0180862415763089,FUNC
1716,Y,H,p.Y1716H,Missense,0.293174677694855,FUNC
1716,Y,D,p.Y1716D,Missense,0.0179895420377151,FUNC
1716,Y,S,p.Y1716S,Missense,0.0689576451028077,FUNC
1716,Y,C,p.Y1716C,Missense,-0.344807991501031,FUNC
1716,Y,F,p.Y1716F,Missense,0.0618708800715862,FUNC
1716,Y,*,p.Y1716*,Nonsense,-1.85893283273228,LOF
1716,Y,Y,p.Y1716=,Synonymous,-0.0806873755780593,FUNC
1716,Y,*,p.Y1716*,Nonsense,-2.12276285838404,LOF
1717,F,I,p.F1717I,Missense,-0.567159028121673,FUNC
1717,F,L,p.F1717L,Missense,-0.307746997998791,FUNC
1717,F,V,p.F1717V,Missense,0.00930493667091151,FUNC
1717,F,Y,p.F1717Y,Missense,0.0210420585919195,FUNC
1717,F,S,p.F1717S,Missense,0.0386522941845642,FUNC
1717,F,C,p.F1717C,Missense,0.169709433237894,FUNC
1717,F,L,p.F1717L,Missense,0.308719888990305,FUNC
1717,F,L,p.F1717L,Missense,0.198285169745619,FUNC
1717,F,F,p.F1717=,Splice region,-0.418476991336772,FUNC
1718,W,R,p.W1718R,Missense,-1.67812259248343,LOF
1718,W,R,p.W1718R,Missense,-1.65033223593827,LOF
1718,W,G,p.W1718G,Missense,-1.8749475988444,LOF
1718,W,*,p.W1718*,Nonsense,-2.0410258566992,LOF
1718,W,S,p.W1718S,Missense,-1.18670294493015,INT
1718,W,L,p.W1718L,Missense,-1.37115523247543,LOF
1718,W,*,p.W1718*,Nonsense,-1.52891019136961,LOF
1718,W,C,p.W1718C,Missense,-1.44391884462746,LOF
1718,W,C,p.W1718C,Missense,-1.57570770533006,LOF
1719,V,M,p.V1719M,Missense,-0.540558899922355,FUNC
1719,V,L,p.V1719L,Missense,-0.154702436226783,FUNC
1719,V,L,p.V1719L,Missense,-0.561705912887115,FUNC
1719,V,E,p.V1719E,Missense,-1.925277452256,LOF
1719,V,A,p.V1719A,Missense,0.374786795778128,FUNC
1719,V,G,p.V1719G,Missense,-1.38364631033649,LOF
1719,V,V,p.V1719=,Synonymous,-0.0180489131135941,FUNC
1719,V,V,p.V1719=,Synonymous,0.400139371031409,FUNC
1719,V,V,p.V1719=,Synonymous,0.0961133162857967,FUNC
1720,T,A,p.T1720A,Missense,0.132285866292813,FUNC
1720,T,S,p.T1720S,Missense,0.380406588986614,FUNC
1721,Q,K,p.Q1721K,Missense,-0.00847707944480156,FUNC
1721,Q,E,p.Q1721E,Missense,-0.120205616662937,FUNC
1721,Q,*,p.Q1721*,Nonsense,-2.03260136546654,LOF
1721,Q,P,p.Q1721P,Missense,-2.3527407820664,LOF
1721,Q,R,p.Q1721R,Missense,-0.203878344046421,FUNC
1721,Q,L,p.Q1721L,Missense,0.0558479617041704,FUNC
1721,Q,Q,p.Q1721=,Synonymous,0.283238014279448,FUNC
1721,Q,H,p.Q1721H,Missense,0.0546793976067769,FUNC
1721,Q,H,p.Q1721H,Missense,0.0895269484212073,FUNC
1722,S,T,p.S1722T,Missense,-0.377101066738486,FUNC
1722,S,P,p.S1722P,Missense,-1.65174166954429,LOF
1722,S,A,p.S1722A,Missense,0.0294942540157065,FUNC
1722,S,Y,p.S1722Y,Missense,-1.284016223324,INT
1722,S,C,p.S1722C,Missense,0.197527537137091,FUNC
1722,S,F,p.S1722F,Missense,-0.834246378904467,INT
1722,S,S,p.S1722=,Synonymous,0.27822346101053,FUNC
1722,S,S,p.S1722=,Synonymous,-0.192959677187021,FUNC
1722,S,S,p.S1722=,Synonymous,-0.494208063219312,FUNC
1723,I,L,p.I1723L,Missense,0.054043045896751,FUNC
1723,I,V,p.I1723V,Missense,0.283315190650487,FUNC
1723,I,F,p.I1723F,Missense,0.215808298849231,FUNC
1723,I,N,p.I1723N,Missense,-0.126123104878339,FUNC
1723,I,T,p.I1723T,Missense,0.355145638120542,FUNC
1723,I,S,p.I1723S,Missense,-0.267795186773311,FUNC
1723,I,I,p.I1723=,Synonymous,-0.358117557455242,FUNC
1723,I,I,p.I1723=,Synonymous,0.253956551746971,FUNC
1723,I,M,p.I1723M,Missense,0.0077999202692951,FUNC
1724,K,Q,p.K1724Q,Missense,-0.342907544648298,FUNC
1724,K,E,p.K1724E,Missense,-0.0512711570716132,FUNC
1724,K,*,p.K1724*,Nonsense,-2.02204393036993,LOF
1724,K,T,p.K1724T,Missense,-0.193830017977299,FUNC
1724,K,R,p.K1724R,Missense,-0.000931561535200605,FUNC
1724,K,I,p.K1724I,Missense,-0.188903344356375,FUNC
1724,K,N,p.K1724N,Missense,-0.0579574557127119,FUNC
1724,K,K,p.K1724=,Synonymous,0.0520143146291834,FUNC
1724,K,N,p.K1724N,Missense,-0.308207564527426,FUNC
1725,E,K,p.E1725K,Missense,-0.46171689736591,FUNC
1725,E,Q,p.E1725Q,Missense,-0.411198293924892,FUNC
1725,E,*,p.E1725*,Nonsense,-2.3508691938645,LOF
1725,E,A,p.E1725A,Missense,0.185373964408539,FUNC
1725,E,G,p.E1725G,Missense,0.230840789668226,FUNC
1725,E,V,p.E1725V,Missense,-0.276712989290451,FUNC
1725,E,D,p.E1725D,Missense,0.0777980002138893,FUNC
1725,E,E,p.E1725=,Synonymous,0.248392834919932,FUNC
1725,E,D,p.E1725D,Missense,-0.155152045940699,FUNC
1726,R,R,p.R1726=,Synonymous,0.475157505710567,FUNC
1726,R,G,p.R1726G,Missense,0.139873672712294,FUNC
1726,R,*,p.R1726*,Nonsense,-2.00445095776967,LOF
1726,R,K,p.R1726K,Missense,0.0656067842873872,FUNC
1726,R,T,p.R1726T,Missense,-0.108020882242448,FUNC
1726,R,I,p.R1726I,Missense,-0.313708723061628,FUNC
1726,R,S,p.R1726S,Missense,-0.145743967764718,FUNC
1726,R,R,p.R1726=,Synonymous,0.0308070380685877,FUNC
1726,R,S,p.R1726S,Missense,-0.143931107250253,FUNC
1727,K,Q,p.K1727Q,Missense,0.295675239099518,FUNC
1727,K,E,p.K1727E,Missense,0.552034290481192,FUNC
1727,K,*,p.K1727*,Nonsense,-2.05135817653836,LOF
1727,K,T,p.K1727T,Missense,0.177259857532857,FUNC
1727,K,R,p.K1727R,Missense,0.0900038341499813,FUNC
1727,K,I,p.K1727I,Missense,0.0220535197656234,FUNC
1727,K,N,p.K1727N,Missense,0.0689402871835359,FUNC
1727,K,K,p.K1727=,Synonymous,0.214590703361762,FUNC
1727,K,N,p.K1727N,Missense,0.125853778071299,FUNC
1728,M,L,p.M1728L,Missense,0.222922540190683,FUNC
1728,M,V,p.M1728V,Missense,0.113929224486424,FUNC
1728,M,L,p.M1728L,Missense,-0.292013268726379,FUNC
1728,M,K,p.M1728K,Missense,0.243499452893055,FUNC
1728,M,T,p.M1728T,Missense,0.164069414719365,FUNC
1728,M,R,p.M1728R,Missense,-0.298201446477928,FUNC
1728,M,I,p.M1728I,Missense,-0.296985542916493,FUNC
1728,M,I,p.M1728I,Missense,0.151964853340206,FUNC
1728,M,I,p.M1728I,Missense,-0.330405631968417,FUNC
1729,L,M,p.L1729M,Missense,-0.437496984672759,FUNC
1729,L,V,p.L1729V,Missense,0.196300676287272,FUNC
1729,L,L,p.L1729=,Synonymous,0.383489098082072,FUNC
1729,L,Q,p.L1729Q,Missense,-0.129532584438802,FUNC
1729,L,P,p.L1729P,Missense,-1.25811813513376,INT
1729,L,R,p.L1729R,Missense,0.0703330776660542,FUNC
1729,L,L,p.L1729=,Synonymous,0.144988334328104,FUNC
1729,L,L,p.L1729=,Synonymous,-0.367738769741174,FUNC
1729,L,L,p.L1729=,Synonymous,-0.04888860011054,FUNC
1730,N,H,p.N1730H,Missense,0.421659853859503,FUNC
1730,N,D,p.N1730D,Missense,-0.00364215944083648,FUNC
1730,N,Y,p.N1730Y,Missense,0.424933599982885,FUNC
1730,N,T,p.N1730T,Missense,-0.178811215209827,FUNC
1730,N,S,p.N1730S,Missense,0.2324219120117,FUNC
1730,N,I,p.N1730I,Missense,-0.329646109752361,FUNC
1730,N,K,p.N1730K,Missense,0.3480501399721,FUNC
1730,N,N,p.N1730=,Synonymous,-0.0771402200058652,FUNC
1730,N,K,p.N1730K,Missense,0.0209487335187599,FUNC
1731,E,K,p.E1731K,Missense,-2.76977608894852,LOF
1731,E,Q,p.E1731Q,Missense,-0.858680579594784,INT
1731,E,*,p.E1731*,Nonsense,-2.26234030610252,LOF
1731,E,A,p.E1731A,Missense,0.275906423444003,FUNC
1731,E,G,p.E1731G,Missense,0.0652273024678645,FUNC
1731,E,V,p.E1731V,Missense,-0.203848214856568,FUNC
1731,E,E,p.E1731=,Splice region,-0.377828008416012,FUNC
1731,E,D,p.E1731D,Missense,0.125432781176861,FUNC
1731,E,D,p.E1731D,Missense,-0.0311382534387421,FUNC
1732,H,N,p.H1732N,Missense,-0.586664005450233,FUNC
1732,H,D,p.H1732D,Missense,-0.176629406133256,FUNC
1732,H,Y,p.H1732Y,Missense,-0.662483092285522,FUNC
1732,H,P,p.H1732P,Missense,0.145482325874027,FUNC
1732,H,R,p.H1732R,Missense,0.333391435759715,FUNC
1732,H,L,p.H1732L,Missense,0.0711204235626537,FUNC
1732,H,Q,p.H1732Q,Missense,-0.10668093964534,FUNC
1732,H,H,p.H1732=,Splice region,-0.428338464401921,FUNC
1732,H,Q,p.H1732Q,Missense,-0.0218130602742898,FUNC
1733,D,N,p.D1733N,Missense,-0.511247529135134,FUNC
1733,D,H,p.D1733H,Missense,-0.0544888779988724,FUNC
1733,D,Y,p.D1733Y,Missense,-0.633444213473719,FUNC
1733,D,A,p.D1733A,Missense,0.15892725556448,FUNC
1733,D,G,p.D1733G,Missense,0.167600773623651,FUNC
1733,D,V,p.D1733V,Missense,-0.44524404896313,FUNC
1733,D,E,p.D1733E,Missense,0.225810609562834,FUNC
1733,D,D,p.D1733=,Synonymous,0.539590361496505,FUNC
1733,D,E,p.D1733E,Missense,-0.15105965558932,FUNC
1734,F,I,p.F1734I,Missense,-2.255002356117,LOF
1734,F,L,p.F1734L,Missense,-2.37335995851566,LOF
1734,F,V,p.F1734V,Missense,-2.48102119631926,LOF
1734,F,Y,p.F1734Y,Missense,-0.123011325987207,FUNC
1734,F,S,p.F1734S,Missense,-2.03380972937082,LOF
1734,F,C,p.F1734C,Missense,-3.36637907971901,LOF
1734,F,L,p.F1734L,Missense,-2.07764056089949,LOF
1734,F,F,p.F1734=,Synonymous,0.267652906918833,FUNC
1734,F,L,p.F1734L,Missense,-1.86829986271098,LOF
1735,E,K,p.E1735K,Missense,-3.24294554301487,LOF
1735,E,Q,p.E1735Q,Missense,-0.249794861930793,FUNC
1735,E,*,p.E1735*,Nonsense,-2.51366940032183,LOF
1735,E,A,p.E1735A,Missense,-0.503115481571585,FUNC
1735,E,G,p.E1735G,Missense,-1.83511967503451,LOF
1735,E,V,p.E1735V,Missense,0.098740886622499,FUNC
1735,E,D,p.E1735D,Missense,-1.23085086200007,INT
1735,E,E,p.E1735=,Synonymous,0.155928951822803,FUNC
1735,E,D,p.E1735D,Missense,-1.3708641746553,LOF
1736,V,I,p.V1736I,Missense,-0.0519344224261735,FUNC
1736,V,L,p.V1736L,Missense,-1.8453446674036,LOF
1736,V,F,p.V1736F,Missense,-2.38046370206342,LOF
1736,V,D,p.V1736D,Missense,-1.93117329228485,LOF
1736,V,A,p.V1736A,Missense,-1.60309259931805,LOF
1736,V,G,p.V1736G,Missense,-1.73329333871728,LOF
1736,V,V,p.V1736=,Synonymous,-0.506501923969361,FUNC
1736,V,V,p.V1736=,Synonymous,-0.450156396006957,FUNC
1736,V,V,p.V1736=,Synonymous,-0.343492511775943,FUNC
1737,R,R,p.R1737=,Synonymous,-0.308566407916435,FUNC
1737,R,G,p.R1737G,Missense,-0.347344956460014,FUNC
1737,R,*,p.R1737*,Nonsense,-1.99741819563986,LOF
1737,R,K,p.R1737K,Missense,-0.949347402930345,INT
1737,R,T,p.R1737T,Missense,-0.0295141559555856,FUNC
1737,R,I,p.R1737I,Missense,0.204096135852601,FUNC
1737,R,S,p.R1737S,Missense,0.100274640908955,FUNC
1737,R,R,p.R1737=,Synonymous,0.0179952049464008,FUNC
1737,R,S,p.R1737S,Missense,-0.117326913162943,FUNC
1738,G,R,p.G1738R,Missense,-3.66162045301671,LOF
1738,G,R,p.G1738R,Missense,-1.7979744662235,LOF
1738,G,*,p.G1738*,Nonsense,-2.91252448692479,LOF
1738,G,E,p.G1738E,Missense,-2.6353416209094,LOF
1738,G,A,p.G1738A,Missense,-2.42390360666334,LOF
1738,G,V,p.G1738V,Missense,-2.73932554710575,LOF
1738,G,G,p.G1738=,Synonymous,0.124340892959236,FUNC
1738,G,G,p.G1738=,Synonymous,-0.142443664551307,FUNC
1738,G,G,p.G1738=,Synonymous,-0.0987662052409328,FUNC
1739,D,N,p.D1739N,Missense,-0.114011823555723,FUNC
1739,D,H,p.D1739H,Missense,-2.76713407948034,LOF
1739,D,Y,p.D1739Y,Missense,-2.52911977546105,LOF
1739,D,A,p.D1739A,Missense,-2.47564640183266,LOF
1739,D,G,p.D1739G,Missense,-2.43103072960453,LOF
1739,D,V,p.D1739V,Missense,-1.99376742157678,LOF
1739,D,E,p.D1739E,Missense,-2.66051709021516,LOF
1739,D,D,p.D1739=,Synonymous,0.218052906198297,FUNC
1739,D,E,p.D1739E,Missense,-2.9131674176071,LOF
1740,V,L,p.V1740L,Missense,-0.0635160678177613,FUNC
1740,V,A,p.V1740A,Missense,0.0796598527324661,FUNC
1740,V,G,p.V1740G,Missense,-0.506044073452074,FUNC
1741,V,I,p.V1741I,Missense,0.162782347112225,FUNC
1741,V,L,p.V1741L,Missense,-0.782954662707449,INT
1741,V,D,p.V1741D,Missense,-1.90564466017491,LOF
1741,V,A,p.V1741A,Missense,-0.274187750020751,FUNC
1741,V,V,p.V1741=,Synonymous,-0.00824256072992503,FUNC
1741,V,V,p.V1741=,Synonymous,-0.489737565008687,FUNC
1741,V,V,p.V1741=,Synonymous,0.328549779311773,FUNC
1742,N,H,p.N1742H,Missense,-0.0283156120907143,FUNC
1742,N,D,p.N1742D,Missense,-0.749588491501205,INT
1742,N,Y,p.N1742Y,Missense,-1.12392730196856,INT
1742,N,T,p.N1742T,Missense,0.20615039022212,FUNC
1742,N,S,p.N1742S,Missense,0.0672293407127807,FUNC
1742,N,I,p.N1742I,Missense,-0.341116350680095,FUNC
1742,N,K,p.N1742K,Missense,-0.12282118756865,FUNC
1742,N,N,p.N1742=,Synonymous,-0.0704793491435253,FUNC
1742,N,K,p.N1742K,Missense,0.540731210389182,FUNC
1743,G,R,p.G1743R,Missense,-2.68142149701781,LOF
1743,G,R,p.G1743R,Missense,-1.92408140420611,LOF
1743,G,*,p.G1743*,Nonsense,-2.2414023845974,LOF
1743,G,E,p.G1743E,Missense,-2.83110591414681,LOF
1743,G,A,p.G1743A,Missense,-1.2133956437475,INT
1743,G,V,p.G1743V,Missense,-1.68946229831907,LOF
1743,G,G,p.G1743=,Synonymous,0.360324822457256,FUNC
1743,G,G,p.G1743=,Synonymous,-0.0707181656582726,FUNC
1743,G,G,p.G1743=,Synonymous,0.0649019798891134,FUNC
1744,R,R,p.R1744=,Synonymous,0.329757712967313,FUNC
1744,R,G,p.R1744G,Missense,-0.0269147982418661,FUNC
1744,R,*,p.R1744*,Nonsense,-2.1145772926934,LOF
1744,R,K,p.R1744K,Missense,0.21732441862255,FUNC
1744,R,T,p.R1744T,Missense,-0.355909944798179,FUNC
1744,R,I,p.R1744I,Missense,-0.611578163304056,FUNC
1744,R,S,p.R1744S,Missense,0.260545899950064,FUNC
1744,R,R,p.R1744=,Synonymous,0.38995665122492,FUNC
1744,R,S,p.R1744S,Missense,-0.11636936979822,FUNC
1745,N,H,p.N1745H,Missense,0.209290415162896,FUNC
1745,N,D,p.N1745D,Missense,0.0798876815306015,FUNC
1745,N,Y,p.N1745Y,Missense,0.0652348131505834,FUNC
1745,N,T,p.N1745T,Missense,-0.0732784349387799,FUNC
1745,N,S,p.N1745S,Missense,0.195848238107692,FUNC
1745,N,I,p.N1745I,Missense,0.519271991337878,FUNC
1745,N,K,p.N1745K,Missense,-0.20810878284008,FUNC
1745,N,K,p.N1745K,Missense,-0.0515057974345672,FUNC
1745,N,N,p.N1745=,Synonymous,0.0625189239061423,FUNC
1746,H,N,p.H1746N,Missense,-0.759565561641431,INT
1746,H,D,p.H1746D,Missense,-1.77916801513549,LOF
1746,H,Y,p.H1746Y,Missense,-2.30474570198782,LOF
1746,H,P,p.H1746P,Missense,-2.56647745711579,LOF
1746,H,R,p.H1746R,Missense,-0.566534226741842,FUNC
1746,H,L,p.H1746L,Missense,-0.470063509014949,FUNC
1746,H,Q,p.H1746Q,Missense,-1.29795396252167,INT
1746,H,Q,p.H1746Q,Missense,-0.896827549620317,INT
1746,H,H,p.H1746=,Synonymous,0.164617721077255,FUNC
1747,Q,K,p.Q1747K,Missense,-0.417318658204963,FUNC
1747,Q,E,p.Q1747E,Missense,-0.371298204698049,FUNC
1747,Q,*,p.Q1747*,Nonsense,-1.98857000490843,LOF
1747,Q,P,p.Q1747P,Missense,-2.10520842888013,LOF
1747,Q,R,p.Q1747R,Missense,0.200842360256771,FUNC
1747,Q,L,p.Q1747L,Missense,0.161184595349292,FUNC
1747,Q,H,p.Q1747H,Missense,0.259271394211438,FUNC
1747,Q,Q,p.Q1747=,Synonymous,0.391096104713464,FUNC
1747,Q,H,p.Q1747H,Missense,0.00233877706417292,FUNC
1748,G,S,p.G1748S,Missense,-0.375461918556085,FUNC
1748,G,R,p.G1748R,Missense,-3.093498513306,LOF
1748,G,C,p.G1748C,Missense,-2.70685116425705,LOF
1748,G,D,p.G1748D,Missense,-1.65189918694954,LOF
1748,G,A,p.G1748A,Missense,-0.721756324843375,FUNC
1748,G,V,p.G1748V,Missense,-1.26800840696668,INT
1748,G,G,p.G1748=,Synonymous,0.153824310882202,FUNC
1748,G,G,p.G1748=,Synonymous,0.200116191489758,FUNC
1748,G,G,p.G1748=,Synonymous,0.316666172017439,FUNC
1749,P,T,p.P1749T,Missense,-0.653988637489678,FUNC
1749,P,A,p.P1749A,Missense,-0.153996474848308,FUNC
1749,P,S,p.P1749S,Missense,-1.44884666973584,LOF
1749,P,Q,p.P1749Q,Missense,-2.67598713648037,LOF
1749,P,R,p.P1749R,Missense,-3.30606251329229,LOF
1749,P,L,p.P1749L,Missense,-2.09151893906852,LOF
1749,P,P,p.P1749=,Synonymous,0.219430847040001,FUNC
1749,P,P,p.P1749=,Synonymous,0.41214121743091,FUNC
1749,P,P,p.P1749=,Synonymous,-0.249093612541497,FUNC
1750,K,Q,p.K1750Q,Missense,0.290074466178338,FUNC
1750,K,E,p.K1750E,Missense,-0.630633801527626,FUNC
1750,K,*,p.K1750*,Nonsense,-2.3666138023182,LOF
1750,K,T,p.K1750T,Missense,-0.166920920342634,FUNC
1750,K,R,p.K1750R,Missense,0.36494441925085,FUNC
1750,K,M,p.K1750M,Missense,-0.0415723696356363,FUNC
1750,K,K,p.K1750=,Synonymous,-0.195854771501375,FUNC
1750,K,N,p.K1750N,Missense,-0.892868065547171,INT
1750,K,N,p.K1750N,Missense,-0.185011354531884,FUNC
1751,R,R,p.R1751=,Synonymous,-0.355861922518864,FUNC
1751,R,G,p.R1751G,Missense,-1.47251566605134,LOF
1751,R,*,p.R1751*,Nonsense,-1.87649998421636,LOF
1751,R,Q,p.R1751Q,Missense,-0.149920264367993,FUNC
1751,R,P,p.R1751P,Missense,-2.86078706822763,LOF
1751,R,L,p.R1751L,Missense,-0.371918700338791,FUNC
1751,R,R,p.R1751=,Synonymous,0.40129868655116,FUNC
1751,R,R,p.R1751=,Synonymous,0.489955248387452,FUNC
1751,R,R,p.R1751=,Synonymous,-0.0498329670906553,FUNC
1752,A,T,p.A1752T,Missense,-2.58578875937239,LOF
1752,A,P,p.A1752P,Missense,-3.12678112656794,LOF
1752,A,S,p.A1752S,Missense,0.0189622694832067,FUNC
1752,A,E,p.A1752E,Missense,-3.03783022295038,LOF
1752,A,G,p.A1752G,Missense,-0.281368161514999,FUNC
1752,A,V,p.A1752V,Missense,-1.73849196243126,LOF
1752,A,A,p.A1752=,Synonymous,0.0912334524479238,FUNC
1752,A,A,p.A1752=,Synonymous,0.0097993804289441,FUNC
1752,A,A,p.A1752=,Synonymous,-0.180594389147702,FUNC
1753,R,R,p.R1753=,Synonymous,0.0698138946969838,FUNC
1753,R,G,p.R1753G,Missense,-2.42141511261047,LOF
1753,R,*,p.R1753*,Nonsense,-2.06271179312895,LOF
1753,R,K,p.R1753K,Missense,-1.93432470177664,LOF
1753,R,T,p.R1753T,Missense,-2.37042043719014,LOF
1753,R,I,p.R1753I,Missense,-2.51698197764131,LOF
1753,R,S,p.R1753S,Missense,-2.93180106006303,LOF
1753,R,R,p.R1753=,Synonymous,-0.017985689984031,FUNC
1753,R,S,p.R1753S,Missense,-2.12871558698918,LOF
1754,E,K,p.E1754K,Missense,-0.318323795563548,FUNC
1754,E,Q,p.E1754Q,Missense,0.015345887486118,FUNC
1754,E,*,p.E1754*,Nonsense,-3.14051876345443,LOF
1754,E,A,p.E1754A,Missense,0.283962925901247,FUNC
1754,E,G,p.E1754G,Missense,-0.106235488064118,FUNC
1754,E,V,p.E1754V,Missense,-0.0576903468593412,FUNC
1754,E,D,p.E1754D,Missense,-0.126836886321088,FUNC
1754,E,E,p.E1754=,Synonymous,0.296128260203113,FUNC
1754,E,D,p.E1754D,Missense,0.0574245586962219,FUNC
1755,S,T,p.S1755T,Missense,-0.188463323960415,FUNC
1755,S,P,p.S1755P,Missense,-0.282334303748467,FUNC
1755,S,A,p.S1755A,Missense,-0.183185182149014,FUNC
1755,S,Y,p.S1755Y,Missense,-0.484283481118786,FUNC
1755,S,C,p.S1755C,Missense,0.121448366446748,FUNC
1755,S,F,p.S1755F,Missense,-0.154077949192117,FUNC
1755,S,S,p.S1755=,Synonymous,-0.351463123745536,FUNC
1755,S,S,p.S1755=,Synonymous,0.339693320752691,FUNC
1755,S,S,p.S1755=,Synonymous,-0.105173305285292,FUNC
1756,Q,K,p.Q1756K,Missense,-0.285468104106092,FUNC
1756,Q,E,p.Q1756E,Missense,0.587609003785149,FUNC
1756,Q,*,p.Q1756*,Nonsense,-1.82602819902656,LOF
1756,Q,P,p.Q1756P,Missense,0.1197686902868,FUNC
1756,Q,R,p.Q1756R,Missense,0.260614439571262,FUNC
1756,Q,L,p.Q1756L,Missense,0.418980605991002,FUNC
1756,Q,Q,p.Q1756=,Synonymous,-0.159504619773145,FUNC
1756,Q,H,p.Q1756H,Missense,-0.287596633595474,FUNC
1756,Q,H,p.Q1756H,Missense,-0.190212843375654,FUNC
1757,D,N,p.D1757N,Missense,-0.146850127888132,FUNC
1757,D,H,p.D1757H,Missense,0.00361173584827042,FUNC
1757,D,Y,p.D1757Y,Missense,0.0919519098307808,FUNC
1757,D,A,p.D1757A,Missense,0.337990578825393,FUNC
1757,D,G,p.D1757G,Missense,-0.229136319951464,FUNC
1757,D,V,p.D1757V,Missense,-0.0650950637280464,FUNC
1757,D,E,p.D1757E,Missense,-0.0407180388420184,FUNC
1757,D,E,p.D1757E,Missense,0.0419794484315714,FUNC
1757,D,D,p.D1757=,Synonymous,-0.2639246452523,FUNC
1758,R,R,p.R1758=,Synonymous,0.410264170655137,FUNC
1758,R,G,p.R1758G,Missense,0.315491623703113,FUNC
1758,R,*,p.R1758*,Nonsense,-2.06556899007562,LOF
1758,R,K,p.R1758K,Missense,0.0590759468708939,FUNC
1758,R,T,p.R1758T,Missense,-0.107145801468906,FUNC
1758,R,I,p.R1758I,Missense,-0.170083405201427,FUNC
1758,R,S,p.R1758S,Missense,-0.182165926529833,FUNC
1758,R,R,p.R1758=,Synonymous,0.513196539394858,FUNC
1758,R,S,p.R1758S,Missense,0.103330786964046,FUNC
1759,K,Q,p.K1759Q,Missense,0.272969812525532,FUNC
1759,K,E,p.K1759E,Missense,0.156731173606176,FUNC
1759,K,*,p.K1759*,Nonsense,-1.83354615516074,LOF
1759,K,T,p.K1759T,Missense,-0.25985222304398,FUNC
1759,K,R,p.K1759R,Missense,-0.0544160453697364,FUNC
1759,K,M,p.K1759M,Missense,0.379864410484195,FUNC
1759,K,K,p.K1759=,Splice region,-0.116965298488125,FUNC
1759,K,N,p.K1759N,Missense,-0.434461348117887,FUNC
1759,K,N,p.K1759N,Missense,0.0367403488744273,FUNC
1760,I,L,p.I1760L,Missense,-0.192788068985967,FUNC
1760,I,V,p.I1760V,Missense,-0.198692768109475,FUNC
1760,I,F,p.I1760F,Missense,-0.896258270912813,INT
1760,I,N,p.I1760N,Missense,-2.18199371175616,LOF
1760,I,T,p.I1760T,Missense,-2.60528794912708,LOF
1760,I,S,p.I1760S,Missense,-2.27112698644693,LOF
1760,I,I,p.I1760=,Splice region,-0.0308862862572565,FUNC
1760,I,M,p.I1760M,Missense,-0.167247724855025,FUNC
1760,I,I,p.I1760=,Splice region,-0.200177526958376,FUNC
1761,F,I,p.F1761I,Missense,-3.43496065672824,LOF
1761,F,L,p.F1761L,Missense,-0.0465529055170588,FUNC
1761,F,V,p.F1761V,Missense,-2.66153763520429,LOF
1761,F,Y,p.F1761Y,Missense,-1.03447820735947,INT
1761,F,S,p.F1761S,Missense,-3.08152848351391,LOF
1761,F,C,p.F1761C,Missense,-3.00072288720189,LOF
1761,F,L,p.F1761L,Missense,-0.0801007712599249,FUNC
1761,F,L,p.F1761L,Missense,-0.08594144139747,FUNC
1761,F,F,p.F1761=,Synonymous,-0.0645673602579033,FUNC
1762,R,R,p.R1762=,Synonymous,-0.0194075420398023,FUNC
1762,R,G,p.R1762G,Missense,-0.176011985228304,FUNC
1762,R,W,p.R1762W,Missense,0.246660900229952,FUNC
1762,R,K,p.R1762K,Missense,-0.142165264181613,FUNC
1762,R,T,p.R1762T,Missense,-0.287184713417449,FUNC
1762,R,M,p.R1762M,Missense,0.264115310641033,FUNC
1762,R,R,p.R1762=,Synonymous,-0.138422538315462,FUNC
1762,R,S,p.R1762S,Missense,0.111612808413628,FUNC
1762,R,S,p.R1762S,Missense,-0.0296905321365545,FUNC
1763,G,R,p.G1763R,Missense,-0.664336514868902,FUNC
1763,G,A,p.G1763A,Missense,0.636291742908012,FUNC
1763,G,V,p.G1763V,Missense,-1.83063676069214,LOF
1764,L,I,p.L1764I,Missense,-0.457075645766635,FUNC
1764,L,V,p.L1764V,Missense,-0.50267331622739,FUNC
1764,L,Q,p.L1764Q,Missense,-1.68158410922318,LOF
1764,L,P,p.L1764P,Missense,-1.98674456258502,LOF
1764,L,L,p.L1764=,Synonymous,0.608478573981982,FUNC
1764,L,L,p.L1764=,Synonymous,-0.510517082915677,FUNC
1764,L,L,p.L1764=,Synonymous,0.360960109789099,FUNC
1765,E,K,p.E1765K,Missense,-0.102273747831075,FUNC
1765,E,Q,p.E1765Q,Missense,-0.450121557831173,FUNC
1765,E,*,p.E1765*,Nonsense,-3.00762556456117,LOF
1765,E,A,p.E1765A,Missense,-0.20786189589508,FUNC
1765,E,G,p.E1765G,Missense,-0.945497358092497,INT
1765,E,V,p.E1765V,Missense,-0.197631605232239,FUNC
1765,E,D,p.E1765D,Missense,-0.0283618276029502,FUNC
1765,E,E,p.E1765=,Synonymous,0.72324306421002,FUNC
1765,E,D,p.E1765D,Missense,-0.129447079290475,FUNC
1766,I,L,p.I1766L,Missense,0.275411155256308,FUNC
1766,I,V,p.I1766V,Missense,-0.0279998265069619,FUNC
1766,I,F,p.I1766F,Missense,-0.248929789313465,FUNC
1766,I,N,p.I1766N,Missense,-2.94742785786032,LOF
1766,I,T,p.I1766T,Missense,-2.27267688131885,LOF
1766,I,S,p.I1766S,Missense,-1.8322684014954,LOF
1766,I,I,p.I1766=,Synonymous,-0.0991309823650213,FUNC
1766,I,M,p.I1766M,Missense,-0.314915848450392,FUNC
1766,I,I,p.I1766=,Synonymous,-0.0681187451921228,FUNC
1767,C,S,p.C1767S,Missense,-0.237880809362786,FUNC
1767,C,R,p.C1767R,Missense,-1.02352073149176,INT
1767,C,G,p.C1767G,Missense,-0.961465888922714,INT
1767,C,Y,p.C1767Y,Missense,-0.0184612943148304,FUNC
1767,C,S,p.C1767S,Missense,-0.966362391806273,INT
1767,C,F,p.C1767F,Missense,-0.0374273287899096,FUNC
1767,C,*,p.C1767*,Nonsense,-2.10905999043964,LOF
1767,C,C,p.C1767=,Synonymous,0.598969346547234,FUNC
1767,C,W,p.C1767W,Missense,-1.19549502227278,INT
1768,C,S,p.C1768S,Missense,-0.960079620676957,INT
1768,C,R,p.C1768R,Missense,-1.22753279038279,INT
1768,C,G,p.C1768G,Missense,-0.967951041146808,INT
1768,C,Y,p.C1768Y,Missense,-0.735895408178438,FUNC
1768,C,S,p.C1768S,Missense,-0.513420934838165,FUNC
1768,C,F,p.C1768F,Missense,-1.62308369795572,LOF
1768,C,*,p.C1768*,Nonsense,-2.19749428762657,LOF
1768,C,W,p.C1768W,Missense,-1.88372206453878,LOF
1768,C,C,p.C1768=,Synonymous,-0.25607832052774,FUNC
1769,Y,N,p.Y1769N,Missense,-0.174143411841224,FUNC
1769,Y,D,p.Y1769D,Missense,-1.75469164079008,LOF
1769,Y,S,p.Y1769S,Missense,-0.454148626569923,FUNC
1769,Y,C,p.Y1769C,Missense,-0.848123415234062,INT
1769,Y,F,p.Y1769F,Missense,0.22251304940389,FUNC
1769,Y,*,p.Y1769*,Nonsense,-2.17809858141866,LOF
1769,Y,Y,p.Y1769=,Synonymous,0.24984485549242,FUNC
1769,Y,*,p.Y1769*,Nonsense,-3.39490411129478,LOF
1770,G,R,p.G1770R,Missense,-1.26337029729486,INT
1770,G,R,p.G1770R,Missense,-1.48613141102459,LOF
1770,G,W,p.G1770W,Missense,-2.72697900429605,LOF
1770,G,E,p.G1770E,Missense,-0.241805340237675,FUNC
1770,G,A,p.G1770A,Missense,0.177727282870971,FUNC
1770,G,V,p.G1770V,Missense,-2.59802661440298,LOF
1770,G,G,p.G1770=,Synonymous,0.107836351717778,FUNC
1770,G,G,p.G1770=,Synonymous,-0.265284053798021,FUNC
1770,G,G,p.G1770=,Synonymous,0.18287107035385,FUNC
1771,P,T,p.P1771T,Missense,-0.582526407250707,FUNC
1771,P,A,p.P1771A,Missense,-0.660597064599592,FUNC
1771,P,S,p.P1771S,Missense,0.636000093760666,FUNC
1771,P,H,p.P1771H,Missense,-0.187415676059514,FUNC
1771,P,R,p.P1771R,Missense,-0.472155007274975,FUNC
1771,P,L,p.P1771L,Missense,-0.708448452085458,FUNC
1771,P,P,p.P1771=,Synonymous,-0.172579036031252,FUNC
1771,P,P,p.P1771=,Synonymous,0.667129686881808,FUNC
1771,P,P,p.P1771=,Synonymous,-0.400377067470858,FUNC
1772,F,I,p.F1772I,Missense,-0.203447138190926,FUNC
1772,F,L,p.F1772L,Missense,0.0181704028809614,FUNC
1772,F,V,p.F1772V,Missense,-1.01975228776749,INT
1772,F,Y,p.F1772Y,Missense,0.0528637204763113,FUNC
1772,F,S,p.F1772S,Missense,-0.104820760430005,FUNC
1772,F,C,p.F1772C,Missense,-0.318746863121226,FUNC
1772,F,L,p.F1772L,Missense,-0.681683377932247,FUNC
1772,F,F,p.F1772=,Synonymous,-0.391263301347585,FUNC
1773,T,P,p.T1773P,Missense,-0.067303491955124,FUNC
1773,T,A,p.T1773A,Missense,-0.986490293099587,INT
1773,T,S,p.T1773S,Missense,0.394609623070237,FUNC
1773,T,N,p.T1773N,Missense,-0.507254588677644,FUNC
1773,T,S,p.T1773S,Missense,-0.785410271870885,INT
1773,T,I,p.T1773I,Missense,0.200455715036385,FUNC
1773,T,T,p.T1773=,Synonymous,0.00158943110063844,FUNC
1773,T,T,p.T1773=,Synonymous,0.240010504489872,FUNC
1773,T,T,p.T1773=,Synonymous,-0.476490934181509,FUNC
1774,N,H,p.N1774H,Missense,0.136919874414982,FUNC
1774,N,D,p.N1774D,Missense,0.0667323376042325,FUNC
1774,N,Y,p.N1774Y,Missense,-0.0450667494950961,FUNC
1774,N,T,p.N1774T,Missense,0.00328023071677523,FUNC
1774,N,S,p.N1774S,Missense,-0.108641712088229,FUNC
1774,N,I,p.N1774I,Missense,-0.143580171930243,FUNC
1774,N,K,p.N1774K,Missense,-0.0160304513345875,FUNC
1774,N,K,p.N1774K,Missense,-0.0255105890039917,FUNC
1774,N,N,p.N1774=,Synonymous,-0.501709435551784,FUNC
1775,M,L,p.M1775L,Missense,0.159622888299092,FUNC
1775,M,V,p.M1775V,Missense,-1.52204230150555,LOF
1775,M,L,p.M1775L,Missense,0.0926336793468094,FUNC
1775,M,K,p.M1775K,Missense,-1.83186236584358,LOF
1775,M,T,p.M1775T,Missense,-0.703426201074615,FUNC
1775,M,R,p.M1775R,Missense,-1.39263844476786,LOF
1775,M,I,p.M1775I,Missense,-0.299537464070136,FUNC
1775,M,I,p.M1775I,Missense,-1.03339957743026,INT
1775,M,I,p.M1775I,Missense,-0.844174268411832,INT
1776,P,T,p.P1776T,Missense,-0.151370594978487,FUNC
1776,P,A,p.P1776A,Missense,-0.297481909996896,FUNC
1776,P,S,p.P1776S,Missense,-0.463819845410984,FUNC
1776,P,H,p.P1776H,Missense,0.332097384608235,FUNC
1776,P,R,p.P1776R,Missense,-0.0777552646360438,FUNC
1776,P,L,p.P1776L,Missense,-0.365363312214972,FUNC
1776,P,P,p.P1776=,Synonymous,-0.640079764971539,FUNC
1776,P,P,p.P1776=,Synonymous,0.305799565843194,FUNC
1776,P,P,p.P1776=,Synonymous,-0.56775260589364,FUNC
1777,T,P,p.T1777P,Missense,0.0914192095487446,FUNC
1777,T,A,p.T1777A,Missense,0.115434624138304,FUNC
1777,T,S,p.T1777S,Missense,-0.0170110028106307,FUNC
1777,T,K,p.T1777K,Missense,-0.230527311497293,FUNC
1777,T,R,p.T1777R,Missense,-0.25998476982797,FUNC
1777,T,I,p.T1777I,Missense,-0.453445016190339,FUNC
1777,T,T,p.T1777=,Splice region,0.600079459902136,FUNC
1777,T,T,p.T1777=,Splice region,-0.231539314770227,FUNC
1777,T,T,p.T1777=,Splice region,0.173090797763497,FUNC
1778,D,N,p.D1778N,Missense,-1.01795048355751,INT
1778,D,Y,p.D1778Y,Missense,-1.05268035266478,INT
1778,D,A,p.D1778A,Missense,0.0479717100761646,FUNC
1778,D,G,p.D1778G,Missense,-0.0931977965380277,FUNC
1778,D,V,p.D1778V,Missense,0.0108527643226936,FUNC
1778,D,E,p.D1778E,Missense,-0.20823704088306,FUNC
1778,D,D,p.D1778=,Splice region,-0.26016954677242,FUNC
1778,D,E,p.D1778E,Missense,0.0728414637533551,FUNC
1779,Q,K,p.Q1779K,Missense,0.174697663649451,FUNC
1779,Q,E,p.Q1779E,Missense,-0.201378826174088,FUNC
1779,Q,*,p.Q1779*,Nonsense,-2.47967527520024,LOF
1779,Q,P,p.Q1779P,Missense,-0.597503847600514,FUNC
1779,Q,R,p.Q1779R,Missense,-0.0827082122920327,FUNC
1779,Q,L,p.Q1779L,Missense,0.0819590983078264,FUNC
1779,Q,H,p.Q1779H,Missense,0.102366918162689,FUNC
1779,Q,Q,p.Q1779=,Synonymous,0.362753046878947,FUNC
1779,Q,H,p.Q1779H,Missense,0.381886338844836,FUNC
1780,L,V,p.L1780V,Missense,-0.690953041643596,FUNC
1780,L,P,p.L1780P,Missense,-2.35494389501738,LOF
1780,L,R,p.L1780R,Missense,-1.98265374549964,LOF
1781,E,K,p.E1781K,Missense,0.12233070374617,FUNC
1781,E,Q,p.E1781Q,Missense,0.192824553562926,FUNC
1781,E,*,p.E1781*,Nonsense,-1.61962076935611,LOF
1781,E,A,p.E1781A,Missense,0.400263043235692,FUNC
1781,E,V,p.E1781V,Missense,0.205498426858397,FUNC
1781,E,D,p.E1781D,Missense,0.150240979150035,FUNC
1781,E,E,p.E1781=,Synonymous,0.320884870419351,FUNC
1781,E,D,p.E1781D,Missense,0.0691358948966604,FUNC
1782,W,R,p.W1782R,Missense,-0.00104627961552295,FUNC
1782,W,R,p.W1782R,Missense,0.301775217364129,FUNC
1782,W,G,p.W1782G,Missense,0.00575538769405902,FUNC
1782,W,*,p.W1782*,Nonsense,-2.1074562156672,LOF
1782,W,S,p.W1782S,Missense,0.180529842763142,FUNC
1782,W,L,p.W1782L,Missense,0.00388658804903696,FUNC
1782,W,*,p.W1782*,Nonsense,-2.81319864574004,LOF
1782,W,C,p.W1782C,Missense,-0.17742550575048,FUNC
1782,W,C,p.W1782C,Missense,-0.0381111812813275,FUNC
1783,M,L,p.M1783L,Missense,0.13337933326075,FUNC
1783,M,V,p.M1783V,Missense,-0.114052490451158,FUNC
1783,M,L,p.M1783L,Missense,0.0424732913758367,FUNC
1783,M,K,p.M1783K,Missense,-1.512336819026,LOF
1783,M,T,p.M1783T,Missense,-0.442333511040748,FUNC
1783,M,R,p.M1783R,Missense,-2.11365295533474,LOF
1783,M,I,p.M1783I,Missense,0.214041727107737,FUNC
1783,M,I,p.M1783I,Missense,-0.238648890470428,FUNC
1783,M,I,p.M1783I,Missense,-0.14570390441998,FUNC
1784,V,I,p.V1784I,Missense,-0.0522352088267999,FUNC
1784,V,L,p.V1784L,Missense,0.0646624586213577,FUNC
1784,V,L,p.V1784L,Missense,-0.18648893535765,FUNC
1784,V,E,p.V1784E,Missense,-2.0827200162814,LOF
1784,V,A,p.V1784A,Missense,0.288345831228837,FUNC
1784,V,G,p.V1784G,Missense,-0.482147505219213,FUNC
1784,V,V,p.V1784=,Synonymous,-0.0265484284790486,FUNC
1784,V,V,p.V1784=,Synonymous,-0.0263170140682868,FUNC
1784,V,V,p.V1784=,Synonymous,0.53807434185041,FUNC
1785,Q,K,p.Q1785K,Missense,-0.283400304529952,FUNC
1785,Q,E,p.Q1785E,Missense,0.269408296524204,FUNC
1785,Q,*,p.Q1785*,Nonsense,-1.62290738466627,LOF
1785,Q,P,p.Q1785P,Missense,-1.5255604320955,LOF
1785,Q,R,p.Q1785R,Missense,0.103971130279797,FUNC
1785,Q,L,p.Q1785L,Missense,0.0647997066724299,FUNC
1785,Q,Q,p.Q1785=,Synonymous,0.0784180344339319,FUNC
1785,Q,H,p.Q1785H,Missense,-0.357940749529229,FUNC
1785,Q,H,p.Q1785H,Missense,0.322514084293061,FUNC
1786,L,M,p.L1786M,Missense,-0.17741061696737,FUNC
1786,L,V,p.L1786V,Missense,-0.196547915290319,FUNC
1786,L,L,p.L1786=,Synonymous,0.160631280794563,FUNC
1786,L,Q,p.L1786Q,Missense,-0.200929901328434,FUNC
1786,L,P,p.L1786P,Missense,-1.52151054562003,LOF
1786,L,R,p.L1786R,Missense,-0.151024584442163,FUNC
1786,L,L,p.L1786=,Synonymous,0.150391968364462,FUNC
1786,L,L,p.L1786=,Synonymous,-0.0314855440941615,FUNC
1786,L,L,p.L1786=,Synonymous,-0.146479584587786,FUNC
1787,C,S,p.C1787S,Missense,0.0694597491461825,FUNC
1787,C,R,p.C1787R,Missense,-1.92561847816988,LOF
1787,C,G,p.C1787G,Missense,0.158224375208038,FUNC
1787,C,Y,p.C1787Y,Missense,-1.75624865950192,LOF
1787,C,S,p.C1787S,Missense,-0.309405568264593,FUNC
1787,C,F,p.C1787F,Missense,-0.299372080620328,FUNC
1787,C,*,p.C1787*,Nonsense,-1.7550700415573,LOF
1787,C,C,p.C1787=,Synonymous,0.149741365309759,FUNC
1787,C,W,p.C1787W,Missense,-1.95535837760952,LOF
1788,G,S,p.G1788S,Missense,-1.35252332130451,LOF
1788,G,R,p.G1788R,Missense,-2.18578715534141,LOF
1788,G,C,p.G1788C,Missense,-1.88570416514307,LOF
1788,G,D,p.G1788D,Missense,-0.693108211684985,FUNC
1788,G,A,p.G1788A,Missense,-1.41213169676715,LOF
1788,G,V,p.G1788V,Missense,-1.67971518079398,LOF
1788,G,G,p.G1788=,Synonymous,0.25628170158869,FUNC
1788,G,G,p.G1788=,Synonymous,0.0559480474136519,FUNC
1788,G,G,p.G1788=,Synonymous,-0.0460176718875618,FUNC
1789,A,T,p.A1789T,Missense,-2.13900446359407,LOF
1789,A,P,p.A1789P,Missense,-1.67132779442868,LOF
1789,A,S,p.A1789S,Missense,-0.439408021397876,FUNC
1789,A,D,p.A1789D,Missense,-2.49789791552294,LOF
1789,A,G,p.A1789G,Missense,-0.161095734093141,FUNC
1789,A,V,p.A1789V,Missense,-1.99955294338856,LOF
1789,A,A,p.A1789=,Synonymous,0.186804513870578,FUNC
1789,A,A,p.A1789=,Synonymous,0.0385615561256449,FUNC
1789,A,A,p.A1789=,Synonymous,-0.0053099751216397,FUNC
1790,S,T,p.S1790T,Missense,0.167673099754918,FUNC
1790,S,P,p.S1790P,Missense,-0.545062213705706,FUNC
1790,S,A,p.S1790A,Missense,0.250685590082046,FUNC
1790,S,Y,p.S1790Y,Missense,-0.351389323900309,FUNC
1790,S,C,p.S1790C,Missense,0.159635608115002,FUNC
1790,S,F,p.S1790F,Missense,-0.243343660438374,FUNC
1790,S,S,p.S1790=,Synonymous,0.0203886429398427,FUNC
1790,S,S,p.S1790=,Synonymous,-0.090643454642316,FUNC
1790,S,S,p.S1790=,Synonymous,0.116292496196534,FUNC
1791,V,M,p.V1791M,Missense,-0.252402919340413,FUNC
1791,V,L,p.V1791L,Missense,-0.102589136564514,FUNC
1791,V,L,p.V1791L,Missense,0.0372197539809666,FUNC
1791,V,E,p.V1791E,Missense,-1.18900378766452,INT
1791,V,A,p.V1791A,Missense,0.185419112883371,FUNC
1791,V,G,p.V1791G,Missense,-0.654299842902055,FUNC
1791,V,V,p.V1791=,Synonymous,0.252161816435646,FUNC
1791,V,V,p.V1791=,Synonymous,-0.208536721264177,FUNC
1791,V,V,p.V1791=,Synonymous,0.27743967754371,FUNC
1792,V,M,p.V1792M,Missense,-0.136814696599983,FUNC
1792,V,L,p.V1792L,Missense,-0.323216046739691,FUNC
1792,V,L,p.V1792L,Missense,0.0892212992989589,FUNC
1792,V,E,p.V1792E,Missense,-1.0339054301172,INT
1792,V,A,p.V1792A,Missense,0.290276501539217,FUNC
1792,V,G,p.V1792G,Missense,-0.585138825147941,FUNC
1792,V,V,p.V1792=,Synonymous,0.121408549265363,FUNC
1792,V,V,p.V1792=,Synonymous,-0.286496849221273,FUNC
1792,V,V,p.V1792=,Synonymous,-0.266690967111432,FUNC
1793,K,Q,p.K1793Q,Missense,0.190832525180751,FUNC
1793,K,E,p.K1793E,Missense,0.140358150458954,FUNC
1793,K,*,p.K1793*,Nonsense,-1.68212999394174,LOF
1793,K,T,p.K1793T,Missense,0.304856630864488,FUNC
1793,K,R,p.K1793R,Missense,0.472239647341756,FUNC
1793,K,M,p.K1793M,Missense,-0.350282462891759,FUNC
1793,K,K,p.K1793=,Synonymous,-0.0183786170833556,FUNC
1793,K,N,p.K1793N,Missense,-0.0941571679964586,FUNC
1793,K,N,p.K1793N,Missense,-0.876197532692981,INT
1794,E,K,p.E1794K,Missense,-0.191608108551811,FUNC
1794,E,Q,p.E1794Q,Missense,0.0884711697837991,FUNC
1794,E,*,p.E1794*,Nonsense,-1.89985330876262,LOF
1794,E,A,p.E1794A,Missense,0.133261067224365,FUNC
1794,E,G,p.E1794G,Missense,0.494525047157639,FUNC
1794,E,V,p.E1794V,Missense,-0.277387579228496,FUNC
1794,E,E,p.E1794=,Synonymous,-0.139960541419263,FUNC
1794,E,D,p.E1794D,Missense,-0.324753024351241,FUNC
1794,E,D,p.E1794D,Missense,-0.0815950186402554,FUNC
1795,L,I,p.L1795I,Missense,-0.370652929013699,FUNC
1795,L,V,p.L1795V,Missense,-0.0497304980816789,FUNC
1795,L,F,p.L1795F,Missense,0.193792114752982,FUNC
1795,L,H,p.L1795H,Missense,-0.161827929847202,FUNC
1795,L,P,p.L1795P,Missense,0.185247953652887,FUNC
1795,L,R,p.L1795R,Missense,0.0327626382503446,FUNC
1795,L,L,p.L1795=,Synonymous,-0.0819982878013457,FUNC
1795,L,L,p.L1795=,Synonymous,0.263766498253102,FUNC
1795,L,L,p.L1795=,Synonymous,0.0146313992962136,FUNC
1796,S,T,p.S1796T,Missense,-0.131191208390193,FUNC
1796,S,P,p.S1796P,Missense,-0.158763871414765,FUNC
1796,S,A,p.S1796A,Missense,-0.0612245229886579,FUNC
1796,S,*,p.S1796*,Nonsense,-3.21317734685245,LOF
1796,S,*,p.S1796*,Nonsense,-2.44266456822478,LOF
1796,S,L,p.S1796L,Missense,-0.78358701710021,INT
1796,S,S,p.S1796=,Synonymous,-0.281415025719808,FUNC
1796,S,S,p.S1796=,Synonymous,0.216087834816867,FUNC
1796,S,S,p.S1796=,Synonymous,-0.23606958414134,FUNC
1797,S,T,p.S1797T,Missense,-0.126059917510523,FUNC
1797,S,P,p.S1797P,Missense,0.0394864670509823,FUNC
1797,S,A,p.S1797A,Missense,0.132073995505377,FUNC
1797,S,*,p.S1797*,Nonsense,-2.11762035319046,LOF
1797,S,*,p.S1797*,Nonsense,-2.51527953598369,LOF
1797,S,L,p.S1797L,Missense,-0.0936897989799215,FUNC
1797,S,S,p.S1797=,Synonymous,-0.147882567306313,FUNC
1797,S,S,p.S1797=,Synonymous,0.13210564418968,FUNC
1797,S,S,p.S1797=,Synonymous,0.0619342509747516,FUNC
1798,F,I,p.F1798I,Missense,-0.202967369744968,FUNC
1798,F,L,p.F1798L,Missense,0.0855003195549869,FUNC
1798,F,V,p.F1798V,Missense,-0.209132542877285,FUNC
1798,F,Y,p.F1798Y,Missense,-0.01276580343985,FUNC
1798,F,S,p.F1798S,Missense,0.109082853168178,FUNC
1798,F,C,p.F1798C,Missense,-0.0452733425154589,FUNC
1798,F,L,p.F1798L,Missense,-0.398617695553226,FUNC
1798,F,L,p.F1798L,Missense,0.0619887473399611,FUNC
1798,F,F,p.F1798=,Synonymous,-0.176393722554746,FUNC
1799,T,P,p.T1799P,Missense,0.0695131900652219,FUNC
1799,T,A,p.T1799A,Missense,0.197311230451047,FUNC
1799,T,S,p.T1799S,Missense,0.262206100343005,FUNC
1799,T,N,p.T1799N,Missense,-0.281580311872448,FUNC
1799,T,S,p.T1799S,Missense,0.125790879107877,FUNC
1799,T,I,p.T1799I,Missense,0.0560736391656419,FUNC
1799,T,T,p.T1799=,Synonymous,-0.141839883546775,FUNC
1799,T,T,p.T1799=,Synonymous,-0.0216323304414379,FUNC
1799,T,T,p.T1799=,Synonymous,0.226322779507549,FUNC
1800,L,I,p.L1800I,Missense,-0.000404225082606239,FUNC
1800,L,V,p.L1800V,Missense,-0.13627949259987,FUNC
1800,L,F,p.L1800F,Missense,-0.0547760040777577,FUNC
1800,L,H,p.L1800H,Missense,0.163739165110723,FUNC
1800,L,P,p.L1800P,Missense,0.171427448557989,FUNC
1800,L,R,p.L1800R,Missense,0.0201724922153654,FUNC
1800,L,L,p.L1800=,Synonymous,0.0249216122095287,FUNC
1800,L,L,p.L1800=,Synonymous,0.137595280735211,FUNC
1800,L,L,p.L1800=,Synonymous,-0.482915117565883,FUNC
1801,G,S,p.G1801S,Missense,0.0929733933226665,FUNC
1801,G,R,p.G1801R,Missense,-0.261908995635857,FUNC
1801,G,C,p.G1801C,Missense,-0.127259499587978,FUNC
1801,G,D,p.G1801D,Missense,0.042955773559517,FUNC
1801,G,A,p.G1801A,Missense,0.00774047622864239,FUNC
1801,G,V,p.G1801V,Missense,0.265168854969305,FUNC
1801,G,G,p.G1801=,Synonymous,-0.00726933529411242,FUNC
1801,G,G,p.G1801=,Synonymous,-0.129638009011805,FUNC
1801,G,G,p.G1801=,Synonymous,0.186084566746642,FUNC
1802,T,P,p.T1802P,Missense,0.305814752810961,FUNC
1802,T,A,p.T1802A,Missense,0.0459927057873582,FUNC
1802,T,S,p.T1802S,Missense,0.0748657246484658,FUNC
1802,T,K,p.T1802K,Missense,-0.354782146554933,FUNC
1802,T,R,p.T1802R,Missense,-0.060562918187704,FUNC
1802,T,I,p.T1802I,Missense,0.183191305472956,FUNC
1802,T,T,p.T1802=,Splice region,-0.610873467469799,FUNC
1802,T,T,p.T1802=,Splice region,0.162007829151227,FUNC
1802,T,T,p.T1802=,Splice region,-0.18437850995376,FUNC
1803,G,S,p.G1803S,Missense,-0.320508703475903,FUNC
1803,G,R,p.G1803R,Missense,0.104268267938043,FUNC
1803,G,C,p.G1803C,Missense,0.309842650307981,FUNC
1803,G,D,p.G1803D,Missense,-1.07093036779495,INT
1803,G,A,p.G1803A,Missense,0.0151078043175211,FUNC
1803,G,V,p.G1803V,Missense,-0.349508563263171,FUNC
1803,G,G,p.G1803=,Splice region,0.116030430149339,FUNC
1803,G,G,p.G1803=,Splice region,0.0303700158748514,FUNC
1803,G,G,p.G1803=,Splice region,0.0773558129758903,FUNC
1804,V,I,p.V1804I,Missense,0.0581484754151494,FUNC
1804,V,L,p.V1804L,Missense,-0.580450234524992,FUNC
1804,V,F,p.V1804F,Missense,0.556759821611326,FUNC
1804,V,D,p.V1804D,Missense,0.429372531464068,FUNC
1804,V,A,p.V1804A,Missense,0.0815834702117477,FUNC
1804,V,G,p.V1804G,Missense,-0.697272170920749,FUNC
1804,V,V,p.V1804=,Synonymous,-0.601048325168998,FUNC
1804,V,V,p.V1804=,Synonymous,0.040277842360585,FUNC
1804,V,V,p.V1804=,Synonymous,0.455129914467093,FUNC
1805,H,N,p.H1805N,Missense,0.140889196289081,FUNC
1805,H,D,p.H1805D,Missense,0.211689664596731,FUNC
1805,H,Y,p.H1805Y,Missense,0.198364116512171,FUNC
1805,H,P,p.H1805P,Missense,-0.0838730473504482,FUNC
1805,H,R,p.H1805R,Missense,-0.0100644573327441,FUNC
1805,H,L,p.H1805L,Missense,0.276406041152877,FUNC
1805,H,Q,p.H1805Q,Missense,-0.29132380924291,FUNC
1805,H,Q,p.H1805Q,Missense,-0.109804786913623,FUNC
1805,H,H,p.H1805=,Synonymous,0.213177011177558,FUNC
1806,P,T,p.P1806T,Missense,-0.30418704230611,FUNC
1806,P,A,p.P1806A,Missense,0.0981067115118336,FUNC
1806,P,S,p.P1806S,Missense,0.477544138223875,FUNC
1806,P,Q,p.P1806Q,Missense,0.0738415973464122,FUNC
1806,P,R,p.P1806R,Missense,0.160857415316131,FUNC
1806,P,L,p.P1806L,Missense,-0.20381749392313,FUNC
1806,P,P,p.P1806=,Synonymous,0.122787189815673,FUNC
1806,P,P,p.P1806=,Synonymous,-0.0890474031569899,FUNC
1806,P,P,p.P1806=,Synonymous,0.332185979688528,FUNC
1807,I,L,p.I1807L,Missense,0.177009280841274,FUNC
1807,I,V,p.I1807V,Missense,0.161589836890456,FUNC
1807,I,F,p.I1807F,Missense,-1.12507013556553,INT
1807,I,N,p.I1807N,Missense,-1.74149703360338,LOF
1807,I,T,p.I1807T,Missense,-0.260029673632726,FUNC
1807,I,S,p.I1807S,Missense,-1.93277430656549,LOF
1807,I,I,p.I1807=,Synonymous,-0.375639698163221,FUNC
1807,I,I,p.I1807=,Synonymous,-0.428161082041069,FUNC
1807,I,M,p.I1807M,Missense,0.165225198661028,FUNC
1808,V,L,p.V1808L,Missense,-0.227223408961075,FUNC
1808,V,A,p.V1808A,Missense,-0.798819225404382,INT
1808,V,G,p.V1808G,Missense,-1.93008814099227,LOF
1809,V,I,p.V1809I,Missense,-0.216144901410392,FUNC
1809,V,D,p.V1809D,Missense,-1.35490391827617,LOF
1809,V,A,p.V1809A,Missense,-1.64995829623803,LOF
1809,V,V,p.V1809=,Synonymous,-0.307997887176628,FUNC
1809,V,V,p.V1809=,Synonymous,0.149097538786792,FUNC
1809,V,V,p.V1809=,Synonymous,0.547412873058203,FUNC
1810,V,M,p.V1810M,Missense,-0.477757820634248,FUNC
1810,V,L,p.V1810L,Missense,-0.135301414304995,FUNC
1810,V,L,p.V1810L,Missense,-0.121348500278939,FUNC
1810,V,E,p.V1810E,Missense,-1.56364067852353,LOF
1810,V,A,p.V1810A,Missense,-0.0362606384097366,FUNC
1810,V,G,p.V1810G,Missense,-3.37388079968849,LOF
1810,V,V,p.V1810=,Synonymous,0.533511113650839,FUNC
1810,V,V,p.V1810=,Synonymous,-2.81771291125752,LOF
1810,V,V,p.V1810=,Synonymous,-0.741666777844507,FUNC
1811,Q,K,p.Q1811K,Missense,-2.06191114250477,LOF
1811,Q,E,p.Q1811E,Missense,-0.0765758519640052,FUNC
1811,Q,*,p.Q1811*,Nonsense,-1.2578347807606,INT
1811,Q,P,p.Q1811P,Missense,-1.94690150805163,LOF
1811,Q,R,p.Q1811R,Missense,-1.71150218576215,LOF
1811,Q,L,p.Q1811L,Missense,-3.42015814678606,LOF
1811,Q,Q,p.Q1811=,Synonymous,0.123846216752144,FUNC
1811,Q,H,p.Q1811H,Missense,-0.747776959258352,FUNC
1811,Q,H,p.Q1811H,Missense,-0.265803184156264,FUNC
1812,P,T,p.P1812T,Missense,-0.0747085351851316,FUNC
1812,P,A,p.P1812A,Missense,-2.75730524006307,LOF
1812,P,S,p.P1812S,Missense,-0.326462941050817,FUNC
1812,P,Q,p.P1812Q,Missense,-0.87911228791937,INT
1812,P,R,p.P1812R,Missense,0.261310921067065,FUNC
1812,P,L,p.P1812L,Missense,-0.765334600703459,INT
1812,P,P,p.P1812=,Synonymous,0.0362468735692044,FUNC
1812,P,P,p.P1812=,Synonymous,0.186991589730266,FUNC
1812,P,P,p.P1812=,Synonymous,-0.224430655789883,FUNC
1813,D,N,p.D1813N,Missense,-0.142261663939848,FUNC
1813,D,H,p.D1813H,Missense,-0.981230415384132,INT
1813,D,Y,p.D1813Y,Missense,-1.31630485647323,INT
1813,D,A,p.D1813A,Missense,0.0252273320146534,FUNC
1813,D,G,p.D1813G,Missense,0.210341159534457,FUNC
1813,D,V,p.D1813V,Missense,-0.180560716114802,FUNC
1813,D,E,p.D1813E,Missense,-0.123269041897135,FUNC
1813,D,D,p.D1813=,Synonymous,0.0723609820404624,FUNC
1813,D,E,p.D1813E,Missense,-0.202936110123185,FUNC
1814,A,T,p.A1814T,Missense,-0.18071629810108,FUNC
1814,A,P,p.A1814P,Missense,-0.846765221867354,INT
1814,A,S,p.A1814S,Missense,-0.671084707363718,FUNC
1814,A,D,p.A1814D,Missense,-1.25491240157845,INT
1814,A,G,p.A1814G,Missense,-1.37729254003792,LOF
1814,A,V,p.A1814V,Missense,-0.359948471675103,FUNC
1814,A,A,p.A1814=,Synonymous,-0.186658939575152,FUNC
1814,A,A,p.A1814=,Synonymous,-0.653707677962266,FUNC
1814,A,A,p.A1814=,Synonymous,0.624965266441664,FUNC
1815,W,R,p.W1815R,Missense,-0.602917276919085,FUNC
1815,W,R,p.W1815R,Missense,-0.365140498078149,FUNC
1815,W,G,p.W1815G,Missense,-0.624105914918508,FUNC
1815,W,*,p.W1815*,Nonsense,-1.58448902074217,LOF
1815,W,S,p.W1815S,Missense,-1.54969753079545,LOF
1815,W,L,p.W1815L,Missense,0.0358900469836761,FUNC
1815,W,*,p.W1815*,Nonsense,-2.73431474337157,LOF
1815,W,C,p.W1815C,Missense,-4.59169894132378,LOF
1815,W,C,p.W1815C,Missense,-1.66682003220817,LOF
1816,T,P,p.T1816P,Missense,-0.302598612595167,FUNC
1816,T,A,p.T1816A,Missense,-0.0937200312476537,FUNC
1816,T,S,p.T1816S,Missense,-0.582124910532308,FUNC
1816,T,K,p.T1816K,Missense,-0.50509533799371,FUNC
1816,T,R,p.T1816R,Missense,0.0848726002519976,FUNC
1816,T,I,p.T1816I,Missense,0.018444786382987,FUNC
1816,T,T,p.T1816=,Synonymous,0.00132435330773251,FUNC
1816,T,T,p.T1816=,Synonymous,0.859885662660011,FUNC
1816,T,T,p.T1816=,Synonymous,0.0965304435751904,FUNC
1817,E,K,p.E1817K,Missense,0.12622695353046,FUNC
1817,E,Q,p.E1817Q,Missense,-0.478225312424512,FUNC
1817,E,*,p.E1817*,Nonsense,-2.60080914927399,LOF
1817,E,A,p.E1817A,Missense,0.310352544927213,FUNC
1817,E,G,p.E1817G,Missense,0.719011109277808,FUNC
1817,E,V,p.E1817V,Missense,-0.587397334883521,FUNC
1817,E,E,p.E1817=,Synonymous,0.130951836032382,FUNC
1817,E,D,p.E1817D,Missense,-0.645565909567874,FUNC
1817,E,D,p.E1817D,Missense,-0.107234786818994,FUNC
1818,D,N,p.D1818N,Missense,-0.0596667537912333,FUNC
1818,D,H,p.D1818H,Missense,-1.96668251565954,LOF
1818,D,Y,p.D1818Y,Missense,0.0295802372494833,FUNC
1818,D,A,p.D1818A,Missense,-0.628332847454398,FUNC
1818,D,G,p.D1818G,Missense,-3.16303530428822,LOF
1818,D,V,p.D1818V,Missense,0.155552918698498,FUNC
1818,D,E,p.D1818E,Missense,0.116922666390149,FUNC
1818,D,E,p.D1818E,Missense,0.163587351312571,FUNC
1818,D,D,p.D1818=,Synonymous,-0.118783422761102,FUNC
1819,N,H,p.N1819H,Missense,-0.4159574435229,FUNC
1819,N,D,p.N1819D,Missense,0.000534279097789327,FUNC
1819,N,Y,p.N1819Y,Missense,-0.449637787239626,FUNC
1819,N,T,p.N1819T,Missense,-0.279502933520711,FUNC
1819,N,S,p.N1819S,Missense,0.40875721687432,FUNC
1819,N,I,p.N1819I,Missense,-0.270928278794043,FUNC
1819,N,K,p.N1819K,Missense,-0.231764896321833,FUNC
1819,N,N,p.N1819=,Synonymous,0.449495997347053,FUNC
1819,N,K,p.N1819K,Missense,-0.0864385079311445,FUNC
1820,G,S,p.G1820S,Missense,-0.396620647728962,FUNC
1820,G,R,p.G1820R,Missense,-0.154003265804798,FUNC
1820,G,C,p.G1820C,Missense,-0.609895504542478,FUNC
1820,G,D,p.G1820D,Missense,-0.325765930686046,FUNC
1820,G,A,p.G1820A,Missense,-0.78442294561279,INT
1820,G,V,p.G1820V,Missense,0.262636792305302,FUNC
1820,G,G,p.G1820=,Synonymous,0.660780546618066,FUNC
1820,G,G,p.G1820=,Synonymous,-0.285622926112162,FUNC
1820,G,G,p.G1820=,Synonymous,-0.072365435977091,FUNC
1821,F,I,p.F1821I,Missense,-0.437724082218039,FUNC
1821,F,L,p.F1821L,Missense,-0.0705944057349995,FUNC
1821,F,V,p.F1821V,Missense,-0.195359256905534,FUNC
1821,F,Y,p.F1821Y,Missense,-0.0386873051563448,FUNC
1821,F,S,p.F1821S,Missense,-0.112501489145551,FUNC
1821,F,C,p.F1821C,Missense,-0.734628880173957,FUNC
1821,F,L,p.F1821L,Missense,-0.453237634054845,FUNC
1821,F,L,p.F1821L,Missense,-0.0985935653696425,FUNC
1821,F,F,p.F1821=,Synonymous,-0.0620096361859575,FUNC
1822,H,N,p.H1822N,Missense,0.219049202991851,FUNC
1822,H,D,p.H1822D,Missense,0.225013753860343,FUNC
1822,H,Y,p.H1822Y,Missense,-0.242424964962834,FUNC
1822,H,P,p.H1822P,Missense,0.00160083241910782,FUNC
1822,H,R,p.H1822R,Missense,-0.424960817864333,FUNC
1822,H,L,p.H1822L,Missense,-0.330819440615656,FUNC
1822,H,Q,p.H1822Q,Missense,0.0794694797845351,FUNC
1822,H,H,p.H1822=,Splice region,0.0318997293854854,FUNC
1822,H,Q,p.H1822Q,Missense,-0.081382851010922,FUNC
1823,A,T,p.A1823T,Missense,-3.1865190755667,LOF
1823,A,P,p.A1823P,Missense,-3.30464537023334,LOF
1823,A,S,p.A1823S,Missense,-3.64283083340989,LOF
1823,A,E,p.A1823E,Missense,0.135290185644148,FUNC
1823,A,G,p.A1823G,Missense,-0.841867943178274,INT
1823,A,V,p.A1823V,Missense,-0.438360205936103,FUNC
1823,A,A,p.A1823=,Splice region,0.0390698319616235,FUNC
1823,A,A,p.A1823=,Splice region,-0.497422730313804,FUNC
1823,A,A,p.A1823=,Splice region,-0.154681528549779,FUNC
1824,I,L,p.I1824L,Missense,-0.313789980136991,FUNC
1824,I,V,p.I1824V,Missense,-0.330562389135634,FUNC
1824,I,F,p.I1824F,Missense,-0.51001610838843,FUNC
1824,I,N,p.I1824N,Missense,-0.29359073484416,FUNC
1824,I,T,p.I1824T,Missense,-0.528084960333966,FUNC
1824,I,S,p.I1824S,Missense,-0.126433780195305,FUNC
1824,I,I,p.I1824=,Synonymous,0.0695896057211375,FUNC
1824,I,I,p.I1824=,Synonymous,0.0668076834531773,FUNC
1824,I,M,p.I1824M,Missense,-2.07801978551443,LOF
1825,G,R,p.G1825R,Missense,-0.205906394139239,FUNC
1825,G,R,p.G1825R,Missense,-0.0468092630879426,FUNC
1825,G,W,p.G1825W,Missense,-0.608895506587524,FUNC
1825,G,E,p.G1825E,Missense,-0.0107716612518232,FUNC
1825,G,A,p.G1825A,Missense,-0.0428738564007823,FUNC
1825,G,V,p.G1825V,Missense,-0.130113384362839,FUNC
1825,G,G,p.G1825=,Synonymous,0.0324423177634513,FUNC
1825,G,G,p.G1825=,Synonymous,-0.0210624152659631,FUNC
1825,G,G,p.G1825=,Synonymous,-0.753072752459166,INT
1826,Q,K,p.Q1826K,Missense,-0.0258904786315756,FUNC
1826,Q,E,p.Q1826E,Missense,0.0441739691511223,FUNC
1826,Q,*,p.Q1826*,Nonsense,-1.44251233142322,LOF
1826,Q,P,p.Q1826P,Missense,-0.0324057057312437,FUNC
1826,Q,R,p.Q1826R,Missense,0.0385125692046524,FUNC
1826,Q,L,p.Q1826L,Missense,-0.188283017525521,FUNC
1826,Q,Q,p.Q1826=,Synonymous,-0.614359996056815,FUNC
1826,Q,H,p.Q1826H,Missense,-0.583553197877685,FUNC
1826,Q,H,p.Q1826H,Missense,-0.438084188181349,FUNC
1827,M,L,p.M1827L,Missense,-0.252517317545388,FUNC
1827,M,V,p.M1827V,Missense,-0.276791005238962,FUNC
1827,M,L,p.M1827L,Missense,0.236500390874289,FUNC
1827,M,K,p.M1827K,Missense,-0.129843361578819,FUNC
1827,M,T,p.M1827T,Missense,0.0630260478167066,FUNC
1827,M,R,p.M1827R,Missense,-0.242181568873002,FUNC
1827,M,I,p.M1827I,Missense,-0.344383558747861,FUNC
1827,M,I,p.M1827I,Missense,-0.564045504521159,FUNC
1827,M,I,p.M1827I,Missense,-0.256728546446218,FUNC
1828,C,S,p.C1828S,Missense,-0.122869949653996,FUNC
1828,C,R,p.C1828R,Missense,-0.87561933503084,INT
1828,C,G,p.C1828G,Missense,-0.407530170453092,FUNC
1828,C,Y,p.C1828Y,Missense,-0.308549501299909,FUNC
1828,C,S,p.C1828S,Missense,-0.427149017058223,FUNC
1828,C,F,p.C1828F,Missense,-0.404389483894956,FUNC
1828,C,*,p.C1828*,Nonsense,-2.11895449749227,LOF
1828,C,C,p.C1828=,Synonymous,-0.258143618224925,FUNC
1828,C,W,p.C1828W,Missense,-0.0902053739383972,FUNC
1829,E,K,p.E1829K,Missense,-0.804182973764603,INT
1829,E,Q,p.E1829Q,Missense,-0.513444906280059,FUNC
1829,E,*,p.E1829*,Nonsense,-2.37575585502179,LOF
1829,E,A,p.E1829A,Missense,0.0527186007173151,FUNC
1829,E,G,p.E1829G,Missense,-0.150965351602071,FUNC
1829,E,V,p.E1829V,Missense,0.22636129340503,FUNC
1829,E,E,p.E1829=,Synonymous,-0.285887279278256,FUNC
1829,E,D,p.E1829D,Missense,-3.61778280157322e-06,FUNC
1829,E,D,p.E1829D,Missense,-0.197892936508826,FUNC
1830,A,T,p.A1830T,Missense,0.168084556825566,FUNC
1830,A,P,p.A1830P,Missense,-0.653638816115283,FUNC
1830,A,S,p.A1830S,Missense,-0.34428521949986,FUNC
1830,A,E,p.A1830E,Missense,-1.12572817242339,INT
1830,A,G,p.A1830G,Missense,-0.990940648228031,INT
1830,A,V,p.A1830V,Missense,-0.21197628861101,FUNC
1830,A,A,p.A1830=,Synonymous,0.372523097747277,FUNC
1830,A,A,p.A1830=,Synonymous,0.222020669045138,FUNC
1830,A,A,p.A1830=,Synonymous,0.32207869742392,FUNC
1831,P,T,p.P1831T,Missense,-0.0149928976380875,FUNC
1831,P,A,p.P1831A,Missense,0.0846757590074041,FUNC
1831,P,S,p.P1831S,Missense,-0.208516948121544,FUNC
1831,P,H,p.P1831H,Missense,-0.288263507102024,FUNC
1831,P,R,p.P1831R,Missense,-0.333529134984516,FUNC
1831,P,L,p.P1831L,Missense,0.0859567730190993,FUNC
1831,P,P,p.P1831=,Synonymous,0.0652499181228897,FUNC
1831,P,P,p.P1831=,Synonymous,-0.0382196455862462,FUNC
1831,P,P,p.P1831=,Synonymous,0.216073356969021,FUNC
1832,V,L,p.V1832L,Missense,-0.73647051721047,FUNC
1832,V,A,p.V1832A,Missense,-0.909867174020695,INT
1832,V,G,p.V1832G,Missense,-2.87157054358408,LOF
1833,V,M,p.V1833M,Missense,-2.18348435841623,LOF
1833,V,L,p.V1833L,Missense,-0.784809334832268,INT
1833,V,E,p.V1833E,Missense,-2.60593376622883,LOF
1833,V,A,p.V1833A,Missense,-0.661423186820916,FUNC
1833,V,V,p.V1833=,Synonymous,0.0211520405810629,FUNC
1833,V,V,p.V1833=,Synonymous,0.276208018235517,FUNC
1833,V,V,p.V1833=,Synonymous,-0.202315737700004,FUNC
1834,T,P,p.T1834P,Missense,0.131130517135967,FUNC
1834,T,A,p.T1834A,Missense,0.220196066243251,FUNC
1834,T,S,p.T1834S,Missense,-0.184100893811956,FUNC
1834,T,N,p.T1834N,Missense,-0.0496950637413476,FUNC
1834,T,S,p.T1834S,Missense,0.00440062810285297,FUNC
1834,T,I,p.T1834I,Missense,0.195638343757433,FUNC
1834,T,T,p.T1834=,Synonymous,-0.404060627646355,FUNC
1834,T,T,p.T1834=,Synonymous,0.219315149189388,FUNC
1834,T,T,p.T1834=,Synonymous,-0.187550858716403,FUNC
1835,R,R,p.R1835=,Synonymous,0.146524308634037,FUNC
1835,R,G,p.R1835G,Missense,-1.44783650749391,LOF
1835,R,*,p.R1835*,Nonsense,-2.29625062856965,LOF
1835,R,Q,p.R1835Q,Missense,-0.906347441715577,INT
1835,R,P,p.R1835P,Missense,-1.31208575342448,INT
1835,R,L,p.R1835L,Missense,-1.18927662322317,INT
1835,R,R,p.R1835=,Synonymous,0.094405192172702,FUNC
1835,R,R,p.R1835=,Synonymous,0.266734293961785,FUNC
1835,R,R,p.R1835=,Synonymous,-0.0582782589471287,FUNC
1836,E,K,p.E1836K,Missense,-0.299933275816698,FUNC
1836,E,Q,p.E1836Q,Missense,-0.00513366360205135,FUNC
1836,E,*,p.E1836*,Nonsense,-1.98224713430293,LOF
1836,E,A,p.E1836A,Missense,0.459904567193884,FUNC
1836,E,G,p.E1836G,Missense,-0.171450551543953,FUNC
1836,E,V,p.E1836V,Missense,-1.69001450474943,LOF
1836,E,E,p.E1836=,Synonymous,0.0676405451970248,FUNC
1836,E,D,p.E1836D,Missense,0.0719807612877564,FUNC
1836,E,D,p.E1836D,Missense,0.0193179634461506,FUNC
1837,W,R,p.W1837R,Missense,-2.46078117106402,LOF
1837,W,R,p.W1837R,Missense,-2.31441872512525,LOF
1837,W,G,p.W1837G,Missense,-2.56281847373706,LOF
1837,W,*,p.W1837*,Nonsense,-1.61165131759898,LOF
1837,W,S,p.W1837S,Missense,-2.22452869431682,LOF
1837,W,L,p.W1837L,Missense,-2.16887230883915,LOF
1837,W,*,p.W1837*,Nonsense,-2.37351547687928,LOF
1837,W,C,p.W1837C,Missense,-2.67815028387303,LOF
1837,W,C,p.W1837C,Missense,-1.69661300342761,LOF
1838,V,M,p.V1838M,Missense,-0.553037930952023,FUNC
1838,V,L,p.V1838L,Missense,-0.141088160699944,FUNC
1838,V,L,p.V1838L,Missense,0.00984233663659821,FUNC
1838,V,E,p.V1838E,Missense,-1.72587323841784,LOF
1838,V,A,p.V1838A,Missense,-0.213826976210602,FUNC
1838,V,G,p.V1838G,Missense,-1.97991531767534,LOF
1838,V,V,p.V1838=,Synonymous,0.272752752657283,FUNC
1838,V,V,p.V1838=,Synonymous,-0.26378808892828,FUNC
1838,V,V,p.V1838=,Synonymous,-0.0546409806881962,FUNC
1839,L,L,p.L1839=,Synonymous,-0.0133451257541699,FUNC
1839,L,V,p.L1839V,Missense,-1.91087818704072,LOF
1839,L,*,p.L1839*,Nonsense,-2.96032918974415,LOF
1839,L,S,p.L1839S,Missense,-2.49144382862178,LOF
1839,L,F,p.L1839F,Missense,-0.234922905900073,FUNC
1839,L,F,p.L1839F,Missense,0.106059676736309,FUNC
1840,D,N,p.D1840N,Missense,0.116605009970786,FUNC
1840,D,H,p.D1840H,Missense,-0.46591376590209,FUNC
1840,D,A,p.D1840A,Missense,0.0408873762011184,FUNC
1840,D,G,p.D1840G,Missense,-1.36424713854963,LOF
1840,D,V,p.D1840V,Missense,-1.79378434938463,LOF
1840,D,E,p.D1840E,Missense,-1.05547664109217,INT
1840,D,E,p.D1840E,Missense,-1.36946449858641,LOF
1840,D,D,p.D1840=,Synonymous,-0.625140475941253,FUNC
1841,S,R,p.S1841R,Missense,-1.72209824493603,LOF
1841,S,G,p.S1841G,Missense,-0.833876805808153,INT
1841,S,C,p.S1841C,Missense,-0.023697712368313,FUNC
1841,S,N,p.S1841N,Missense,-2.26214444108425,LOF
1841,S,T,p.S1841T,Missense,-1.86342946322187,LOF
1841,S,I,p.S1841I,Missense,-2.18578925794761,LOF
1841,S,R,p.S1841R,Missense,-1.46077385119623,LOF
1841,S,S,p.S1841=,Synonymous,0.380065819331908,FUNC
1841,S,R,p.S1841R,Missense,-2.92956795086696,LOF
1842,V,I,p.V1842I,Missense,-0.0181064202798805,FUNC
1842,V,L,p.V1842L,Missense,-0.370697641119487,FUNC
1842,V,L,p.V1842L,Missense,-0.680209350711637,FUNC
1842,V,E,p.V1842E,Missense,-2.02689288290543,LOF
1842,V,A,p.V1842A,Missense,-1.49481133957704,LOF
1842,V,G,p.V1842G,Missense,-1.92243402771164,LOF
1842,V,V,p.V1842=,Synonymous,0.280158504771365,FUNC
1842,V,V,p.V1842=,Synonymous,0.0669709007279156,FUNC
1842,V,V,p.V1842=,Synonymous,-0.109632717320251,FUNC
1843,A,T,p.A1843T,Missense,-0.0623836375813879,FUNC
1843,A,P,p.A1843P,Missense,-2.68452728381937,LOF
1843,A,S,p.A1843S,Missense,0.0603527965291615,FUNC
1843,A,E,p.A1843E,Missense,-2.81992075805621,LOF
1843,A,G,p.A1843G,Missense,-0.356104921713679,FUNC
1843,A,V,p.A1843V,Missense,-0.377550923552376,FUNC
1843,A,A,p.A1843=,Synonymous,0.200973167020785,FUNC
1843,A,A,p.A1843=,Synonymous,0.439539251835426,FUNC
1843,A,A,p.A1843=,Synonymous,0.263373096081001,FUNC
1844,L,I,p.L1844I,Missense,-0.268220294647479,FUNC
1844,L,V,p.L1844V,Missense,0.196108694684712,FUNC
1844,L,F,p.L1844F,Missense,-0.170767947483597,FUNC
1844,L,H,p.L1844H,Missense,-0.312582722261644,FUNC
1844,L,P,p.L1844P,Missense,-0.232681566234374,FUNC
1844,L,R,p.L1844R,Missense,-0.0615812686944012,FUNC
1844,L,L,p.L1844=,Synonymous,0.119725431646474,FUNC
1844,L,L,p.L1844=,Synonymous,-0.462075941038663,FUNC
1844,L,L,p.L1844=,Synonymous,-0.0755642438834202,FUNC
1845,Y,N,p.Y1845N,Missense,-0.0292407710214643,FUNC
1845,Y,H,p.Y1845H,Missense,0.121790821529931,FUNC
1845,Y,D,p.Y1845D,Missense,-0.811639346202481,INT
1845,Y,S,p.Y1845S,Missense,-0.224533049906489,FUNC
1845,Y,C,p.Y1845C,Missense,0.0417287263347877,FUNC
1845,Y,F,p.Y1845F,Missense,0.115162948712047,FUNC
1845,Y,*,p.Y1845*,Nonsense,-2.45245088436987,LOF
1845,Y,*,p.Y1845*,Nonsense,-2.53143635875928,LOF
1845,Y,Y,p.Y1845=,Synonymous,-0.129467374286386,FUNC
1846,Q,K,p.Q1846K,Missense,-0.0851731720580314,FUNC
1846,Q,E,p.Q1846E,Missense,-0.193852332471101,FUNC
1846,Q,*,p.Q1846*,Nonsense,-2.23335377469493,LOF
1846,Q,P,p.Q1846P,Missense,-1.96608910711693,LOF
1846,Q,R,p.Q1846R,Missense,0.280153918644277,FUNC
1846,Q,L,p.Q1846L,Missense,0.0984581445367511,FUNC
1846,Q,Q,p.Q1846=,Synonymous,0.0645680667756681,FUNC
1846,Q,H,p.Q1846H,Missense,-0.273650343656531,FUNC
1846,Q,H,p.Q1846H,Missense,-0.228948399107814,FUNC
1847,C,S,p.C1847S,Missense,-0.100741125364358,FUNC
1847,C,R,p.C1847R,Missense,0.255108725068747,FUNC
1847,C,G,p.C1847G,Missense,-0.0518672147865251,FUNC
1847,C,Y,p.C1847Y,Missense,0.137716861449271,FUNC
1847,C,S,p.C1847S,Missense,-0.0875868435855337,FUNC
1847,C,F,p.C1847F,Missense,-0.497292266098683,FUNC
1847,C,*,p.C1847*,Nonsense,-1.88097436313236,LOF
1847,C,W,p.C1847W,Missense,-0.127904430808619,FUNC
1847,C,C,p.C1847=,Synonymous,-0.116100913284565,FUNC
1848,Q,K,p.Q1848K,Missense,0.0658253023790965,FUNC
1848,Q,E,p.Q1848E,Missense,-0.353073612422102,FUNC
1848,Q,*,p.Q1848*,Nonsense,-2.07308652673108,LOF
1848,Q,P,p.Q1848P,Missense,-1.74979878757858,LOF
1848,Q,R,p.Q1848R,Missense,0.251439368051422,FUNC
1848,Q,L,p.Q1848L,Missense,-0.101285457945465,FUNC
1848,Q,Q,p.Q1848=,Synonymous,-0.463788965932701,FUNC
1848,Q,H,p.Q1848H,Missense,-0.607000666847142,FUNC
1848,Q,H,p.Q1848H,Missense,-1.18084330926485,INT
1849,E,K,p.E1849K,Missense,-0.142875393473933,FUNC
1849,E,Q,p.E1849Q,Missense,0.0470251233972239,FUNC
1849,E,*,p.E1849*,Nonsense,-1.89461419467771,LOF
1849,E,A,p.E1849A,Missense,-1.18497765007033,INT
1849,E,G,p.E1849G,Missense,-0.444983273687139,FUNC
1849,E,V,p.E1849V,Missense,-1.00953944603934,INT
1849,E,E,p.E1849=,Synonymous,-0.0310243507498182,FUNC
1849,E,D,p.E1849D,Missense,0.151566408891346,FUNC
1849,E,D,p.E1849D,Missense,-0.0840898724121253,FUNC
1850,L,M,p.L1850M,Missense,0.168902849034045,FUNC
1850,L,V,p.L1850V,Missense,-0.406771498247903,FUNC
1850,L,L,p.L1850=,Synonymous,0.566508646859577,FUNC
1850,L,Q,p.L1850Q,Missense,-0.635649812829347,FUNC
1850,L,P,p.L1850P,Missense,0.106617167469741,FUNC
1850,L,R,p.L1850R,Missense,-0.185898415178713,FUNC
1850,L,L,p.L1850=,Synonymous,-0.843029098067958,INT
1850,L,L,p.L1850=,Synonymous,0.136910668395231,FUNC
1850,L,L,p.L1850=,Synonymous,-0.256372252323303,FUNC
1851,D,N,p.D1851N,Missense,-0.253026438355311,FUNC
1851,D,H,p.D1851H,Missense,-0.0442973791968309,FUNC
1851,D,Y,p.D1851Y,Missense,-0.636700804247161,FUNC
1851,D,A,p.D1851A,Missense,-0.243173680692747,FUNC
1851,D,G,p.D1851G,Missense,-0.328077813881382,FUNC
1851,D,V,p.D1851V,Missense,-0.675031571224461,FUNC
1851,D,E,p.D1851E,Missense,-0.2369283501813,FUNC
1851,D,E,p.D1851E,Missense,0.00796172018660921,FUNC
1851,D,D,p.D1851=,Synonymous,-0.825888553758753,INT
1852,T,P,p.T1852P,Missense,-0.0674117123760091,FUNC
1852,T,A,p.T1852A,Missense,0.309628122141978,FUNC
1852,T,S,p.T1852S,Missense,-0.235598184550869,FUNC
1852,T,N,p.T1852N,Missense,-0.0744999668963853,FUNC
1852,T,S,p.T1852S,Missense,-0.131134371063331,FUNC
1852,T,I,p.T1852I,Missense,-0.152107501124813,FUNC
1852,T,T,p.T1852=,Synonymous,-0.183735036429715,FUNC
1852,T,T,p.T1852=,Synonymous,-0.225886266553234,FUNC
1852,T,T,p.T1852=,Synonymous,-0.431262926997201,FUNC
1853,Y,N,p.Y1853N,Missense,-2.16719537042397,LOF
1853,Y,H,p.Y1853H,Missense,-1.6528829107851,LOF
1853,Y,D,p.Y1853D,Missense,-3.35137155404902,LOF
1853,Y,S,p.Y1853S,Missense,-1.6982368729434,LOF
1853,Y,C,p.Y1853C,Missense,-2.76343815225029,LOF
1853,Y,F,p.Y1853F,Missense,-0.627988107807151,FUNC
1853,Y,*,p.Y1853*,Nonsense,-1.48991533504616,LOF
1853,Y,*,p.Y1853*,Nonsense,-2.15111921617674,LOF
1853,Y,Y,p.Y1853=,Synonymous,0.0414662990190648,FUNC
1854,L,M,p.L1854M,Missense,-0.0405343404771291,FUNC
1854,L,V,p.L1854V,Missense,0.158476440093227,FUNC
1854,L,L,p.L1854=,Synonymous,-0.308160232101454,FUNC
1854,L,Q,p.L1854Q,Missense,0.259387036126831,FUNC
1854,L,P,p.L1854P,Missense,-1.34387151005513,LOF
1854,L,R,p.L1854R,Missense,0.31245168508289,FUNC
1854,L,L,p.L1854=,Synonymous,-0.71215947251101,FUNC
1854,L,L,p.L1854=,Synonymous,-0.279599299148717,FUNC
1854,L,L,p.L1854=,Synonymous,-0.19148487382304,FUNC
1855,I,L,p.I1855L,Missense,0.233297291159429,FUNC
1855,I,V,p.I1855V,Missense,0.0462776303387803,FUNC
1855,I,L,p.I1855L,Missense,-0.218033758685176,FUNC
1855,I,K,p.I1855K,Missense,-0.863843894941789,INT
1855,I,T,p.I1855T,Missense,-0.291518974161822,FUNC
1855,I,R,p.I1855R,Missense,-0.464328415526521,FUNC
1855,I,I,p.I1855=,Synonymous,0.231182686157453,FUNC
1855,I,M,p.I1855M,Missense,0.0219408619017757,FUNC
1855,I,I,p.I1855=,Synonymous,-0.0153221623501722,FUNC